Lecture 3 of 62Week 1
Regeneration: In Normal Life and Implications
Prof. Rajesh Ramachandran · IISER Mohali
Credits and licence
- From
- Regeneration Biology, IISER Mohali (at NPTEL)
- Licence
- CC BY-NC-SA, as NPTEL states it. Non-commercial use only.
- Attribution
- NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge. Coordinated by IIT Madras.
- Who can watch
- Teens profiles and older. How courses are placed
All the lectures
- Basics of Regeneration: Basics and Types
- Regeneration, Wound Healing and Scar Formation in Different Regenerative Capacity
- Regeneration: In Normal Life and Implications
- Tissue Regeneration: Mammalian Context
- Liver Regeneration: Signaling Events
- Liver Regeneration: Mechanistic Insights
- Regeneration: lessons from animal model Hydra
- Mechanisms of regeneration in Hydra
- Asexual Reproduction- Fragmentation. Morphallaxis, Epimorphosis, lessons from Hydra
- Mechanisms of regeneration in Planaria
- Planaria regeneration-polarity and gradient in regeneration
- Planaria regeneration: Neoblasts and organ formation & Species type and environment.
- Position control genes and regeneration-Part A
- Position control genes and regeneration-Part B
- Progenitor targeting and ectopic organs
- Tissue dedifferentiation, cellular reprograming into blastema Cellular types in regeneration. Neural crest cells in vertebrates
- Totipotency, pluripotency, multipotency and unipotency, in regeneration context
- Adult stem cells: Natural and induced and their roles in regeneration-zebrafish
- Common cellular events during regeneration, embryonic development, and cancer
- Epithelial to mesenchymal transition (EMT) and mesenchymal to epithelial transition (MET) in regeneration
- Organ regeneration: Basics with examples
- Zebrafish fin regeneration-in a brief
- Zebrafish heart regeneration-in a brief
- Zebrafish retina regeneration-in a brief
- Spinal cord and brain regeneration-Conclusive mechanisms of regeneration
- Cellular, Molecular and Genetic factors involved in retina regeneration
- Detailed mechanisms of fin regeneration
- Retina regeneration-importance of Shh signaling Roles of epigenetic factors and their involvement in regeneration
- Importance of regeneration associated gene induction events-Transcription activators and repressors
- Roles of different cellular signaling in regeneration: Examples- Wnt signaling
- Different cellular signaling during regeneration-Overview
- Different cellular signaling during regeneration. Examples- Jak-STAT and Fgf signaling
- Different cellular signaling during regeneration -Egf, and Hippo signaling
- Roles of Delta-Notch signaling during regeneration
- Tgf-beta signaling during regeneration
- Organ regeneration: An overview
- Accessory limb model of regeneration: lessons from Axolotl and newt
- Nerve-dependent regeneration-Axolotl and Newt
- Roles of Histone deacetylases in regeneration of vertebrates like fishes and amphibians
- Dynamics of immune system in organ regeneration
- Extracellular matrix and its roles in tissue regeneration
- Induced pluripotency and roles of iPFs during tissue Hox genes and homeotic transformation
- Animal cloning: implications in regeneration
- Embryonic stem cells, cord blood stem cells and adult stem cells
- Ethics of stem cell research in regeneration studies, regenerative medicine and biotechnology
- Tissue engineering-Why and how?
- History of tissue engineering
- Different steps in tissue engineering
- Different aspects of organ culture
- Major challenges in tissue engineering in practice
- Tissue 3D printing and organ culture
- Importance of scaffolds in tissue engineering
- Stem cells for tissue engineering-Use of CRISPR-Cas9 for genome targeting
- Types of adult stem cells and trans-differentiation for tissue engineering
- Influence of niches and scaffolds on stem cells: An organ culture perspective
- The basics of regeneration put into practice in vitro.
- Adhesion, migration and aggregation of stem cells
- Artificial, liver, kidney and urinary bladder for transplantation in patients
- Limbal stem cells and artificial cornea
- Xenotransplantation vs organ culture in practice
- Future implications of regeneration in mammals
- Future implications of Organ culture in patient care