Podcasts · Science · Health & Fitness

This Week in Virology

Vincent Racaniello

99 episodes

This Week in Virology is a netcast about viruses - the kind that make you sick.

Episodes page 2 of 2

  1. TWiV 1323: One influenza infection, two patients

    · 1 h 49 min · Episode 1323

    TWiV explains mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines, and how toll-like receptor 7 alters the maternal immune landscape during influenza A infection to increase maternal and fetal morbidity, Hosts:…

  2. TWiV 1322: Clinical update with Dr. Daniel Griffin - Hantavirus special

    · 53 min · Episode 1322

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello reviewed the latest developments surrounding the hantavirus outbreak, including new interim guidance from the Centers for Disease Control and…

  3. TWiV 1321: Phage cross talk and cross reactions

    · 1 h 52 min · Episode 1321

    TWiV explains how cross-reactive anti-prophage antibodies and bacterial heteroresistance is implicated in phage therapeutic failure, and how phages communicate across species to shape microbial ecosystems. Hosts:…

  4. TWiV 1320: Clinical update with Dr. Daniel Griffin

    · 44 min · Episode 1320

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the outbreak of Hantavirus on a cruise ship and its potential for person-person transmission, how cessation of funding for global health by the…

  5. TWiV 1319: An earful of SARS-CoV-2

    · 1 h 44 min · Episode 1319

    TWiV explains the emergence of vaccine-derived poliovirus strains from the novel oral polio vaccine in the Central African Republic, and the infection of spiral ganglion neurons in the inner ear by SARS-CoV-2, which…

  6. TWiV 1318: Clinical update with Dr. Daniel Griffin

    · 1 h 09 min · Episode 1318

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello note the uncertain future of the National Science Foundation amid shifting U.S. funding priorities and governance; the rise of China as a global…

  7. TWiV 1317: Dead shrimp walking

    · 1 h 42 min · Episode 1317

    TWiV explains a study showing that viral DNA load in blood and saliva varied markedly with age, time of day season, sex, and depended on dozens of genetic loci, and identification of an emerging human eye disease…

  8. TWiV 1316: Clinical update with Dr. Daniel Griffin

    · 53 min · Episode 1316

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello are distressed by RFK Jr’s testimony in front of Congress, surges in rotavirus infections and the staggering number of people who believe in unproven…

  9. TWiV 1315: Jabs for bats

    · 1 h 50 min · Episode 1315

    TWiV explains a study showing that the wildlife trade, including live-animal markets, is a major driver of animal-to-human pathogen transmission, and ecological vaccination, a strategy to prevent zoonotic spillover…

  10. TWiV 1314: Clinical update with Dr. Daniel Griffin

    · 47 min · Episode 1314

    TWiV 1314: Clinical update with Dr. Daniel Griffin April 17, 2026 In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed but not surprised by poll results suggesting most Americans doubt…

  11. TWiV 1313: Maybe they're all dementia vaccines

    · 1 h 56 min · Episode 1313

    TWiV reviews evidence that influenza standard and high-dose vaccines reduce risk of Alzheimer’s dementia, and spread of deltaviruses by a viral Trojan horse mechanism. Hosts: Vincent Racaniello, Alan Dove, and Rich…

  12. TWiV 1312: Clinical update with Dr. Daniel Griffin

    · 45 min · Episode 1312

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello are aghast at the CDC’s decision to no longer test for rabies and mpox and the revised charter for its the advisory committee on immunization practices,…

  13. TWiV 1311: Jayhawks go viral

    · 1 h 33 min · Episode 1311

    Vincent visits the University of Kansas and speaks with Tony Fehr, Robin Orozco, Juergen Richt and Rob Unckless about their careers and the research ongoing in their laboratories. Host: Vincent Racaniello Guests:…

  14. TWiV 1310: Clinical update with Dr. Daniel Griffin

    · 40 min · Episode 1310

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello cover if the “five-second” rule for things that fall on the floor apply to surgical equipment, an outbreak of E. coli illness caused by raw cheese…

  15. TWiV 1309: Maybe they're all cancer vaccines

    · 1 h 46 min · Episode 1309

    TWiV explains why human papillomavirus vaccine-induced immunity can block infection, unlike all other vaccines, and how respiratory viral infections such as COVID and influenza prime accelerated lung cancer growth.…

  16. TWiV 1308: Clinical update with Dr. Daniel Griffin

    · 51 min · Episode 1308

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the resignation of a member of the advisory committee for immunization practices and the irony of his rationale that a judge slandered him,…

