Learn · Organic Chemistry in Biology and Drug Development
Lecture 62 of 63Week 12 :
Lecture 62 : Pharmakinetics and pharmadynamics
Prof. Amit Basak · IIT Kharagpur
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All the lectures
- Lecture 01: A brief introduction to Molecules of Life: Structure of Amino acids and their various charged forms
- Lecture 02: Biological Macromolecules and Small molecules: Importance and functions
- Lecture 03: Amino Acids: The building block of proteins
- Lecture 04: Amino acids: separation and detection, Electrophoresis and Ninhydrin reaction
- Lecture 05 : Method of determination of Amino acid sequence: primary structure of polypeptide/protein
- Lecture 06 : Selective peptide bond cleavage: Enzymatic and Non-enzymatic methods
- Lecture 07 : Peptide synthesis: Protecting groups for amine and carboxyl functionality
- Lecture 08 : Peptide synthesis (continued): Protection, coupling and deprotection methods
- Lecture 09 : Recent development of coupling agents; Merrifield’s method of solid phase peptide synthesis
- Lecture 10 : Hierarchial structure of proteins: Secondary, tertiary and quaternary structure
- Lecture 11 : Ramachandran plot and protein purification techniques
- Lecture 12 : Protein purification techniques (continued)..
- Lecture 13 : Introduction to Enzymes and its kinetics
- Lecture 14 : Enzyme catalysed reactions and introduction to catalytic activity of proteases
- Lecture 15 : Enzyme Kinetics (Contd.)
- Lecture 16 : Concept of Enzyme Inhibition
- Lecture 17 : Concept of Enzyme Inhibition (Contd.)
- Lecture 18 : Problems on Enzyme Kinetics and Enzyme Inhibition
- Lecture 19 : Synthetic Biology
- Lecture 20 : Synthetic Biology (Contd.)
- Lecture 21 : Synthetic Biology (Contd.)
- Lecture 22 : Nucleic Acid
- Lecture 23 : Nucleic Acid (Contd.)
- Lecture 24 : DNA sequencing method
- Lecture 25 : DNA sequencing method (Contd.)
- Lecture 26 : DNA sequencing method (Contd.)
- Lecture 27 : Synthesis of oligonucleotide
- Lecture 28 : Central dogma: DNA replication, transcription and translation
- Lecture 29 : Central dogma: DNA replication, transcription and translation (Contd.)
- Lecture 30 : Central dogma: DNA replication, transcription and translation (Contd.)
- Lecture 31 : Central dogma: DNA replication, transcription and translation (Contd.)
- Lecture 32 : Central dogma: DNA replication, transcription and translation (Contd.)
- Lecture 33 : Molecular Biology
- Lecture 34 : Molecular Biology (Contd.)
- Lecture 35 : Chemistry of cofactors/coenzymes
- Lecture 36 : Chemistry of cofactors/coenzymes (Contd.)
- Lecture 37 : Chemistry of cofactors/coenzymes (Contd.)
- Lecture 38 : Chemistry of cofactors/coenzymes (Contd.)
- Lecture 39 : Chemistry of cofactors/coenzymes (Contd.)
- Lecture 40 : Chemistry of cofactors/coenzymes (Contd.)
- Lecture-41: Introduction to Drug Discovery Process
- Lecture-42: Fundamental Principles of Drug Development Process
- Lecture-43: Combinatorial chemistry
- Lecture-44: Neurotransmitters
- Lecture-45: Catechol amine based and GABA neurotransmitters
- Lecture-46: Hypertension: humoral mechanism and renin/angiotensin system
- Lecture-47: Inhibitor design of angiotensin converting enzyme
- Lecture 48: Antimicrobial drugs
- Lecture 49: Chemistry of penicillins
- Lecture 50:Resistance to beta-lactam antibiotics
- Lecture 51: Mechanistic studies of beta-lactamase
- Lecture 52: Non beta-lactam antibiotics
- Lecture 53: Mechanistic enzymology of Isopenicillin N synthase
- Lecture 54 : Polyketide Biosynthesis
- Lecture 55 : Biosynthesis of macrolide polyketides and introduction to virus
- Lecture 56 : Anti-viral drugs
- Lecture 57 : Cancer and Chemotherapy
- Lecture 58 : Ant-cancer drugs (contd)
- Lecture 59 : Aromatase inhibition and Anti-ulcer drugs
- Lecture 60 : Cholesterol lowering agents
- Lecture 61 : Cholesterol Biosynthesis
- Lecture 62 : Pharmakinetics and pharmadynamics
- Lecture 63 : QSAR principles