Podcasts · Health & Fitness

Core IM | Internal Medicine Podcast

Core IM Team

229 episodes

Core Internal Medicine via following series: 5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do? Gray Matters || Management Reasoning Hoofbeats || Dissecting clinical reasoning At the Bedside || Explore everyday challenges

Episodes page 1 of 5

  1. #221 Colon Cancer Screening After Age 75 | 5 Pearls Segment Part 3

    · 17 min

    “Should you stop screening for colorectal cancer (CRC) at 75?” This episode explores how to individualize screening decisions based on life expectancy, prior colonoscopy findings, and procedural risks. Learn how to…

  2. #220 Colon Cancer Screening Nuances: 5 Pearls Segment Part 2

    · 21 min

    “What’s the best way to screen?” This episode breaks down the pros, limitations, and follow-up needs of FIT, Cologuard, CT colonography, and colonoscopy to help you choose the right CRC screening option for your…

  3. #219 Updates in Triglycerides

    · 34 min

    “The triglycerides are high. Now what?” This episode breaks down a practical approach to elevated TGs, from knowing when to check ApoB or non-HDL-C to choosing lifestyle changes, lipid-lowering medications, and when to…

  4. #218 Early-Onset Colon Cancer: 5 Pearls Segment Part 1

    · 15 min

    “Too young for colon cancer.” This episode unpacks the red flags of early-onset colorectal cancer (CRC), from blood in the stool and iron deficiency anemia to persistent abdominal pain and changes in bowel habits, and…

  5. #217 Treatment for Alcohol Use Disorder: 5 Pearls Segment

    · 38 min

    “It didn’t work.” This episode breaks down practical treatment options (dosing options for naltrexone, acamprosate, topiramate, gabapentin) and counseling pearls to help you meet patients where they are and support…

  6. #216 Clinician Grief: At the Beside Segment

    · 40 min

    Have you ever lost a patient and found yourself thinking about them long after the shift ended? This episode explores the grief clinicians can carry after a patient dies, including the losses that aren’t always…

  7. #215 Gallbladder & Biliary Testing: 5 Pearls Segment

    · 35 min

    How to choose between RUQ ultrasound, CT, HIDA, MRCP, EUS, and ERCP based on the clinical picture? When should you move from diagnostic imaging to therapeutic ERCP, and what should you know about sphincterotomy,…

  8. #214 Hyponatremia Management: A Core IM Classic

    · 45 min

    Throwback: Should you really fluid-restrict every patient with SIADH? When can IV fluids make hyponatremia better or worse? Are salt tabs actually doing enough? And what can urine studies tell you before you start…

  9. #213 Hypertension First-Line Medications Troubleshooting | Bread & Butter Series

    · 33 min

    Why can lower-dose combinations be more effective and better tolerated than maximizing one medication? How to troubleshoot common challenges such as amlodipine edema, gout, electrolyte abnormalities, and the patient…

  10. #212 Top 10 Highlights of the New Lipid Guidelines

    · 24 min

    Learn from primary care docs what has been practiced and changed from the 2026 ACC/AHA Lipid Guidelines! Learn how the new CPR framework (Calculate, Personalize, Reclassify) and PREVENT risk calculator change statin…

  11. #211 Breaking Down MASLD vs. MASH and the MAESTRO-NASH & ESSENCE Trials: Beyond Journal Club Segment

    · 34 min

    MASLD affects nearly one in three adults worldwide, yet many patients remain undiagnosed until advanced fibrosis or cirrhosis develops. So, which patients should clinicians actually be screening? When is a FIB-4…

  12. #210 HTN in Dialysis: 5 Pearls Segment

    · 26 min

    What blood pressure should we target in patients on hemodialysis? Why volume control remains the foundation of treatment? How blood pressure targets differ from the general population. Learn practical pearls on…

  13. #209 Dialysis and Fluid Management: 5 Pearls Segment

    · 32 min

    Why is fluid management the most important part of dialysis care? This episode explores the fundamentals of hemodialysis, why ESKD patients have unique physiology, and how volume overload, not just hypertension, drives…

  14. #208 AI vs. Human with Post-Op AFib: Bread & Butter Series

    · 29 min

    Can AI manage post-op atrial fibrillation or does medicine still require human judgment? Using post-op AFib as a case study, we explore where algorithms help, where evidence falls short, and why clinical context still…

  15. #207 Is There a Doctor on Board? In-Flight Emergencies

    · 28 min

    We start with a gripping story of seizures and use it as a jumping-off point to unpack practical pearls for in-flight emergencies. Along the way: what’s actually in the emergency medical kit, when planes divert, how…

  16. #206 Eosinophilia: 5 Pearls Segment

    · 43 min

    Can you distinguish benign eosinophilia from a sign of serious disease, and know exactly when to act at the bedside? In this high-yield episode, test your clinical reasoning as we tackle: • When eosinophilia becomes…

