Podcasts · Science · Health & Fitness

This Week in Virology

Vincent Racaniello

99 episodes

This Week in Virology is a netcast about viruses - the kind that make you sick.

Episodes page 1 of 2

  1. TWiV 1369: Florida Model Makes Measles Great Again

    · 1 h 57 min · Episode 1369

    TWiV explains projected effects of removing school-entry vaccination requirements on measles transmission in Florida and evidence that HLA class I escape drives the evolution of SARS-CoV-2 in human populations. Hosts:…

  2. TWiV 1368: Clinical Update with Dr. Daniel Griffin

    · 55 min · Episode 1368

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are discouraged by the continuous attack on vaccines especially the birth dose of the hepatitis B virus vaccine, effects of the 2026 changes in…

  3. TWiV 1367: Turning Off Hepatitis B Virus Without Cutting its DNA

    · 1 h 53 min

    TWiV explains a study which shows that influenza A virus infection induces immune dysregulation in the placenta and fetus without vertical transmission in nonhuman primates, and development of an epigenetic silencer…

  4. TWiV 1366: Clinical Update with Dr. Daniel Griffin

    · 1 h 02 min · Episode 1366

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are crestfallen to learn of the 6th measles death in Pennsylvania and more than 9000 deaths from Ebola, an enterovirus/Coxsackievirus outbreak at the…

  5. TWiV 1365: Andes Virus Up Close

    · 57 min · Episode 1365

    TWiV travels to Porto, Portugal for the annual meeting of the European Society for Clinical Virology, where he speaks with Catherine and Corinne about their work on the Andes virus outbreak on the MV Hondius. Host:…

  6. TWiV 1364: Clinical Update with Dr. Daniel Griffin

    · 1 h 14 min · Episode 1364

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss their continuing struggle to understand the ongoing outbreak of cyclospora, decimation of US public health including 30% or greater loss of…

  7. TWiV 1363: A Cauldron of Bats

    · 1 h 54 min · Episode 1363

    TWiV explains a study testing how 16 hypothesized social and environmental drivers impact disease outbreaks, concluding that infectious disease spillover and emergence are multi-causal, and that no one-size-fits-all…

  8. TWiV 1362: Clinical Update with Dr. Daniel Griffin

    · 54 min · Episode 1362

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello continue their ongoing exasperation over 5 deaths in Pennsylvania associated with measles infections, the absurdity of RFK Jr.’s statement that AI is…

  9. TWiV 1361: Ancient Viral Sword and Shield

    · 1 h 46 min · Episode 1361

    TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer’s Disease…

  10. TWiV 1360: Clinical Update with Dr. Daniel Griffin

    · 1 h 00 min · Episode 1360

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello frustration continues over the increasing number of measles infections, Kennedy’s undermining of vaccines, perpetuation of autism- vaccine,…

  11. TWiV 1359: SSPE, the Long Shadow of Measles

    · 1 h 10 min · Episode 1359

    Roberto Cattaneo and Kalpana Yadav join TWiV at the 2026 meeting of the American Society for Virology to discuss how the absence of measles virus receptors in the brain selects for hyperfusogenic variants that spread…

  12. TWiV 1358: Clinical Update with Dr. Daniel Griffin

    · 54 min · Episode 1358

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are angered by the continuous reporting of measles deaths in the US and around the world, the Ebola outbreak in Uganda, changes in reporting of virus…

  13. TWiV 1357: Furin, Naturally with Paul Bieniasz

    · 1 h 44 min · Episode 1357

    Paul Bieniasz joins TWiV to discuss his lab’s discovery that the coronavirus nuclease NSP15 cuts viral RNA into oligonucleotides that are reinserted elsewhere in the viral RNA, generating insertion mutations at a…

  14. TWiV 1356: Clinical update with Dr. Daniel Griffin

    · 47 min · Episode 1356

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello delve into dengue virus infections in Florida, recent human rabies infections in the US, proposed changes in biomedical funding including…

  15. TWiV 1355: Four billion years of AI training data

    · 1 h 38 min · Episode 1355

    TWiV reviews a landmark paper reporting the first generative design of complete viral genomes using AI, producing 16 viable bacteriophages that overcame antibiotic-resistant bacteria where natural phages could not, and…

  16. TWiV 1354: Clinical update with Dr. Daniel Griffin

    · 1 h 05 min · Episode 1354

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello remember Dolly Parton and her patronage of science, especially development of the COVID-19 vaccines, if the shingles vaccine protect against…

