Podcasts · This Week in Virology
TWiV 1361: Ancient Viral Sword and Shield
· 1 h 46 min · Episode 1361
Episode TWiV 1361: Ancient Viral Sword and Shield
TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer’s Disease neuropathology evolved as a host defense response to microbial infection in the brain.
Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker
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Links for this episode
• Support science education at MicrobeTV • Bob Tesh dies (Galv News) • Comment on propsed changes to NIH peer review (NIH) • NIH peer review proposed changes (Forbes) • Ancient RNA guided DNA recognition (Science) • Noncontiguous geometric triplex (Science) • p-tau has anti-herpes virus activity (Nat Neurosci) • Letters read on TWiV 1361 • Timestamps by Jolene Ramsey. Thanks!
Picks of the Week
Brianne – APoD September 14: Origins of Elements Alan – Redshirts, by John Scalzi Vincent – Prone to Bruise by David Molesky he’s at Spring/Break till 9/28
Listener Pick
Anne – Nikon Small World in Motion Competition
Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
Content in this podcast should not be construed as medical advice.
Links in the notes 16
- https://en.wikipedia.org/wiki/Vincent_Racaniello
- https://bbarkerdrew.com/
- https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065
- https://www.microbe.tv/contribute
- https://www.galvnews.com/obituaries/dr-robert-bradfield-tesh/article_b359d365-682a-5e94-8ad7-e60b9109baa6.html
- https://rfi.grants.nih.gov/?s=6a2b1c22c3fcfda46e0badd2
- https://www.science.org/doi/10.1126/science.aei0498
- https://www.science.org/doi/10.1126/science.aei3472
- https://www.nature.com/articles/s41593-025-02157-0
- https://www.microbe.tv/twiv/twiv-1355-letters/
- https://ramseylab.vercel.app/
- https://apod.nasa.gov/apod/ap260914.html
- https://bookshop.org/p/books/redshirts-john-scalzi/e1cebcdce4d663fa
- https://moleskystudio.com/paintings
- https://www.springbreakartshow.com/
- https://www.nytimes.com/2026/09/16/science/microscopic-videos-invisble-nikon-small-world.html?unlocked_article_code=1.B1E.-AIK.tQXVUCC8LRSv&smid=em-share
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