  17. #205 Nutrition Studies, Coffee and the CRAVE Trial: Beyond Journal Club with the NEJM Group

    · 32 min

    Is coffee helping or harming our patients’ hearts? In this Beyond Journal Club, we unpack the CRAVE trial and use it as a lens to answer a bigger question: How should clinicians interpret nutrition research,…

  18. #204 Diabetic Foot Infections & Osteomyelitis: 5 Pearls Segment

    · 34 min

    Why can these infections be tricky? How to diagnose osteomyelitis at the bedside? Do we always need IV vs oral antibiotics? And the best for last: Simple, practical wound care strategies for medical students,…

  19. #203 POCUS for AKI & Dialysis | Real Cases That Changed Management

    · 29 min

    A dialysis patient with a chronic cough: is it COPD, or are they still volume overloaded? A patient with AKI and hyperkalemia says they’re still peeing — does that rule out post-obstructive AKI? A patient arrives in…

  20. #202 Dementia Part 2: Gray Matters Segment

    · 47 min

    Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help. In this episode we break down donepezil, memantine, and the new anti-amyloid drugs, and when to stop…

  21. #201: Dementia Part 1: Gray Matters Segment

    · 46 min

    Cognitive decline is tough for all parties. What are the high-yield questions to ask? What should you add to your one-liner? When do you stop using MOCA and try to clearly describe their functional status? Do all…

  22. #200: Insulin and QWINT-1 Trial in T2DM: Beyond Journal Club Segment with NEJM Group

    · 28 min

    From metformin to basal insulin to overlooked older medications, this episode reviews the T2D medication toolkit clinicians use every day. We then dive into new evidence on once-weekly insulin to help you individualize…

  23. #199 Privacy & Confidentiality: At the Bedside Segment

    · 38 min

    Is patient confidentiality absolute or conditional? When does protecting privacy put others at risk? Can you follow a former patient in the EHR for learning? Should you post a compelling case online even if it’s…

  24. #198 Microskills for Change That are Big Enough to Matter, Small Enough to Win

    · 29 min

    Baby alligators - those betrayals of purpose , or, death by a thousand paper cuts ! Check out our latest episode, where Dr. Eileen Barrett walks us through how to tackle baby alligators with: Regulated curiosity…

  25. #197 Hypercoagulability Part 2: 5 Pearls Segment

    · 38 min

    Gray zones of VTE management! How to approach anticoagulation duration in unprovoked, provoked-irreversible, and provoked-reversible clots? When dose-reduced DOACs make sense for long-term secondary prevention? What…

  26. #196 Stories of Courage and Career Development with Horn Award

    · 19 min

    We hope these stories resonate with anyone who has felt pulled between professional purpose and personal life, and remind you that you’re not alone in wanting both. 🔹 Sponsor: Oakstone CME Use the code "CORE30" for…

  27. #195 Antibiotic Duration & BALANCE Trial: Beyond Journal Club with NEJM Group

    · 22 min

    Antibiotic duration for bacteremia is something most of us learned by habit, not by trial data. In this episode, we walk through the BALANCE trial and use it as a lens to revisit how 1) host, 2) organism, and 3) source…

  28. #194: Severe Hypertriglyceridemia: 5 Pearls Segment

    · 38 min

    How quickly can triglycerides rise? At what threshold are patients at risk of pancreatitis or cardiovascular adverse outcomes? What do you have to rule out? How do you counsel on lifestyle changes? Which medications do…

  29. #193 Venous Congestion & VEXUS Interview with Dr. Ross Prager

    · 35 min

    Why is venous congestion not the same as volume overload? How can looking at IVC as well as doppler on the hepatic vein, portal vein, and/or intrarenal vein help? Can venous congestion explain someone's delirium? Or be…

  30. #192 Debate on First-Line Medications for Diabetes

    · 37 min

    SGLT-2i vs. GLP-1? vs Metformin? How do you balance the cost and coverage of first-line options like metformin, SGLT-2, and GLP-1s? How do you choose between SGLT-2 and GLP-1s for comorbidities like CAD or CKD? And how…

  31. #191 Hepatorenal Syndrome Part 2 on Management: 5 Pearls Segment

    · 31 min

    What really works when treating HRS? Vasoconstrictors like terlipressin vs. norepinephrine vs. midodrine: how do we decide which to use? Do you give albumin? When do you give Lasix or another diuretic? When is the…

  32. #190: Hepatorenal Syndrome Part 1: 5 Pearls Segment

    · 36 min

    HRS-AKI vs. other causes of AKI in cirrhosis: What do serum or urine sodium clues, albumin challenges, and shifting diagnostic criteria actually reveal about getting the diagnosis right? 🔹 Sponsor: Oakstone CME Use…

  33. #189 Bisphosphonates and Fracture Prevention Trial: Beyond Journal Club with NEJM Group

    · 31 min

    Who’s really at risk for fractures, and how should we be treating them? Most fragility fractures occur in patients without osteoporosis. Should we rethink who gets treated? And could just one or two IV infusions…

