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Course11210600271 lectures

Microfluidics and Microsystems

Prof. Ashis Kumar Sen · IIT Madras

Start with lecture 1 At NPTEL

About

This course offers a comprehensive foundation in microfluidics, covering the physics of fluid transport at the microscale, microfabrication methods, and the design of essential microfluidic components. Students will learn how surface forces, interfacial phenomena, and scaling laws fundamentally alter fluid behavior in miniaturized systems. The course integrates classical topics with emerging fields such as electrofluidics, acoustofluidics, and magnetofluidics. By the end, learners will gain the conceptual and practical knowledge required to understand, analyze, and design modern lab-on-chip and microscale flow systems.

Intended audience: M-Tech, MS and PhD students

Prerequisites: Mathematics, UG Fluid Mechanics

Lectures

Week 1

  1. Introduction to Microfluidics - Part 1 YouTube
  2. Introduction to Microfluidics - Part 2 YouTube
  3. Introduction to Microfluidics - Part 3 YouTube
  4. Flow features of Microfluidics YouTube
  5. Multi-physics phenomena in Microfluidics YouTube
  6. Scaling in Microfluidics: Introduction YouTube

Week 2

  1. Scaling in Microfluidics: Examples & Limitations YouTube
  2. Microfluidic device fabrication YouTube
  3. Different steps of Microfabrication YouTube
  4. Silicon crystallography & Miller indices YouTube
  5. Silicon wafer Processing: Cleaning, Oxidation , Photoresist coating, and Soft baking YouTube
  6. Silicon wafer Processing: UV exposure, Development, etching, and bonding YouTube

Week 3

  1. Overview of Doping and Oxidation YouTube
  2. Oxidation of Silicon wafer YouTube
  3. Thin film metallization YouTube
  4. Silicon micromachining YouTube
  5. Anisotropic Wet Etching YouTube
  6. Dry Etching and Bonding Techniques YouTube

Week 4

  1. Soft Lithography for Microfluidic devices YouTube
  2. Microfabrication & interconnections in Microfluidic devices YouTube
  3. Fundamentals of Microscale flows YouTube
  4. Continuum behaviour in microfluidics YouTube
  5. Gas flows & Microchannel flows in Microfluidics YouTube
  6. Pressure-Driven Microchannel Flows YouTube

Week 5

  1. Poiseuille flow in Microchannels YouTube
  2. Eigenfunction Solution of Rectangular Microchannel Poiseuille Flow YouTube
  3. Boundary conditions & slip phenomena in Microfluidic flows YouTube
  4. Low Reynolds number flows YouTube
  5. Time-dependent Couette flow:Part 1 YouTube
  6. Time-dependent Couette flow:Part 2 YouTube

Week 6

  1. Flow with two Length Scales YouTube
  2. Stokes Drag and Hydraulic Resistance in Microfluidic flow YouTube
  3. Channel Compliance and Hydraulic Capacitance YouTube
  4. Capillarity and Surface Tension YouTube
  5. Young - Laplace Pressure YouTube
  6. Consequence of Laplace Pressure YouTube

Week 7

  1. Contact Angle and Wetting Behavior: Wenzel Model YouTube
  2. Contact Angle and Wetting Behavior: Cassie-Baxter Model YouTube
  3. Fundamentals of Contact Angle Measurement YouTube
  4. Capillary Flows in Microfluidics YouTube
  5. Capillarity and Wetting in Microscale Flows YouTube
  6. Fundamentals of Surfactants and Wetting YouTube

Week 8

  1. Surfactants and Their Applications YouTube
  2. Measurement of Surface Tension:Part 1 YouTube
  3. Measurement of Surface Tension:Part 2 YouTube
  4. Instabilities in Fluids YouTube
  5. Rayleigh-Plateau Instability: Part 1 YouTube
  6. Rayleigh-Plateau Instability: Part 2 YouTube

Week 9

  1. Stability of Fluid Interfaces: Part 1 YouTube
  2. Fundamentals of EDL: Part 2 YouTube
  3. Introduction to Electrokinetics: Part 1 YouTube
  4. Introduction to Electrokinetics: Part 2 YouTube
  5. Fundamentals of EDL: Part 1 YouTube
  6. Stability of Fluid Interfaces: Part 2 YouTube

Week 10

  1. Electro-Osmosis in Parallel plate channels YouTube
  2. Electro-osmotic Pumping in Microchannels YouTube
  3. Fundamentals of Dielectrophoresis YouTube
  4. Dielectrophoresis of a Dielectric Sphere YouTube
  5. Dielectrophoretic Force and Particle Trapping in Microfluidic Channels YouTube
  6. AC Dielectrophoresis and Electrophoresis YouTube

Week 11

  1. Introduction to Magnetism YouTube
  2. Introduction to Magnetofluidics - Part 1 YouTube
  3. Introduction to Magnetofluidics - Part 2 YouTube
  4. Application of Magnetofluidics YouTube
  5. Introduction to Acoustofluidics YouTube
  6. First Order Perturbation Theory YouTube

Week 12

  1. Second Order Perturbation Theory & Acoustic streaming YouTube
  2. Acoustic resonance in viscous liquids YouTube
  3. Acoustic Radiation force on small particles Part 1 YouTube
  4. Acoustic Radiation force on small particles Part 2 YouTube
  5. Mixing in Microfluidics Part 1 YouTube

Syllabus and materials

At NPTEL, as the course publishes them.

Credits and licence

Institution
IIT Madras
Department
Mechanical Engineering
Teacher
Prof. Ashis Kumar Sen
Level
Graduate
Language
English
Subjects
Engineering
Source
NPTEL
Licence
CC BY-NC-SA, as NPTEL states it. Non-commercial use only. NPTEL's terms
Attribution
NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge.
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