  17. TWiV 1353: Phage bet-hedging and EBV antibodies

    · 1 h 52 min · Episode 1353

    TWiV explores how bacteriophages enable bet-hedge against bacterial immune defenses, and how transgenic mice engineered to produce human antibodies yielded potent anti-EBV candidates targeting gp350 and gp42, a…

  18. TWiV 1352: Clinical update with Dr. Daniel Griffin

    · 49 min · Episode 1352

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are disheartened by the suggested change in federal vaccine recommendations, how Florida rolled back 4 childhood vaccine school requirements, results…

  19. TWiV 1351: Ebola Virus Brains and Contagious Catfish Cancers

    · 1 h 41 min · Episode 1351

    TWiV describes a human cerebral organoid model for Ebola virus persistence, and brown bullhead catfish melanoma, a novel transmissible cancer. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free):…

  20. TWiV 1350: Clinical update with Dr. Daniel Griffin

    · 1 h 01 min · Episode 1350

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are perplexed by the state of global public health as malaria, cholera and other infectious diseases are spread by civil warfare, the lack of…

  21. TWiV 1349: Smallpox and mummies

    · 2 h 03 min · Episode 1349

    TWiV explains how liquid–liquid phase separation and a phage-encoded inhibitor cooperatively drive transcriptional transition during phage SPO1 infection, and the first smallpox virus genomes from an early outbreak in…

  22. TWiV 1348: Clinical update with Dr. Daniel Griffin

    · 55 min · Episode 1348

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are troubled by the latest executive order changing routine childhood vaccine recommendations, the call for nominations to join the Advisory…

  23. TWiV 1347: No Short Answers for Long COVID

    · 1 h 47 min · Episode 1347

    TWiV explains research showing that Long COVID is associated with reactivation of numerous chronic viruses, including herpesviruses and anelloviruses, and with the production of autoantibodies that target neurological…

  24. TWiV 1346: Clinical update with Dr. Daniel Griffin

    · 54 min · Episode 1346

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by Erica Schwartz’ confirmation as CDC director, the GAO proposed pandemic preparedness plans, the national cyclospora outbreak and…

  25. TWiV 1345: Rocky Mountain Virology High

    · 1 h 18 min · Episode 1345

    TWiV travels to Colorado State University in Ft. Collins, where he speaks with Angela Bosco-Lauth, Rebekah Kading, and Mark Stenglein about their careers and their virology research. Host: Vincent Racaniello Guests:…

  26. TWiV 1344: Clinical update with Dr. Daniel Griffin

    · 49 min · Episode 1344

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the numerous attempts by states to roll back vaccine laws, the recent surge of Dengue virus cases in Sri Lanka, the national cyclospora…

  27. TWiV 1343: Batting averages and stolen bases

    · 1 h 42 min · Episode 1343

    TWiV explains research which shows that Per os infectivity factors are essential for bracovirus infection and wasp parasitism, and that periodic shifts in viral load increase risk of Hendra virus spillover from…

  28. TWiV 1342: Clinical update with Dr. Daniel Griffin

    · 40 min · Episode 1342

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello explore the source/not source of the national cyclospora outbreak, trust in the FDA to correctly identify the source, new screwworm, Legionnaires and…

  29. TWiV 1341: Phage breaks and COVID origins

    · 1 h 40 min · Episode 1341

    TWiV explains research that reveals dual activity of a phage-encoded lysin that modulates infection dynamics in a mycobacteriophage, and refutes a proposed link between the SARS-CoV-2 furin cleavage site and…

  30. TWiV 1340: Clinical update with Dr. Daniel Griffin

    · 44 min · Episode 1340

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello debate if Senator Mitch McConnell’s recent hospitalization is due to post-polio syndrome or just old age, how air quality from Maine to Chicago has…

  31. TWiV 1339: Ebola up close with Tom Ksiazek

    · 1 h 51 min · Episode 1339

    Tom Ksiazek, a world-renowned virus expert with 40 years of experience on the front lines of some of the worst outbreaks the world has ever seen, joins TWiV to discuss his career, ebolaviruses in general, and the…

  32. TWiV 1338: Clinical update with Dr. Daniel Griffin

    · 43 min · Episode 1338

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are dismayed over the military deaths due to the voluntary influenza vaccination policy, FDA’s first vaccine recommendations since 2023, the efficacy…

  33. TWiV 1337: The whitefly and the Red Queen

    · 1 h 53 min · Episode 1337

    TWiV explains research that reveals an an alternative evolutionary path of antiviral signalling in a sea anemone, and how a bacterial symbiont and a plant virus enhance insect fitness by inducing physical defenses…