  34. #188 Orthostatic Hypotension Part 2: Gray Matters Segment

    · 36 min

    Medications for orthostatic hypotension! When to initiate treatment, how to use them safely, and what to do when new issues arise during treatment. How do those change if someone has autonomic failure? What do you do…

  35. #187 Orthostatic Hypotension Part 1: Gray Matters Segment

    · 37 min

    Learn specific, practical ways to counsel patients on non-pharmacologic interventions. What is our goal with OH treatment? Is it the blood pressure number that matters? How do we avoid missing neurogenic causes of…

  36. #186 Pneumothorax: 5 Pearls Segment

    · 37 min

    Next time you’re squinting at a chest tube, feel confident you know exactly what to look for and why. Hear it explained in a way that really sticks! 🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio Companion Use the code…

  37. #185 Neutropenia: 5 Pearls Segment

    · 42 min

    How do you work up neutropenia? When is neutropenia benign? When do neutrophils recover? How can you diagnose neutropenic fever in the first 15 minutes and start antibiotics in the first 60 minutes? Do you always add…

  38. #184 Stories for the Feels

    · 11 min

    Have a good laugh and reflect deeply with these three stories that hit the feels in different ways. If you'd love to hear more stories from Dr. Maria Rosasco, check out some of her other appearances on the podcast:…

  39. #183 Diagnose the Clinician: Hoofbeats Segment

    · 33 min

    What went wrong? What were the reasoning or contextual missteps that led us astray? 🔹 Sponsor: NEJM Fellowship Program, click here to learn more and/or apply! Due Aug 1, 2025 🔹 Transcript and Show Notes Timestamps:…

  40. #182 Pleural Effusions: 5 Pearls Segment

    · 36 min

    • Imaging Pearls | (01:12) • Deciding on Thoracentesis | (04:00) • Light’s Criteria and Pseudoexudates | (07:00) • Pleural Fluid Studies: pH and Cell Differential | (16:56) • Diagnosing and Treating Parapneumonic…

  41. #181 July Stories 3.0

    · 16 min

    Listen for some good laughs and relatable stories! In this episode, we share raw and real stories from July — from rapid responses to unexpected kindness — and reflect on the emotional weight of starting out in…

  42. #180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group

    · 27 min

    How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care, examine how evidence evolved, and explore the…

  43. #179 Invasive Fungal Disease: 5 Pearls Segment

    · 45 min

    🔹 What is invasive fungal disease, and who is most at risk for developing invasive fungal disease? (~ 02:46) 🔹 What are the main classes of fungi? (~11:35) 🔹 What are the pros and cons of B-D Glucan and Galactomannan…

  44. #178 Continuous Glucose Monitor (CGM): 5 Pearls Segment

    · 34 min

    🔹What are clinically relevant limitations of an A1c vs. a CGM (1:40) 🔹What do the different parts of the ambulatory glucose profile tell you? (09:59) 🔹What are common pitfalls, medications, lifestyle patterns that…

  45. #177 Interventional Radiology (IR) 101: 5 Pearls Segment

    · 44 min

    🔹When is an U/S vs. CT vs. MRI helpful before consulting Interventional Radiology? 🔹What factors go into an IR pre-op evaluation? 🔹 When do drains go in, and when do they come out? 🔹 When a patient has trouble with…

  46. #176 Constipation Medications: 5 Pearls Segment

    · 40 min

    🔹 High-yield reversible causes of constipation? (02:26) 🔹 Which type of fiber is more helpful? And is more hydration really better? And bulk-forming laxatives (9:03) 🔹 Osmotic vs Stimulant Laxatives (15:06) 🔹…

  47. #175 A Revolution in HIV Prevention & The PURPOSE Trials: Beyond Journal Club Segment with NEJM Group

    · 28 min

    How good are we at preventing HIV? How do efficacy and effectiveness differ? We journey from oral pre-exposure prophylaxis (PrEP) to long-acting injectables, and then to the PURPOSE trials, which look at the use of…

  48. #174 Lp(a) and ASCVD Risk: 5 Pearls Segment

    · 43 min

    What does Lipoprotein(a) tell us that a standard lipid panel doesn’t? Should we be testing everyone for it? Dive into the genetics, clinical implications, and evolving management strategies for Lp(a). Learn how to…

  49. #173 Hypercoagulability Workup: 5 Pearls Segment

    · 45 min

    A new way to think of clots beyond provoked vs. unprovoked: Learn all about how important it is to think about reversibility! What patient states affect the inherited thrombophilia testing? Learn the nuances and…

  50. #172 Microplastics and Macro CV Health Problems: Beyond Journal Club on APACHe Study with NEJM Group

    · 34 min

    What is the impact of microplastics on human health? How can we use observational data to support the argument that microplastics may lead to poor health outcomes? Join us as we tackle these questions and discuss the…

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