Podcasts · Core IM | Internal Medicine Podcast
#213 Hypertension First-Line Medications Troubleshooting | Bread & Butter Series
· 33 min
Episode #213 Hypertension First-Line Medications Troubleshooting | Bread & Butter Series
Why can lower-dose combinations be more effective and better tolerated than maximizing one medication? How to troubleshoot common challenges such as amlodipine edema, gout, electrolyte abnormalities, and the patient who says they cannot tolerate anything? Why ACT (ARBs, Calcium Channel Blockers, Thiazides) is the preferred first-line framework, and how to personalize medication choices based on comorbidities and side effects.
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🔹Transcript and Shownotes
03:00 | Diagnosing Hypertension
04:10 | When to Start Combination Therapy Instead of Monotherapy
07:00 | Choosing First-Line Therapy Using the ACT Framework
13:23 | Why ARBs Are Often Preferred Over ACE Inhibitors
16:02 | Choosing the Right ARB: Candesartan vs Losartan
18:39 | Comparing Potency & Duration Across First-Line Antihypertensives
20:54 | Amlodipine Edema: Why It Happens and How to Fix It
23:54 | Thiazides: Practical Tips, Electrolyte Problems & Class-Killer Side Effects
29:33 | Managing Patients Who 'Can't Tolerate' Blood Pressure Medications
Tags: Hypertension Management, High Blood Pressure, Primary Care, Internal Medicine, Core IM
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Transcript
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