Harrison's PodClass: Internal Medicine Cases and Board Prep

Episodes page 1 of 5

1. Ep 218: An 83-Year-Old with Chronic Lymphocytic Leukemia

   22 Oct 2026 · 11 min · Episode 218

   This case reviews complications associated with chronic lymphocytic leukemia. Harrison's Principles of Internal Medicine, 22nd Edition

2. Ep 217: A 23-Year-Old Traveling

   15 Oct 2026 · 8:44 · Episode 217

   This episode reviews rabies epidemiology, prevention, clinical presentation, and treatment. Harrison's Principles of Internal Medicine, 22nd Edition

3. Ep 216: A 48-Year-Old with PRES

   8 Oct 2026 · 6:00 · Episode 216

   This episode reviews the treatment options for posterior reversible encephalopathy syndrome (PRES). Harrison's Principles of Internal Medicine, 22nd Edition

4. Ep 215: A 43-Year-Old with Pericarditis

   1 Oct 2026 · 5:11 · Episode 215

   This episode reviews the treatment of pericarditis. Harrison's Principles of Internal Medicine, 22nd Edition

5. Ep 214: A 63-Year-Old with Myasthenia Gravis

   24 Sep 2026 · 7:23 · Episode 214

   This episode reviews the treatment of myasthenia gravis. Harrison's Principles of Internal Medicine, 22nd Edition

6. Ep 213: A 48-Year-Old with Gradually Progressive Shortness of Breath

   17 Sep 2026 · 7:20 · Episode 213

   This episode discusses medications associated with the long-term development of pulmonary fibrosis. Harrison's Principles of Internal Medicine, 22nd Edition

7. Ep 212: A 45-Year-Old with Palpitations

   10 Sep 2026 · 7:45 · Episode 212

   This episode reviews the causes and evaluation of palpitations. Harrison's Principles of Internal Medicine, 22nd Edition

8. Ep 211: A 63-Year-Old Man Who Reports Difficulty Speaking and Swallowing

   4 Sep 2026 · 9:15

   This episode reviews the diagnostic workup of myasthenia gravis. Harrison's Principles of Internal Medicine, 22nd Edition

9. Ep 210: An 18-Year-Old with a Rash

   27 Aug 2026 · 8:48 · Episode 210

   This episode reviews the clinical presentation and complications of measles. Harrison's Principles of Internal Medicine, 22nd Edition

10. Ep 209: A 65-Year-Old with an Abnormal Chest CT

    20 Aug 2026 · 8:37 · Episode 209

    This episode reviews occupational lung exposures. Harrison's Principles of Internal Medicine, 22nd Edition

11. Ep 208: A 36-Year-Old with ECG Changes

    14 Aug 2026 · 7:00 · Episode 208

    This episode reviews ECG changes commonly seen with electrolyte abnormalities. Harrison's Principles of Internal Medicine, 22nd Edition

12. Ep 207: A 75-Year-Old with New-Onset Seizures

    6 Aug 2026 · 6:39 · Episode 207

    This episode reviews management of complications related to brain metastases. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

13. Ep 206: A 58-Year-Old with Weight Loss, Cough, and Blood-Streaked Sputum

    30 Jul 2026 · 8:45 · Episode 206

    This episode reviews the diagnosis and treatment of tuberculosis. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

14. Ep 205: A 33-Year-Old Starting Treatment for Psoriasis

    23 Jul 2026 · 8:38 · Episode 205

    This episode talks about tuberculosis screening and PPD interpretation. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

15. Ep 204: A 72-Year-Old with Worsening Exertional Dyspnea

    16 Jul 2026 · 12 min · Episode 204

    This episode discusses ischemic cardiomyopathy and goal-directed medical therapy. Harrison's Guide to Inpatient Medicine is now available on AccessMedicine and for preorder on Amazon. Read more on this topic in…

16. Ep 203: A 42-Year-Old with Cirrhosis

    9 Jul 2026 · 8:55 · Episode 203

    This episode reviews complications and management of cirrhosis. Harrison's Guide to Inpatient Medicine is now available on AccessMedicine and for preorder on Amazon. Read more on this topic in Harrison's. Harrison's…