  17. TWiV 1307: My heart breaks for flu

    · 1 h 53 min · Episode 1307

    TWiV reviews the structural basis for Rep-mediated adeno-associated virus DNA genome packaging, how influenza virus-infected myeloid cells travel to the heart and infect cardiomyocytes, leading to IFN-fueled heart…

  18. TWiV 1306: Clinical update with Dr. Daniel Griffin

    · 44 min · Episode 1306

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello chat about death of water fowl on Long Island, ‘renaming’ of the FDA adverse event monitoring system, lawsuits against RFK Jr and HHS for illegal…

  19. TWiV 1305: Lab leak idea called on the carpet

    · 1 h 48 min · Episode 1305

    TWiV introduces sunshine virus of carpet pythons and its effect snakes after experimental infection, and development of a new tool to distinguish between naturally ocurring outbreaks and those that arise from lab…

  20. TWiV 1304: Clinical update with Dr. Daniel Griffin

    · 52 min · Episode 1304

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the global spread of the ‘eradicated’ poliovirus, the suggestion of RFK’s autocratic ability to change vaccine policy and the ‘resignation’ for…

  21. TWiV 1303: Overachieving vaccines

    · 1 h 51 min · Episode 1303

    TWiV reviews an association between shingles vaccination and slower biological aging, and how mucosal immunization in mice provides protection against disease caused by diverse viruses and bacteria. Hosts: Vincent…

  22. TWiV 1302: Clinical update with Dr. Daniel Griffin

    · 45 min · Episode 1302

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the health misconceptions that RFK Jr continues to perpetuate and how to combat them, first cases of highly pathogenic influenza in the…

  23. TWiV 1301: Lost in giant virus translation

    · 2 h 05 min · Episode 1301

    TWiV reviews lymphocytic choriomeningitis virus seroprevalence among urban pregnant women and newborns in Philadelphia, and a functional translation initiation complex encoded in the genome of giant viruses that drives…

  24. TWiV 1300: Clinical update with Dr. Daniel Griffin

    · 41 min · Episode 1300

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss several states and the governor of Pennsylvania suing HHS over changes in the childhood vaccination schedule, the vaccine derived type 2…

  25. TWiV 1299: Moth balls and blood clots

    · 1 h 46 min · Episode 1299

    TWiV explains how vaccine-induced thrombotic thrombocytopenia develops from antibodies to adenovirus and somatic hypermutation, and castration by a viral protein tyrosine phosphatase that targets a host cell cycle…

  26. TWiV 1298: Clinical update with Dr. Daniel Griffin

    · 43 min · Episode 1298

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss reversal of last week’s no review decision on a flu mRNA vaccine by Vinjay Prasad, appointment of Jay Bhattacharya as CDC director, no…

  27. TWiV 1297: Spillover squirrel

    · 1 h 49 min · Episode 1297

    TWiV explains the observation that filamentous virions act as non-infectious interfering particles to modulate papillomavirus infection, and transmission of monkeypox virus from fire-footed rope squirrels to sooty…

  28. TWiV 1296: Clinical update with Dr. Daniel Griffin

    · 47 min · Episode 1296

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello are shocked by recent events, including Dr. Oz’s appeal for measles vaccination, Vinjay Prasad’s unilateral rejection of Moderna’s mRNA influenza…

  29. TWiV 1295: Are YOU willing to take one for the team?

    · 1 h 50 min · Episode 1295

    TWiV reviews a survey conducted in Cambodia's floating villages to explore measles vaccination perceptions and willingness to consider novel vaccination approaches, and how a prophage defends against an infecting…

  30. TWiV 1294: Clinical update with Dr. Daniel Griffin

    · 57 min · Episode 1294

    In his weekly clinical update during Ground hog week, Dr. Griffin and Vincent Racaniello are back to discuss the measles outbreak in South Carolina, American Academy of Pediatrics vaccine recommendations and shingles…

  31. TWiV 1293: The enemy of your parasite is your friend

    · 1 h 47 min · Episode 1293

    TWiV reviews the finding in Sweden that immunization against cervical cancer with human papillomavirus vaccine also protects the non-immunized, and methyl salicylic acid as a key volatile molecule that attracts…

  32. TWiV 1292: Clinical update with Dr. Daniel Griffin

    · 45 min · Episode 1292

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss with disgust the decline and fall of American public health and the rise of “only me” when highlighting completion of the US withdrawal from the…