  34. TWiV 1336: Clinical update with Dr. Daniel Griffin

    · 23 min · Episode 1336

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello lament about the new ACIP charter, how administration of the HPV vaccine has eliminated cervical cancer deaths in young women, the global economic…

  35. TWiV Special: Albert Sabin with Karen Torghele

    · 1 h 10 min

    Vincent speaks with Karen Torghele about her recently published biography of polio vaccine pioneer Albert Sabin, the first ever written. Host: Vincent Racaniello Guest: Karen Torghele Subscribe (free): Apple…

  36. TWiV 1335: TldR, bacterial hot rods and nullifying norovirus

    · 1 h 56 min · Episode 1335

    TWiV explains research showing how temperate phages enhance bacterial host fitness via RNA-guided flagellar remodelling, and that IgA antibody is necessary and sufficient to prevent norovirus infection in mice. Hosts:…

  37. TWiV 1334: Clinical update with Dr. Daniel Griffin

    · 31 min · Episode 1334

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the global economic burden of infectious disease, restoring trust in vaccinology, the Legionnaires outbreak in Harlem, new screwworm cases,…

  38. TWiV 1333: STING like a nanoparticle, float like HIV

    · 1 h 55 min · Episode 1333

    TWiV explains research showing how HIV-1 signalling remodels nuclear pores to licence infection, and development of STING agonist nanoparticles to enable coordinated mucosal-systemic immunity for durable…

  39. TWiV Special: Ebola virus and Andes virus with John Dye

    · 57 min

    Vincent travels to ASM Microbe in Washington DC to speak with John Dye of the United States Army Medical Research Institute of Infectious Diseases about the recent outbreaks of Bundibugyo ebolavirus in Africa and Andes…

  40. TWiV 1332: Clinical update with Dr. Daniel Griffin

    · 54 min · Episode 1332

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello express concern about vaccine policy and ACIP, scaling back of the CDC’s role in global public health, shingles vaccine and dementia, new screwworm…

  41. TWiV 1331: A drug for cervical cancer

    · 1 h 58 min · Episode 1331

    TWiV explains research showing that dairy cows are infected with low doses of influenza A(H5N1) and do not transmit efficiently to other animals, and covalent inhibitors of human papillomavirus type 16 E6 protein that…

  42. TWiV 1330: Clinical update with Dr. Daniel Griffin

    · 1 h 11 min · Episode 1330

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast…

  43. TWiV 1329: How HIV-1 goes nuclear

    · 1 h 51 min · Episode 1329

    TWiV explains research showing limited transmission of cervid prions to nonhuman primates, and the finding that cone-shaped HIV-1 capsids are transported through intact nuclear pores. Hosts: Vincent Racaniello, Alan…

  44. TWiV 1328: Clinical update with Dr. Daniel Griffin

    · 1 h 01 min · Episode 1328

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast…

  45. TWiV 1327: Influenza viruses in the MIST

    · 2 h 00 min · Episode 1327

    TWiV explains research on human influenza virus transmission that reveals heterogeneous expulsion of infectious virus into air, and how gut bacteriophages dictate inflammation heterogeneity through tuning the…

  46. TWiV 1326: Clinical update with Dr. Daniel Griffin

    · 39 min · Episode 1326

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello comment on incidences of locally transmitted malaria in the US, mpox diagnostics, the latest developments surrounding hantavirus infections, and the…

  47. TWiV 1325: Sticky flu with Hannah Rowe

    · 57 min · Episode 1325

    Vincent travels to Oregon State University in Corvallis to meet up with Hannah Rowe to talk about her career and her work demonstrating how the interaction of influenza A virus and Streptococcus pneumonia influences…

  48. TWiV 1324: Clinical update with Dr. Daniel Griffin

    · 46 min · Episode 1324

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss withdrawal of the ACIP charter published in April 2026, the first council meeting on antibiotic resistant bacteria, the latest developments…

  49. TWiV 1323: One influenza infection, two patients

    · 1 h 49 min · Episode 1323

    TWiV explains mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines, and how toll-like receptor 7 alters the maternal immune landscape during influenza A infection to increase maternal and fetal morbidity, Hosts:…

  50. TWiV 1322: Clinical update with Dr. Daniel Griffin - Hantavirus special

    · 53 min · Episode 1322

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello reviewed the latest developments surrounding the hantavirus outbreak, including new interim guidance from the Centers for Disease Control and…

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