Course10210606569 lectures
BioInformatics: Algorithms and Applications
Prof. Michael Gromiha · IIT Madras
Lectures
Week 1
- Concepts and importance of Bioinformatics
- Complexities in biological systems
- DNA sequence analysis
- Sequence based parameters
- Database
- Database categories
Week 2
- Protein structure and function
- Protein structure and function II
- Protein sequence databases
- Protein sequence databases II
- Pairwise alignment
- Pairwise alignment II
- Uniprot Demo
Week 3
- Sequence alignment
- Sequence alignment II
- Sequence alignment: Online resources
- Sequence alignment: Online resources II
- Conservation score
- Conservation score II
- Blast Demo
Week 4
- Phylogenetic trees
- Phylogenetic trees II
- Protein sequence analysis
- Protein sequence analysis II
- Hydrophobicity profiles
- Patterns and PSSM profiles
Week 5
- Construction of Non-redundant datasets I
- Non-redundant datasets II
- Protein secondary structure
- Secondary structure prediction I
- Secondary structure prediction II
- Secondary structure prediction III
Week 6
- Protein tertiary structure I
- Protein tertiary structure II
- Protein structure analysis - I
- Protein structure analysis II
- Protein structure analysis III
- Demo: PDB or Pymol or PDBParam
Week 7
- Protein structure analysis - IV
- Protein structure prediction - I
- Protein structure prediction - II
- Protein stability - I
- Protein stability - II
- Demo: Homology Modelling
Week 8
- Stabilizing residues
- Thermodynamic database
- Stability of proteins upon mutations
- Stability of proteins upon mutations II
- Demo: ProTherm
Week 9
- Protein folding rate I
- Protein folding rate II
- Protein interactions I
- Protein interactions II
- Computer aided drug design I
Week 10
Week 11
- Demo: Autodock
- awk programming - I
- awk programming - II
- Development of algorithms - I
- Development of algorithms - II
Week 12
Syllabus and materials
At NPTEL, as the course publishes them.
Credits and licence
- Institution
- IIT Madras
- Department
- Biotechnology
- Teacher
- Prof. Michael Gromiha
- Level
- Undergraduate
- Language
- English
- Subjects
- Biology
- Source
- NPTEL
- Licence
- CC BY-NC-SA, as NPTEL states it. Non-commercial use only. NPTEL's terms
- Attribution
- NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge.
- Who can watch
- NPTEL gives no rating. Invisible Network shows it to Teens profiles and older, judged from what the source says about it. How courses are placed
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