Learn · Introduction to complex biological systems
Lecture 12 of 63week-03
Lecture 12: Protein folding, Folding funnel, Anfinsen’s experiment
Prof. Soumya De Prof. Dibyendu Samanta · IIT Kharagpur
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- Introduction to complex biological systems, IIT Kharagpur (at NPTEL)
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All the lectures
- Lecture 1: Fundamentals of a Living System
- Lecture 2: Discovery of Genetic Material
- Lecture 3: Chemical and Physical Properties of Nucleic Acids
- Lecture 4: Introduction to DNA Replication
- Lecture 5: Mechanistic Overview of DNA Replication
- Lecture 6: Gene expression and The Central Dogma of Molecular Biology
- Lecture 7: Transcription: Involved Machineries and Processes
- Lecture 8: Translation: Decoding the message of an mRNA
- Lecture 9: Time-space correlation and fidelity of transcription and translation
- Lecture 10: Regulation of gene expression
- Lecture 11: Amino acids, hierarchy of protein structure
- Lecture 12: Protein folding, Folding funnel, Anfinsen’s experiment
- Lecture 13: Protein-ligand interactions
- Lecture 14: Allosteric regulation of proteins, e.g. haemoglobin
- Lecture 15: Membrane proteins
- Lecture 16: Introduction to enzymes
- Lecture 17: Theory of enzyme catalysis
- Lecture 18: Specificity of enzymes, e.g. Chymotrypsin
- Lecture 19: Enzyme inhibition. Types and mechanism of inhibitors. Design of inhibitors.
- Lecture 20: Engineered enzymes and their applications
- Lecture 21: Introduction to cells
- Lecture 22: Visualizing cells
- Lecture 23: Cell division cycle
- Lecture 24: Stem Cells
- Lecture 25: Cancer
- Lecture 26: Overview of the development of multicellular organization
- Lecture 27: Pattern formation and growth
- Lecture 28: Cell division, cell death and tissue homeostasis
- Lecture 29: Cell Junctions and extracellular matrix
- Lecture 30: Introduction to Neuron and the action potential
- Lecture 31: Vitamins and introduction to bioenergetics
- Lecture 32: Glycolysis, Gluconeogenesis and PPP
- Lecture 33: Citric Acid Cycle and Oxidative Phosphorylation
- Lecture 34: Photosynthesis
- Lecture 35: Photosynthetic carbohydrate synthesis
- Lecture 36: Evolution of life on earth
- Lecture 37: Protein evolution
- Lecture 38: Mechanisms of evolution
- Lecture 39: Evolution of eye
- Lecture 40: Model orgamisms
- Lecture 41: Introduction to microbial world and infectious diseases
- Lecture 42: Cell organization and unique features of bacteria
- Lecture 43: Understanding viruses - the smallest enemy
- Lecture 44: Pathogenicity and infection
- Lecture 45: Antibacterial and Antiviral Drugs
- Lecture 46: Introduction to the immune system
- Lecture 47: Innate immunity: the first lines of defense
- Lecture 48: Adaptive immune response
- Lecture 49: Antibody- structure, function and diversity
- Lecture 50: Vaccines and immunotherapy
- Lecture 51: Visualizing and analyzing nucleic acids: Gel electrophoresis and PCR
- Lecture 52: Visualizing and analyzing nucleic acids: DNA Sequencing
- Lecture 53: Overview of genetic engineering and its impact on society
- Lecture 54: Genetic engineering: Methods and applications
- Lecture 55: Cloning and Gene manipulation
- Lecture 56: Characterization methods
- Lecture 57: Chromatographic methods
- Lecture 58: protein - ligand interactions
- Lecture 59: Immunoassay techniques
- Lecture 60: Landmark experiments in biology
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- Live Session 19-03-2025
- Live Session 16-04-2025