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Course10210609762 lectures

RNA Biology

Prof. Rajesh Ramachandran · IISER Mohali

Start with lecture 1 At NPTEL

Lectures

week-01

  1. Introduction to RNA Biology and RNA World-The Beginning Video
  2. Introduction to RNA Biology and RNA World-Evidences Video
  3. Introduction to RNA Biology and RNA World-Origin of Monomers Video
  4. Introduction to RNA Biology and RNA World-Shift to DNA Video
  5. Introduction to RNA Biology and RNA World-RNA Self Replication Video
  6. Introduction to RNA Biology and RNA World-Origin of RNA Enzymes Video

week-02

  1. RNA as Enzymes: The Ribozymes Video
  2. RNA as Enzymes: Structure and Functions Video
  3. RNA as Enzymes: The Present and Future Video

week-03

  1. RNA Transcription: The Central Dogma Video
  2. RNA Transcription: Initial Steps Video
  3. RNA Transcription: Different Stages Video
  4. RNA Transcription: Termination and RNA Modification Video
  5. RNA Transcription: Different Polymerases Video

week-04

  1. RNA Processing and Life Cycle: RNA Maturation and RNPs Video
  2. RNA Processing and Life Cycle: RNA Splicing Video
  3. RNA Processing and Life Cycle: Post Transcriptional Processing Video

week-05

  1. Alternative RNA Processing and Editing: Alternative Splicing Video
  2. Alternative RNA Processing and Editing: Implications of Introns Video
  3. Alternative RNA Processing and Editing: Splicing and Pathology Video
  4. Alternative RNA Processing and Editing: RNA Editing in Detail Video
  5. Alternative RNA Processing and Editing: Relevance of RNA Editing Video
  6. Alternative RNA Processing and Editing: Relevance in Immunology Video

week-06

  1. RNA Splicing, Export and Stability: Relevance of Introns Video
  2. RNA Splicing, Export and Stability: Introns in RNA Splicing Video
  3. RNA Splicing, Export and Stability: Different Spliceosomes Video
  4. RNA Splicing, Export and Stability: SMN Complex Video

week-07

  1. snRNA, rRNA, miRNA, siRNA Processing, Export and Function: Introns and Link to Splicing Video
  2. snRNA, rRNA, miRNA, siRNA Processing, Export and Function: RNA Helicases Video
  3. snRNA, rRNA, miRNA, siRNA Processing, Export and Function: Nucleo Cytoplasmic Transport Video
  4. snRNA, rRNA, miRNA, siRNA Processing, Export and Function: Nucleoporins and miRNAs Video
  5. snRNA, rRNA, miRNA, siRNA Processing, Export and Function: RNA Export Mechanisms Video
  6. snRNA, rRNA, miRNA, siRNA Processing, Export and Function: RNA Quality Control Video

week-08

  1. Mechanisms of RNA Decay and Non Coding RNAs: Decay Pathways Video
  2. Mechanisms of RNA Decay and Non Coding RNAs: The Exosomes Video
  3. Mechanisms of RNA Decay and Non Coding RNAs: mRNA Surveillance Video
  4. Mechanisms of RNA Decay and Non Coding RNAs: Mechanisms of RNA Decay Video
  5. Mechanisms of RNA Decay and Non Coding RNAs: Autoregulation of RNAs Video
  6. Mechanisms of RNA Decay and Non Coding RNAs: Introduction to Non-Coding RNAs Video

week-09

  1. Dosage Compensation and X-Inactivation: SRP and Different Modes of Compensation Video
  2. Dosage Compensation and X-Inactivation: Dosage Compensation of X Video
  3. Dosage Compensation and X-Inactivation: Omprinted vs Random X Inactivation Video
  4. Dosage Compensation and X-Inactivation: Molecular Basis of X-Inactivation Video
  5. Dosage Compensation and X-Inactivation: ES Cells and X-Inactivation Video

week-10

  1. Dosage Compensation, Xist and ncRNA in Imprinting: The Roles of YY1 Video
  2. Dosage Compensation, Xist and ncRNA in Imprinting: shRNAs and Gene Expression Video
  3. Dosage Compensation, Xist and ncRNA in Imprinting: Mechanism of RNAi in Action Video
  4. Dosage Compensation, Xist and ncRNA in Imprinting: Genomic Imprinting in Action Video
  5. Dosage Compensation, Xist and ncRNA in Imprinting: Different ncRNAs and their Roles Video
  6. Dosage Compensation, Xist and ncRNA in Imprinting: lncRNA-Induced Cancer Video
  7. Dosage Compensation, Xist and ncRNA in Imprinting: Xist and Cancer Video

week-11

  1. Telomere, Telomerase and Impact on Genomes: The Importance of Telomeres Video
  2. Telomere, Telomerase and Impact on Genomes: Telomerase and Aging Video
  3. Telomere, Telomerase and Impact on Genomes: Telomere Length as Marker of Aging Video
  4. Telomere, Telomerase and Impact on Genomes: Telomeres and Cancer Video
  5. Telomere, Telomerase and Impact on Genomes: Cell Cycle Arrest Video
  6. Telomere, Telomerase and Impact on Genomes: Maintenance and Manipulation of Telomeres Video

week-12

  1. Epitranscriptome and Protein Synthesis: Important RNA Modifications Video
  2. Epitranscriptome and Protein Synthesis: Readers, Writes and Erasers Video
  3. Epitranscriptome and Protein Synthesis: Biological Implications of RNA Modifications Video
  4. Epitranscriptome and Protein Synthesis: Roles of RNAs in Translation Video
  5. Epitranscriptome and Protein Synthesis: Mechanism of Translation Video

Syllabus and materials

At NPTEL, as the course publishes them.

Credits and licence

Institution
IISER Mohali
Department
Biotechnology
Teacher
Prof. Rajesh Ramachandran
Level
Undergraduate
Language
English
Subjects
Biology
Source
NPTEL
Licence
CC BY-NC-SA, as NPTEL states it. Non-commercial use only. NPTEL's terms
Attribution
NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge. Coordinated by IIT Madras.
Who can watch
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