Course10210609658 lectures
Introduction to Cell Biology
Prof. Nagaraj Balasubramanian and Prof. Girish Ratnaparkhi · IISER Pune
About
This course aims to introduce students to biomolecules and important fundamental concepts in cellular biochemistry, genetics and cellular organisation. It is aimed to give you an insight into how biomolecules work and help drive cellular architecture and function in a eukaryotic cell. In the first part, we focus on the information that makes the cell tick; from its storage in DNA to its conversion to executive molecules such as RNA and protein that perform essential routine processes in the cell. The central dogma is used as a guide to explore the structure of DNA, RNA and Protein and also explore the mechanisms of DNA replication, transcription and translation. Also touched upon are other important molecules such as water, carbohydrates and lipids. In the second part, we introduce basic mechanisms of heredity, as discovered by Gregor Mendel, in a modern context. In the third part, we will be discussing cell theory and the evolution of complexity in cells and the role compartmentalisation plays in mediating the same. The organisation of cells starting from the cell membrane as we move into the cell will be discussed. We will be looking at the role cytoskeleton have in cellular organisation and function. We will also be discussing organisation, role and regulation of cell organelles, everything from the endomembrane system to lysosomes to the nucleus. Eventually, we will be briefly discussing how all these cellular components come together to drive the process of cell division.
Intended audience: First year undergraduate Biology students
Prerequisites: Any student who is starting a BSc course in Biology would find this useful.
Lectures
Week 1
- An Overview of Central Dogma of Molecular Biology - Part 1
- An Overview of Central Dogma of Molecular Biology - Part 2
- Central Dogma : The DNA Structure - Part 1
- Central Dogma : The DNA Structure - Part 2
- Central Dogma : The DNA Structure - Part 3
- Central Dogma : Replication of DNA - Part 1
- Central Dogma : Replication of DNA - Part 2
Week 2
- Central Dogma: Transcription - Part 1
- Central Dogma: Transcription - Part 2
- Central Dogma: Transcription - Part 3
- Central Dogma: Tranlation- Part 1
- Central Dogma: Tranlation- Part 2
- Central Dogma: Tranlation- Part 3
- Protein Structure, Folding and Function - Part 1
- Protein Structure, Folding and Function - Part 2
- Secondary Strcuture of Proteins: Ramachandran Plot - Part 1
- Secondary Strcuture of Proteins: Ramachandran Plot - Part 2
- Protein Structure, Folding and Function - Part 3
- Protein Structure, Folding and Function - Part 4
- Protein Structure, Folding and Function - Part 5
Week 3
- Protein Structure, Folding and Function - Part 6
- Enzymes, Carbohydrates and Lipids
- Introduction to Genetics - Part 1
- Introduction to Genetics - Part 2
- Introduction to Genetics - Part 3
- Mendilian and Non-Mendilian Genetics - Part 1
- Mendilian and Non-Mendilian Genetics - Part 2
- Mendilian and Non-Mendilian Genetics - Part 3
Week 4
- Introduction to Microscopy - Part 1
- Introduction to Microscopy - Part 2
- Introduction to Microscopy - Part 3
- Biology of Cells - Part 1
- Biology of Cells - Part 2
- Complexity and Compartmentalization in Cells - Part 1
- Complexity and Compartmentalization in Cells - Part 2
- Endosymbiont Theory
Week 5
- Structure of the Cell: Cell Wall and Cell Membrane
- Structure of the Cell: Discussion Session
- Plasma Membrane: The Boundaries of Life
- Plasma Membrane: Discussion Session
- Introduction to Cytoskeleton - Part 1
- Cytoskeleton: Discussion Session 1
Week 6
- Introduction to Cytoskeleton - Part 2
- Cytoskeleton: Discussion Session 2
- Motor Proteins in Cell
- Motor Proteins in Cell: Discussion Session
- Discussion on Directionality of Motor Protein
Week 7
- Endomembrane System of Cells - Part 1
- Endomembrane System of Cells: Discussion Session 1
- Endomembrane System of Cells - Part 2
- Endomembrane System of Cells: Discussion Session 2
- Endomembrane System of Cells - Part 3
- Endomembrane System of Cells: Discussion Session 3
Week 8
Syllabus and materials
At NPTEL, as the course publishes them.
Credits and licence
- Institution
- IISER Pune
- Department
- Biotechnology
- Taught by
- Prof. Nagaraj Balasubramanian, Prof. Girish Ratnaparkhi
- Level
- Undergraduate
- Language
- English
- Subjects
- Biology
- Source
- NPTEL
- Licence
- CC BY-NC-SA, as NPTEL states it. Non-commercial use only. NPTEL's terms
- Attribution
- NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge. Coordinated by IIT Madras.
- Who can watch
- NPTEL gives no rating. Invisible Network shows it to Tweens profiles and older, judged from what the source says about it. How courses are placed
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