  33. TWiV 1291: A foot in the door for cytomegalovirus

    · 1 h 58 min · Episode 1291

    TWiV explains emergence of a neurovirulent double recombinant from the ‘improved’ nOPV2 in Uganda, and efficiency of viral entry determined whether cells are latently or lytically infected with cytomegalovirus. Hosts:…

  34. TWiV 1290: Clinical update with Dr. Daniel Griffin

    · 57 min · Episode 1290

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss screwworm, how the shingles vaccination slows biological aging (for all of you who want to reset ‘the clock’ and live forever…..you know who you…

  35. TWiV 1289: Building a better hepatitis B trap

    · 1 h 42 min · Episode 1289

    TWiV explains how the dengue virus protein NS1 alters Aedes aegypti midgut permeability and favors virus dissemination, and achieving a complete hepatitis B virus cure in chronic hepatitis B virus-infected humanized…

  36. TWiV 1288: Clinical update with Dr. Daniel Griffin

    · 45 min · Episode 1288

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr’s announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the…

  37. TWiV 1287: Ancient herpesviruses and modern dementia

    · 1 h 45 min · Episode 1287

    TWiV explain the tracing of 2500 years of human betaherpesvirus 6A and 6B diversity through ancient human DNA, the effect of shingles vaccination at different stages of the dementia disease course. Hosts: Vincent…

  38. TWiV 1286: Clinical update with Dr. Daniel Griffin

    · 43 min · Episode 1286

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr’s announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the…

  39. TWiV 1285: Encapsidating viruses 2025

    · 1 h 48 min · Episode 1285

    TWiV reviews compelling virology themes for 2024, as heard in our 98 episodes, including 22 guests. Hosts: Vincent Racaniello and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV!…

  40. TWiV 1284: Clinical update with Dr. Daniel Griffin

    · 30 min · Episode 1284

    Recording after the ball drops, Dr. Griffin and Vincent Racaniello wish everyone a Happy New Year, discuss an evidence-based approach to teaching and practice medicine and reminisce on the history of vaccine…

  41. TWiV 1273: Myocarditis and mimicry

    · 1 h 58 min · Episode 1283

    TWiV explains studies which reveal that Inhibition of CXCL10 and IFN-γ mitgates myocarditis associated with SARS-CoV-2 mRNA vaccination, and identification of a bacteriophage T7 protein that antagonizes the DNA…

  42. TWiV 1282: Clinical update with Dr. Daniel Griffin

    · 43 min · Episode 1282

    Calling out “Happy Christmas to all and to all a good-night, Dr. Griffin and Vincent Racaniello discuss high path influenza in dairy herds in Wisconsin and Marburg virus in Ethiopia before Dr. Griffin then deep dives…

  43. TWiV 1281: Sex, herpes, and plankton

    · 1 h 23 min · Episode 1281

    Vincent travels to Tegernsee, Germany for the Sixth Ringberg Symposium on Giant Viruses, where he talks with John Archibald, Susana Coelho, and Tom Delmont about their work on – you guessed it – giant viruses. Host:…

  44. TWiV 1280: Clinical update with Dr. Daniel Griffin

    · 37 min · Episode 1280

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello protest Vinjay Prasad, head of CBER FDA Nov memo stating administration of the COVID-19 vaccine resulted in 10 children’s deaths, but are cautiously…

  45. TWiV 1279: Let hepatitis b

    · 1 h 45 min · Episode 1279

    TWiV reviews considerations and perspectives on phage therapy, and the Nobel Prize-winning discovery of hepatitis b virus. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Jolene Ramsey Subscribe (free): Apple…

  46. TWiV 1278: Clinical update with Dr. Daniel Griffin

    · 50 min · Episode 1278

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the rise in norovirus infections, contamination of infant formula and botulism outbreak, confusion and response to the CDC’s ACIP decision to…

  47. TWiV 1277: Vaccine talk with Jake Scott

    · 1 h 39 min · Episode 1277

    Infectious diseases physician Jake Scott returns to TWiV to discuss the dangerous anti-vaccine policies being established in the US and what RFK Jr. and his associates get wrong. Hosts: Vincent Racaniello, Rich…

  48. TWiV 1276: Clinical update with Dr. Daniel Griffin

    · 55 min · Episode 1276

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the positive side effect of the shingles vaccine on dementia outcomes and how one dose of the HPV vaccine is non-inferior to two doses, but are…

  49. TWiV 1275: An amazing sequence and a gutsy therapy

    · 1 h 49 min · Episode 1275

    TWiV explains the Nobel Prize-winning discovery of pre-mRNA splicing, and engineering bacteriophage to deliver proteins to the human intestine. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Subscribe…

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