17. Ep 202: A 68-Year-Old with Acute Abdominal Pain

    2 Jul 2026 · 13 min · Episode 202

    This episode reviews the diagnosis and management of common causes of acute abdominal pain. Harrison's Guide to Inpatient Medicine is now available on AccessMedicine and for preorder on Amazon. Read more on this topic…

18. Ep 201: A 67-Year-Old with Scleroderma

    26 Jun 2026 · 7:54 · Episode 201

    This episode discusses medical emergencies and complications in patients with scleroderma. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

19. Ep 200: A 67-Year-Old with Fatigue and Puffiness

    18 Jun 2026 · 8:20

    This episode reviews the pathophysiology and typical clinical and laboratory findings of scleroderma. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

20. Ep 199: A 75-Year-Old With Neuropathic-Type Pain and Weakness

    11 Jun 2026 · 8:38 · Episode 199

    This episode reviews causes and consequences of macrocytic anemia. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

21. Ep 198: A 54-Year-Old with Aortic Stenosis

    5 Jun 2026 · 8:53 · Episode 198

    This episode reviews the diagnosis and complications of aortic stenosis. Read more on this topic in Harrison's Harrison's Principles of Internal Medicine, 22nd Edition

22. Ep 197: A 77-Year-Old Hospitalized with Pneumonia

    28 May 2026 · 8:56 · Episode 197

    This episode reviews the diagnostic workup of patients with confusion while hospitalized for pneumonia. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

23. Ep 196: A 48-Year-Old with Worsening Headaches

    21 May 2026 · 7:22 · Episode 196

    This episode reviews the diagnostic workup for causes of headache. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

24. Ep 195: A 43-Year-Old with Chest Pain

    14 May 2026 · 8:01 · Episode 195

    This episode goes through the diagnostic maneuvers involved in diagnosing various causes of chest pain. Read more on this topic in Harrison's Harrison's Principles of Internal Medicine, 22nd Edition

25. Ep 194: A 57-Year-Old with Hypercalcemia

    7 May 2026 · 7:09 · Episode 194

    This episode reviews some of the signs and treatment of hypercalcemia. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

26. Ep 193: A 40-Year-Old with Fevers, Congestion, and Cough

    30 Apr 2026 · 10 min · Episode 193

    This episode reviews the clinical manifestations and differential diagnosis of vasculitis syndromes. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

27. Ep 192: A 44-Year-Old Concerned about MEN Syndromes

    23 Apr 2026 · 7:42 · Episode 192

    This episode reviews the clinical characteristics of multiple endocrine neoplasia (MEN) syndromes. Read more on this topic in Harrison's Harrison's Principles of Internal Medicine, 22nd Edition

28. Ep 191: A 38-Year-Old with Fever, Hypotension, and Confusion

    17 Apr 2026 · 8:56 · Episode 191

    This episode goes through laboratory findings of critically ill patients, their etiologies, and the corresponding syndromes. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd…

29. Ep 190: A 45-Year-Old with Flank Pain

    9 Apr 2026 · 11 min · Episode 190

    This episode reviews the diagnosis, pathophysiology, treatment, and management of patients with nephrolithiasis. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

30. Ep 189: A 52-Year-Old with Hypertension

    2 Apr 2026 · 9:31 · Episode 189

    This episode reviews secondary causes of hypertension and the work-up and evaluation to determine the cause. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

31. Ep 188: A 22-Year-Old with Abnormal Serum Bilirubin

    26 Mar 2026 · 9:03 · Episode 188

    This episode reviews common causes of hyperbilirubinemia and how to differentiate among its various causes. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

32. Ep 187: A 73-Year-Old with Complications from Renal Dysfunction

    19 Mar 2026 · 7:15 · Episode 187

    This episode reviews common complications of renal dysfunction. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

33. Ep 186: A 45-Year-Old with Elevated Calcium

    12 Mar 2026 · 9:07 · Episode 186

    This episode reviews the workup and diagnosis of hypercalcemia. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

