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Course10210555463 lectures

Introduction to complex biological systems

Prof. Soumya De Prof. Dibyendu Samanta · IIT Kharagpur

Start with lecture 1 At NPTEL

Lectures

week-01

  1. Lecture 1: Fundamentals of a Living System Video
  2. Lecture 2: Discovery of Genetic Material Video
  3. Lecture 3: Chemical and Physical Properties of Nucleic Acids Video
  4. Lecture 4: Introduction to DNA Replication Video
  5. Lecture 5: Mechanistic Overview of DNA Replication Video

week-02

  1. Lecture 6: Gene expression and The Central Dogma of Molecular Biology Video
  2. Lecture 7: Transcription: Involved Machineries and Processes Video
  3. Lecture 8: Translation: Decoding the message of an mRNA Video
  4. Lecture 9: Time-space correlation and fidelity of transcription and translation Video
  5. Lecture 10: Regulation of gene expression Video

week-03

  1. Lecture 11: Amino acids, hierarchy of protein structure Video
  2. Lecture 12: Protein folding, Folding funnel, Anfinsen’s experiment Video
  3. Lecture 13: Protein-ligand interactions Video
  4. Lecture 14: Allosteric regulation of proteins, e.g. haemoglobin Video
  5. Lecture 15: Membrane proteins Video

week-04

  1. Lecture 16: Introduction to enzymes Video
  2. Lecture 17: Theory of enzyme catalysis Video
  3. Lecture 18: Specificity of enzymes, e.g. Chymotrypsin Video
  4. Lecture 19: Enzyme inhibition. Types and mechanism of inhibitors. Design of inhibitors. Video
  5. Lecture 20: Engineered enzymes and their applications Video

week-05

  1. Lecture 21: Introduction to cells Video
  2. Lecture 22: Visualizing cells Video
  3. Lecture 23: Cell division cycle Video
  4. Lecture 24: Stem Cells Video
  5. Lecture 25: Cancer Video

week-06

  1. Lecture 26: Overview of the development of multicellular organization Video
  2. Lecture 27: Pattern formation and growth Video
  3. Lecture 28: Cell division, cell death and tissue homeostasis Video
  4. Lecture 29: Cell Junctions and extracellular matrix Video
  5. Lecture 30: Introduction to Neuron and the action potential Video

week-07

  1. Lecture 31: Vitamins and introduction to bioenergetics Video
  2. Lecture 32: Glycolysis, Gluconeogenesis and PPP Video
  3. Lecture 33: Citric Acid Cycle and Oxidative Phosphorylation Video
  4. Lecture 34: Photosynthesis Video
  5. Lecture 35: Photosynthetic carbohydrate synthesis Video

week-08

  1. Lecture 36: Evolution of life on earth Video
  2. Lecture 37: Protein evolution Video
  3. Lecture 38: Mechanisms of evolution Video
  4. Lecture 39: Evolution of eye Video
  5. Lecture 40: Model orgamisms Video

week-09

  1. Lecture 41: Introduction to microbial world and infectious diseases Video
  2. Lecture 42: Cell organization and unique features of bacteria Video
  3. Lecture 43: Understanding viruses - the smallest enemy Video
  4. Lecture 44: Pathogenicity and infection Video
  5. Lecture 45: Antibacterial and Antiviral Drugs Video

week-10

  1. Lecture 46: Introduction to the immune system Video
  2. Lecture 47: Innate immunity: the first lines of defense Video
  3. Lecture 48: Adaptive immune response Video
  4. Lecture 49: Antibody- structure, function and diversity Video
  5. Lecture 50: Vaccines and immunotherapy Video

week-11

  1. Lecture 51: Visualizing and analyzing nucleic acids: Gel electrophoresis and PCR Video
  2. Lecture 52: Visualizing and analyzing nucleic acids: DNA Sequencing Video
  3. Lecture 53: Overview of genetic engineering and its impact on society Video
  4. Lecture 54: Genetic engineering: Methods and applications Video
  5. Lecture 55: Cloning and Gene manipulation Video

week-12

  1. Lecture 56: Characterization methods Video
  2. Lecture 57: Chromatographic methods Video
  3. Lecture 58: protein - ligand interactions Video
  4. Lecture 59: Immunoassay techniques Video
  5. Lecture 60: Landmark experiments in biology Video

Live Session

  1. Live Session 18-02-2025 Video
  2. Live Session 19-03-2025 Video
  3. Live Session 16-04-2025 Video

Syllabus and materials

At NPTEL, as the course publishes them.

Credits and licence

Institution
IIT Kharagpur
Department
Biotechnology
Teacher
Prof. Soumya De Prof. Dibyendu Samanta
Level
Undergraduate
Language
English
Subjects
Biology
Source
NPTEL
Licence
CC BY-NC-SA, as NPTEL states it. Non-commercial use only. NPTEL's terms
Attribution
NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge.
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