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Course10410836366 lectures

One and Two dimensional NMR Spectroscopy: Concepts and Spectral Analysis

Prof. N Suryaprakash · IISc Bangalore

Start with lecture 1 At NPTEL

Lectures

Week 1 NMR Basics and Conceptual Understanding

  1. Lec 01 - Nuclear Spin Video
  2. Lec 02 - NMR spin physics-I Video
  3. Lec 03 - NMR spin physics-II Video
  4. Lec 04 - Energy levels and allowed transitions Video
  5. Lec 05 - Transitions in coupled spin systems Video

Week 2 NMR Interaction parameters

  1. Lec 06 - Interaction parameters Video
  2. Lec 07 - Chemical Shifts Video
  3. Lec 08 - Shielding and deshielding, ppm and frequency scales Video
  4. Lec 09 - Factors affecting the chemical shifts Video
  5. Lec 10 - Scalar couplings Video

Week 3 Scalar Couplings and Spectral Multiplicity

  1. Lec 11 Scalar couplings Video
  2. Lec 12 Coupling mechanism Video
  3. Lec 13 Splitting patterns Video
  4. Lec 14 Multiplicity patterns Video
  5. Lec 15 Analysis of multiplicity patterns Video

Week 4 Strong and Weakly coupled spins and Analysis of 1D Spectra

  1. Lec 16 Coupled spin system Video
  2. Lec 17 Nomenclature for coupled spins Video
  3. Lec 18 Energy levels of two and three coupled spins Video
  4. Lec 19 Analysis of 1H NMR spectra-I Video
  5. Lec 20 Analysis of 1H NMR spectra-II Video

Week 5 Analysis of Spectra of 1H and 13C

  1. Lec 21 Analysis of 1H NMR spectra-III Video
  2. Lec 22 Coupling of 1H with other nuclei-I Video
  3. Lec 23 Coupling of 1H with other nuclei-II Video
  4. Lec 24 13C-NMR-I Video
  5. Lec 25 13C-NMR-II Video

Week 6 Analysis of Heteronuclear Spectra

  1. Lec 26 13C-NMR-III Video
  2. Lec 27 13C-NMR-IV Video
  3. Lec 28 Analysis of 19F spectra Video
  4. Lec 29 31P NMR Video
  5. Lec 30 Analysis of spectra of Heteronuclei Video

Week 7 Spectral Analysis, spin echoes and sensitivity enhancement

  1. Lec 31 Heteronuclear spectral analysis Video
  2. Lec 32 Spin Echoes Video
  3. Lec 33 Spin Echoes-II Video
  4. Lec 34 Sensitivity enhancement Video
  5. Lec 35 Polarization transfer Video

Week 8 INEPT, 2D NMR and 2D-COSY

  1. Lec 36 INEPT Video
  2. Lec 37 2D NMR Video
  3. Lec 38 2D NMR-II Video
  4. Lec 39 2D-COSY-I Video
  5. Lec 40 2D COSY-II Video

Week 9 Variants of 2D-COSY, TOCSY and HSQC

  1. Lec 41 Types of COSY spectra Video
  2. Lec 42 TOCSY Video
  3. Lec 43 HSQC-I Video
  4. Lec 44 HSQC-II Video
  5. Lec 45 me-HSQC Video

Week 10 HSQC, HMBC, INADEQUATE

  1. Lec 46 HSQC and HMBC Video
  2. Lec 47 HMBC-II Video
  3. Lec 48 2D INADEQUATE Video
  4. Lec 49 2D-INADEQUATE and 2D J-Resolved Video
  5. Lec 50 Homo and Heteronuclear J-resolved Video

Week 11 NOE and ROE

  1. Lec 51 Conceptual understanding of NOE Video
  2. Lec 52 Positive and negative NOE Video
  3. Lec 53 NOE and correlation times Video
  4. Lec 54 Complications in NOE, Steady state NOE Video
  5. Lec 55 ROESY and Tr NOE Video

Week 12 2D experiments and molecular structure

  1. Lec 56 Combined utility of COSY, TOCSY, HSQC, NOESY Video
  2. Lec 57 Steady State NOE Video
  3. Lec 58 1D NOE, 1D TOCSY Video
  4. Lec 59 1D-TOCSY, PURESHIFT Video
  5. Lec 60 PURSHIFT NMR Video

Live Session

  1. Live Session 20-02-2024 Video
  2. Live Session 19-03-2024 Video
  3. Live Session 18-04-2024 Video
  4. Live Session 21-02-2025 Video
  5. Live Session 19-03-2025 Video
  6. Live Session 17-04-2025 Video

Syllabus and materials

At NPTEL, as the course publishes them.

Credits and licence

Institution
IISc Bangalore
Department
Chemistry and Biochemistry
Teacher
Prof. N Suryaprakash
Level
Undergraduate
Language
English
Subjects
Chemistry
Source
NPTEL
Licence
CC BY-NC-SA, as NPTEL states it. Non-commercial use only. NPTEL's terms
Attribution
NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge.
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