Course10210505860 lectures
Industrial Biotechnology
Prof. Debabrata Das · IIT Kharagpur
About
The course aims to provide fundamental insights to exploit enzymes and microbes for the manufacturing of products which have a huge industrial significance. It uniquely blends the science and engineering with various biochemical processes to obtain products of diverse fields such as chemicals, food, bioenergy etc. The course introduces bioreactors, its types, operation methods and provides an experimental demonstration of the same. Strategies to obtain higher yields, design of the reactors and production of biofuels from microbes are thoroughly explained. Students of various disciplines such as biotechnology, chemical engineering, food engineering, and pharmaceutical industries can be benefitted from the course as it discusses the existing bioprocess applications such as wine and cheese making, antibiotics and vaccines etc. The course majorly focusses on the applications and allows students to gain practical knowledge rather than mere theory. Major bottlenecks for the operation of biochemical industries will be discussed.
Intended audience: BiotechnologyChemical EngineeringBiochemical EngineeringFood TechnologyEnvironmental EngineeringApplied MicrobiologyPharmacy.
Prerequisites: Knowledge in microbiology Biochemistry and mathematics in 10+2 level
Lectures
Week 1
- Lecture 1: Introduction
- Lecture 2: Development of industrial strain
- Lecture 3: Medium characteristics and biochemical pathways
- Lecture 4: Chemical reaction kinetics
- Lecture 5: Chemical reaction analysis (continued)
Week 2
- Lecture 6 : Different types of reactors
- Lecture 7: Reactor analysis
- Lecture 8 : Reactor analysis (continued)
- Lecture 9 : Stoichiometry of bioprocesses
- Lecture 10 : Stoichiometry of bioprocesses (continued)
Week 3
- Lecture 11: Enzymatic reaction Kinetics
- Lecture 12 : Enzymatic reaction Kinetics (continued)
- Lecture 13 : Immobilization techniques
- Lecture 14 : Life cycle of the microbial cell, Microbial growth kinetics, product formation and substrate degradation
- Lecture 15 : Life cycle of the microbial cell, Microbial growth kinetics, product formation and substrate degradation(continued)
Week 4
- Lecture 16: Life cycle of the microbial cell, Microbial growth kinetics(Contd.)
- Lecture 17: Overview of the fermenter
- Lecture 18: Flow diagrams and pumps and values used in fermentation industries
- Lecture 19: Upstream processing: Air sterilizer
- Lecture 20: Upstream processing:Medium sterilizer
Week 5
- Lecture 21 : Upstream Processing : Medium Sterilizer (Contd.)
- Lecture 22 : Downstream Processing : Solid - Liquid Separators
- Lecture 23 : Downstream Processing : Evaporator, Crystallizer
- Lecture 24 : Downstream Processing : Liquid - Liquid Extraction
- Lecture 25 : Ethanol Fermentation
Week 6
- Lecture 26 : Ethanol fermentation (continued)
- Lecture 27 : Brewing industry
- Lecture 28 : Brewing industry (continued)
- Lecture 29 : Wine industry
- Lecture 30 : Vinegar Production
Week 7
- Lecture 31 : Citric acid production
- Lecture 32 : Citric acid production (continued)
- Lecture 33 : Citric acid production (continued)
- Lecture 34 : Lactic acid production
- Lecture 35 : Lactic acid production (continued)
Week 8
- Lecture 36: Glutamic Acid Production
- Lecture 37: Penicillin Production
- Lecture 38: Penicillin Production (Contd.)
- Lecture 39: Streptomycin Production
- Lecture 40: Baker's Yeast fermentation
Week 9
- Lecture 41 : Baker's Yeast Fermentation (Contd.)
- Lecture 42 : Fodder Yeast Production
- Lecture 43 : Spirulina Production
- Lecture 44 : Alpha Amylase Production
- Lecture 45 : High Fructose Corn Syrup Production
Week 10
- Lecture 46 : Metal Leaching
- Lecture 47 : Cheese Production
- Lecture 48 : Cheese Production (Contd.)
- Lecture 49 : Biodiesel Production
- Lecture 50 : Butanol Production
Week 11
- Lecture 51: Biopesticides
- Lecture 52: Biopolymer
- Lecture 53: Hepatitis B Vaccine
- Lecture 54: Insulin
- Lecture 55: Biofertilizer
Week 12
- Lecture 56 : Aerobic effluent treatment process
- Lecture 57 : Anaerobic effluent treatment process: Biomethanation process
- Lecture 58 : Anaerobic effluent treatment process: Biomethanation process (continued)
- Lecture 59 : 10 m3 Pilot Plant operation for Biohydrogen production
- Lecture 60 : Summary and Conclusion of the Industrial Biotechnology Course
Syllabus and materials
At NPTEL, as the course publishes them.
Credits and licence
- Institution
- IIT Kharagpur
- Department
- Biotechnology
- Teacher
- Prof. Debabrata Das
- Level
- Undergraduate
- Language
- English
- Subjects
- Biology
- Source
- NPTEL
- Licence
- CC BY-NC-SA, as NPTEL states it. Non-commercial use only. NPTEL's terms
- Attribution
- NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge.
- Who can watch
- NPTEL gives no rating. Invisible Network shows it to Tweens profiles and older, judged from what the source says about it. How courses are placed