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A ball and stick model of β-D-fructofuranose structure (found in corn syrup) shown next to sweet corn, along with a ball and stick model of β-D-fructopyranose structure (found in honey) shown next to a honeybee and flower.

Course7.0515 lectures21 h 27 min

General Biochemistry

Prof. Michael Yaffe and Prof. Matthew Vander Heiden · Massachusetts Institute of Technology

Start with lecture 1 At MIT OpenCourseWare

About

This course focuses on contributions of biochemistry toward an understanding of the structure and functioning of organisms, tissues, and cells. Topics include:

Chemistry and functions of constituents of cells and tissues and the chemical and physical-chemical basis for the structures of nucleic acids, proteins, and carbohydrates.

Basic enzymology and biochemical reaction mechanisms involved in macromolecular synthesis and degradation, signaling, transport, and movement.

General metabolism of carbohydrates, fats, and nitrogen-containing materials such as amino acids, proteins, and related compounds.

NOTE: The first half of this course, taught by Prof. Yaffe, is available on the MITx platform as 7.05x Biochemistry: Biomolecules, Methods, and Mechanisms. This OCW website provides content primarily from the second half with Prof. Vander Heiden, which focuses on metabolism.

Lectures

Video Lectures

  1. Lecture 12: Carbohydrates/Introduction to Membranes 1 h 10 min · Video
  2. Lecture 19: Introduction to Metabolism/Polysaccharides/Bioenergetics/Intro Pathways 1 h 23 min · Video
  3. Lecture 20: Bioenergetics/Intro Pathways/Glycolysis I 1 h 25 min · Video
  4. Lecture 21: Glycolysis II/Regulation 1 h 25 min · Video
  5. Lecture 22: Glucogenesis/Carbohydrate Storage/TCA Cycle I 1 h 28 min · Video
  6. Lecture 23: TCA Cycle II 1 h 30 min · Video
  7. Lecture 24: Lipids and Fatty Acid Oxidation 1 h 22 min · Video
  8. Lecture 25: Oxidative Phosphorylation 1 h 31 min · Video
  9. Lecture 26: Oxidative Phosphorylation/Photosynthesis I 1 h 24 min · Video
  10. Lecture 27: Photosynthesis II/CO2 Assimilation 1 h 33 min · Video
  11. Lecture 28: Pentose Phosphate Pathway 1 h 30 min · Video
  12. Lecture 29: Lipid Synthesis 1 h 28 min · Video
  13. Lecture 30: Nitrogen/Amino Acid Metabolism I 1 h 31 min · Video
  14. Lecture 31: Amino Acid Metabolism II 1 h 29 min · Video
  15. Lecture 32: Nucleotide Metabolism 1 h 26 min · Video

Syllabus and materials

At MIT OpenCourseWare, as the course publishes them.

Credits and licence

Institution
Massachusetts Institute of Technology
Department
Biology
Taught by
Prof. Michael Yaffe, Prof. Matthew Vander Heiden
Term
Spring 2020
Level
Undergraduate
Language
English
Subjects
Chemistry, Biology
Source
MIT OpenCourseWare
Licence
CC BY-NC-SA 4.0, as MIT OpenCourseWare states it. Non-commercial use only. MIT OpenCourseWare's terms
Attribution
Prof. Michael Yaffe, Prof. Matthew Vander Heiden. General Biochemistry. Spring 2020. Massachusetts Institute of Technology: MIT OpenCourseWare, https://ocw.mit.edu/. License: Creative Commons BY-NC-SA.
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