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Course10210534266 lectures

Pharmacognosy & Metabolic Engineering

Prof. Adinpunya Mitra · IIT Kharagpur

Start with lecture 1 At NPTEL

Lectures

week-01

  1. Lecture 01: Pharmacognosy & Medicinal Plants Video
  2. Lecture 02:Plant Specialized Metabolites: Waste Products or Ecochemicals? Video
  3. Lecture 03: Evolution of Specialized Metabolism from Primary Metabolism Video
  4. Lecture 04: Production of specialized metabolites through cell and organ culture Video
  5. Lecture 05:Eliciting specialized metabolism in culture Video

week-02

  1. Lecture 6: Analysis of Specialized Metabolites – Tools and Techniques Video
  2. Lecture 7:Metabolic phytochemistry-based approaches for studying plant specialized metabolism Video
  3. Lecture 8: Metabolic engineering strategies in plants Video
  4. Lecture 9: Plant genetic transformation (through natural genetic engineer) Video
  5. Lecture 10: Design of vectors for Agrobacterium-mediated gene transfer; Transformed and co-...... Video

week-03

  1. Lecture 11: Introduction to alkaloids Video
  2. Lecrture 12: Biosynthesis of tropane alkaloids Video
  3. Lecrure 13: Engineering tropane alkaloid pathways in plants - I Video
  4. Lecture 14:Engineering tropane alkaloid pathway in plants – IIEngineering tropane alkaloid pathway.. Video
  5. Lecture 15: Isoquinoline alkaloids – biosynthesis and tissue localization Video

week-04

  1. Lecture 16:Isoquinoline alkaloids – late steps of biosynthetic pathway & tissue localization Video
  2. Lecture 17:Benzylisoquinoline alkaloids – Induced top1 mutant & natural T mutantEngineering.... Video
  3. Lecgture 18:Benzylisoquinoline alkaloids – Metabolic pathway engineering Video
  4. Lecture 19: RNAi-mediated replacement of morphine with nornarcotic alkaloid reticuline in opium.. Video
  5. Lecture 20:Isoquinoline alkaloids – biosynthesis and tissue localization Video

week-05

  1. Lecture 21:Indole alkaloids – Early steps of biosynthesis Video
  2. Lecture 22:Indole alkaloids – Metabolic engineering of early steps of indole alkaloid pathway Video
  3. Lecture 23:Indole alkaloids – Environmental factors regulating indole alkaloid biosynthesis Video
  4. Lecture 24:Indole alkaloids – Role of elicitors in modulating alkaloids accumulation Video
  5. Lecture 25:Indole alkaloids – Late steps of indole alkaloid biosynthesis Video
  6. Lecture 26: Indole alkaloids – Regulatory roles of transcription factors in light-induced...... Video

week-06

  1. Lecture 27:Engineering indole alkaloid pathways in Catharanthus roseus hairy root cultures Video
  2. Lecture 28:Missing enzymes of vindoline biosynthetic pathway Video
  3. Lecture 29:Monoterpene indole alkaloid pathway cell and tissue localization Video
  4. Lecture 30: Model for biosynthesis and secretion of monoterpenoid indole alkaloids involving.... Video
  5. Lecture 31:Metabolic reprogramming of periwinkle plant culture Video

week-07

  1. Lecture 32: Engineered yeast brews precursors of anticancer drug vinblastine Video
  2. Lecture 33: Recent discovery of strychnine biosynthetic pathway Video
  3. Lecture 34: Indole alkaloid biosynthesis – a final overview Video
  4. Lecture 35: Recent discovery of colchicine biosynthetic pathway Video

week-08

  1. Lecture 36: Biosynthesis of terpenoids – an outline Video
  2. Lecture 37: Diversity of monoterpenoids Video
  3. Lecture 38: Biosynthesis of monoterpenoids Video
  4. Lecture 39: Diversity of sesquiterpenes, diterpenes, triterpenes and polyterpenes Video
  5. Lecture 40: Oleoresins and polyterpenes – an outline Video
  6. Lecture 41: Monoterpenoids as components of floral scent volatiles: Metabolic engineering of...... Video

week-09

  1. Lecture 42: Biosynthesis of carotenoids and carotenoid cleavage products Video
  2. Lecture 43: Metabolic engineering of carotenoid pathway Video
  3. Lecture 44: Metabolic engineering of carotenoid pathway: Golden Rice Story Video
  4. Lecture 45: Menthol story: Biosynthesis and pathway manipulation I Video
  5. Lecture 46: Menthol story: Biosynthesis and pathway manipulation II Video
  6. Lecture 47: Artemisinin, hyperforin and taxol – three promising candidates for biotechnological... Video

week-10

  1. Lecture 48:Phenolics: Origin via shikimate pathway Video
  2. Lecture 49:Phenolics: Phenylpropanoids, benzenoids, coumarins, tannins Video
  3. Lecture 50: Phenolics: Monolignols, lignins and lignans Video
  4. Lecture 51: Phenolics: Metabolic engineering of monolignol pathways Video
  5. Lecture 52: Phenolics: Biosynthesis of lignans & podophyllotoxin; Caffeic acid esters... Video

week-11

  1. Lecture 53: Phenolics: Flavonoids, Flavones, Isoflavonoids, Proanthocyanidins Video
  2. Lecture 54: Phenolics: Biosynthesis of anthocyanins; Metabolic pathway engineering for enhance.... Video
  3. Lecture 55: Phenolics: Metabolic engineering of anthocyanin pathways in flowers Video
  4. Lecture 56: Phenolics: Alcohol acetyl transferses and volatile phenolics Video
  5. Lecture 57: Phenolics: Biosynthesis of volatile benzenoids Video

week-12

  1. Lecture 58: Phenolics: Biosynthesis of vanillin in plants Video
  2. Lecture 59: Phenolics: Metabolic engineering for vanillin Video
  3. Lecture 60: Phenolics: Biosynthesis of shikonin Video
  4. Lecture 61: Phenolics: Metabolic engineering of shikonin pathway Video
  5. Lecture 62: Molecular Pharming: Transplastomic plants Video
  6. Lecture 63: Molecular Pharming: production of human somatotropin in tobacco Video

Live Session

  1. Live Session 29-02-2024 Video
  2. Live Session 12-04-2024 Video
  3. Live Session 04-03-2025 Video

Syllabus and materials

At NPTEL, as the course publishes them.

Credits and licence

Institution
IIT Kharagpur
Department
Biotechnology
Teacher
Prof. Adinpunya Mitra
Level
Undergraduate
Language
English
Subjects
Biology
Source
NPTEL
Licence
CC BY-NC-SA, as NPTEL states it. Non-commercial use only. NPTEL's terms
Attribution
NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge.
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