34. Ep 185: An 89-Year-Old with Lack of Appetite and Weight Loss

    5 Mar 2026 · 5:27 · Episode 185

    This episode discusses key concepts in the care of the geriatric patient. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

35. Ep 184: A 65-Year-Old with Anemia

    26 Feb 2026 · 8:46 · Episode 184

    This episode reviews peripheral blood smears and how they guide diagnosis. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

36. Ep 183: A 75-Year-Old with Acute Fever and Altered Mental Status

    19 Feb 2026 · 11 min · Episode 183

    This episode discusses the symptoms and laboratory findings seen in patients with West Nile virus. Read more on this topic in Harrison's chapters: Encephalitis Arthropod-Borne and Rodent-Borne Virus Infections…

37. Ep 182: A 64-Year-Old with Abnormal Colonoscopy

    12 Feb 2026 · 8:48 · Episode 182

    This episode reviews the epidemiology and complications related to diverticular disease. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

38. Ep 181: A 64-Year-Old with Fatigue and Low-Grade Fevers

    5 Feb 2026 · 7:51 · Episode 181

    This episode discusses types of cardiac murmurs. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

39. Ep 180: A 64-Year-Old with Fever

    22 Jan 2026 · 11 min · Episode 180

    This episode discusses fever of unknown origin (FUO) and unexplained inflammation. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

40. Ep 179: A 62-Year-Old with Fatigue

    15 Jan 2026 · 8:53 · Episode 179

    This episode reviews common causes of fatigue, and the additional history and physical findings needed for the next steps in evaluation. Read more on this topic in Harrison's. Harrison's Principles of Internal…

41. Ep 178: A 57-Year-Old with Neck Pain

    8 Jan 2026 · 11 min · Episode 178

    This episode reviews the diagnostic approach to acute neck pain. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

42. Ep 177: A Patient with Low Blood Pressure

    18 Dec 2025 · 8:35 · Episode 177

    Part of our Physiology at the Bedside collection, this episode reviews the physiology of shock. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

43. Ep 176: A 34-Year-Old Who Skipped Medications

    11 Dec 2025 · 7:03 · Episode 176

    This is the next episode in our Physiology at the Bedside series and reviews complications that can arise when a patient forgets to take their medications. Read more on this topic in Harrison's. Harrison's Principles…

44. Ep 175: A 38-Year-Old with Cardiac Arrest

    4 Dec 2025 · 10 min · Episode 175

    Continuing our Physiology at the Bedside series, this episode examines the potential causes of pulseless electrical activity (PEA) arrest. Read more on this topic in Harrison's. Harrison's Principles of Internal…

45. Ep 174: A 65-Year-Old Man with Dyspnea on Exertion

    28 Nov 2025 · 8:23 · Episode 174

    From our Physiology at the Bedside series, this episode reviews pulmonary function tests. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

46. Ep 173: A 48-Year-Old Woman with Heart Failure

    20 Nov 2025 · 8:14 · Episode 173

    In this installment of our Physiology at the Bedside series, we cover heart failure and the physiology behind its different types. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine,…

47. Ep 172: A 52-Year-Old Man with an Increased Respiratory Rate

    13 Nov 2025 · 8:54 · Episode 172

    In this episode in our “Physiology at the Bedside” series, we discuss the causes and pathophysiology of acidosis. Read more on this topic in Harrison's Harrison's Principles of Internal Medicine, 22nd Edition

48. Ep 171: A 19-Year-Old Woman with Lower Extremity Edema

    6 Nov 2025 · 7:11 · Episode 171

    The first episode in the series, “Physiology at the Bedside” discussing the mechanisms of lower extremity edema. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

49. Ep 170: A 35-Year-Old with Changes in Vision

    30 Oct 2025 · 10 min · Episode 170

    This episode is a discussion with Harrison’s editor, Dr. Andrew Josephson, about multiple sclerosis. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition

50. Ep 169: A 65-Year-Old with Right-Sided Weakness

    23 Oct 2025 · 9:16 · Episode 169

    This episode is a discussion with Harrison’s editor, Dr. Andrew Josephson, about the treatment of stroke. Read more on this topic in Harrison's. Harrison's Principles of Internal Medicine, 22nd Edition