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Course10410109220 lectures

Metal Mediated Synthesis - I

Prof. D. Maiti · IIT Bombay

Start with lecture 1 At NPTEL

About

The course covers an advance level of organometallic chemistry. Recent development of cross coupling reactions and their applications in organic synthesis, starting from small molecule to naturally and pharmaceutically important compounds, has been described in the prescribed course. In this course, a brief overview about the carbine chemistry and oxidative cyclization is also portrayed.

Intended audience: Students, PhD scholars, teachers, industry.

Prerequisites: Advance Organic and Inorganic Chemistry.

Lectures

Week 1

  1. Lecture 1 : Assymetric Hydrogenation YouTube
  2. Lecture 2 : Transition Metal Carbenes Fischerand Schrock Carbenes YouTube
  3. Lecture 3 : Olefin Metathesis YouTube
  4. Lecture 4 : Alkyne Metathesis YouTube
  5. Lecture 5 : Cyclopropanation Reaction YouTube

Week 2

  1. Lecture 6 : Catalytic Cyclopropanation Reaction and Introduction to Cross Coupling Reaction YouTube
  2. Lecture 7 : Kumada Coupling Reaction YouTube
  3. Lecture 8 : Suzuki Coupling Reaction YouTube
  4. Lecture 9 : Stille Coupling Reaction YouTube
  5. Lecture 10 : Assymetric Suzuki Coupling Reaction YouTube

Week 3

  1. Lecture 11 : Sonogashira Coupling Reaction YouTube
  2. Lecture 12 : Heck Coupling Reaction YouTube
  3. Lecture 13 : Assymetric Heck Reaction Introduction to Buchwald-Hartwig Coupling Reaction YouTube
  4. Lecture 14 : Buchwald-Hartwig Coupling Reaction YouTube
  5. Lecture 15 : Role of Ligands its Influence in Buchwald-Hartwig Coupling Reaction YouTube

Week 4

  1. Lecture 16 : Oxidative Cyclization Process YouTube
  2. Lecture 17 : Application of Oxidative Cyclization in Natural Product Synthesis YouTube
  3. Lecture 18 : Synthesis of Reactive Metallacycle Intermediate Via-Beta-Abstraction and their Applications YouTube
  4. Lecture 19 : Kulinkovich Reaction and its Mechanism YouTube
  5. Lecture 20 : Pauson–Khand Reaction YouTube

Syllabus and materials

At NPTEL, as the course publishes them.

Credits and licence

Institution
IIT Bombay
Department
Chemistry and Biochemistry
Teacher
Prof. D. Maiti
Level
Undergraduate
Language
English
Subjects
Chemistry
Source
NPTEL
Licence
CC BY-NC-SA, as NPTEL states it. Non-commercial use only. NPTEL's terms
Attribution
NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge.
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