Toxicology MSDT

by Toxicology MSDT

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One of the challenges of recruiting undergraduates into the toxicology graduate research programs is a lack toxicology training programs and courses at the undergraduate level. Course content developed through this program are accessible to the general public. The intent is to provide content where other undergraduate students, K-12 educators, and the interested public encounter content providing an introduction to the discipline of toxicology.

Description from LibreTexts.

Subjects
Chemistry, Environmental Chemistry
Licence
CC BY-NC 4.0, as LibreTexts states it. Non-commercial use only.
Who can read
Tweens profiles and older, judged from its title and subjects

Contents

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  1. Front Matter
  2. TitlePage
  3. InfoPage
  4. Table of Contents
  5. Licensing
  6. Preface
  7. 1: Pathophysiology
  8. 1.1: What is Pathophysiology?
  9. 1.3: Outcomes of Targeted and Non-Targeted Toxicity
  10. 1.4: Cellular Response to Toxicant-Induced Injury
  11. 1.5: Repair & Adaptation
  12. 1.6: Patterns of Toxic Injury​
  13. Final Evaluation
  14. 2: Biochemistry and Molecular Genetics
  15. 2.1: Introduction to Biomolecules and Cell Components
  16. 2.2: Cell Structure and Subcellular Compartments
  17. 2.3: DNA and RNA Metabolism
  18. 2.4: Epigenetic Mechanisms
  19. Section 2 Final Evaluation
  20. 3: Principles of Genetic Toxicology
  21. 3.1: Introduction to Genetic-toxicology Assay
  22. 3.2: Different Genetic Damages or Mutations
  23. 3.3: Different Genetic-Toxicology Assays
  24. 3.4: Different Cytotoxicity Assays
  25. 3.5: Epigenetics Assay
  26. Section 3 Final Evaluation
  27. 4: Applied Systems Toxicology
  28. 4.1: Systems Toxicology​
  29. 4.2: Dose Level and Applied Toxicology​
  30. 4.3: Tools and Technologies in Systems Toxicology​
  31. 4.4: Other Approaches for Predictive Toxicity Modeling
  32. 4.5: Technologies Used In Systems Biology/Toxicology​
  33. 4.6: Takeaways ​Summary
  34. Section 4 Final Evaluation
  35. 5: Regulatory Toxicology
  36. 5.1: Introduction to Regulatory Toxicology
  37. 5.2: Global Regulatory Toxicology​​
  38. 5.3: Topic 3: Regional Regulatory Toxicology
  39. 5.4: National Regulatory Toxicology
  40. 5.5: State Regulatory Toxicology​
  41. 5.6: Non-Governmental Regulatory Toxicology
  42. Section 5 Final Evaluation
  43. 6: Principles of Toxicology
  44. Section 1: Introduction to Toxicology
  45. 1.1: What is toxicology?
  46. 1.2: Basic Terminology
  47. Section 2: Dose and Dose Response
  48. 2.1: Dose and It's Impact on Toxicity
  49. 2.2: The Dose Response Relationship
  50. 2.3: Dose Estimates of Toxic Effects
  51. 2.4: Determining the Safety of a Drug
  52. 2.5: NOAEL and LOAEL
  53. Section 3: Toxic Effects
  54. 3.1: Types of Toxic Effects
  55. 3.2: Factors Affecting Toxicity
  56. 3.3: Systemic Toxic Effects
  57. 3.4: Organ Specific Toxic Effects
  58. Section 4: Interactions
  59. 4.1: Interactions
  60. Section 5: Toxicity Testing Methods
  61. 5.1: Testing and Assessing Toxicity
  62. 5.2: Clinical Investigations and Other Types of Human Data
  63. 5.3: Epidemiology Studies
  64. Section 6: Risk Assessment
  65. 6.1: Risk Assessment
  66. 6.2: Hazard Identification
  67. 6.3: Dose-Response Assessment
  68. 6.4: Exposure Assessment
  69. 6.5: Risk Characterization
  70. Section 7: Exposure Standards and Guidelines
  71. 7.1: Exposure Standards and Guidelines
  72. 7.2: Regulation of Consumer Products and Drug Safety
  73. 7.3: Environmental Exposure Standards/Guidelines
  74. 7.4: Occupational (Workplace) Exposure Standards/Guidelines/Approaches
  75. Section 8: Basic Physiology
  76. 8.1: Introduction to Basic Physiology
  77. 8.2: Homeostasis
  78. 8.3: Organs and Organ Systems
  79. 8.4: Tissues
  80. 8.5: Cells
  81. 8.6: Chemicals
  82. Section 9: Introduction to Toxicokinetics
  83. 9.1: What is Toxicokinetics
  84. Section 10: Absorption
  85. 10.1: Introduction to Absorption
  86. 10.2: Gastrointestinal Tract
  87. 10.3: Respiratory Tract
  88. 10.4: Dermal Route
  89. 10.5: Other Routes of Exposure
  90. Section 11: Distribution
  91. 11.1: Introduction to Distribution
  92. 11.2: Influence of Route of Exposure
  93. 11.3: Disposition Models
  94. 11.4: Structural Barriers to Distribution
  95. 11.5: Storage Sites
  96. Section 12: Biotransformation
  97. 12.1: Introduction to Biotransformation
  98. 12.2: Chemical Reactions
  99. 12.3: Biotransformation Sites
  100. 12.4: Modifiers of Biotransformation
  101. Section 13: Excretion
  102. 13.1: Introduction to Secretion
  103. 13.2: Urinary Excretion
  104. 13.3: Fecal Excretion
  105. 13.4: Exhaled Air
  106. 13.5: Other Routes
  107. Section 14: Cellular Toxicology
  108. 14.1: Adaptation
  109. 14.2: Cell Damage and Tissue Repair
  110. 14.3: Cancer
  111. 14.4: Neurotoxicity
  112. Section 15: Intuitive Toxicology and Risk Communication
  113. 15.1: Intuitive Toxicology
  114. 15.2: Risk Communication
  115. Section 16: Environmental Toxicology, Environmental Health, and One Health
  116. 16.1: Environmental Toxicology
  117. 16.2: Environmental Health
  118. 16.3: One Health
  119. Section 17: Conclusion
  120. Back Matter
  121. Index
  122. Glossary
  123. Detailed Licensing