16.4: Immediate Hypersensitivities - Type V

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    Describe the mechanism for Type V (Stimulatory) hypersensitivity and give an example.

    Type V (Stimulatory Hypersensitivity) invovles making Antibodies are made against a particular hormone receptor on a hormone-producing cell. This leads to the overstimulation of those hormone-producing cells. An example is Graves' disease where antibodies are made against thyroid-stimulating hormone receptors of thyroid cells. The binding of the antibodies to the TSH receptors results in constant stimulation of the thyroid leading to hyperthyroidism.

    Summary

    1. During type V (stimulatory hypersensitivity) antibodies are made against a particular hormone receptor of a hormone-producing cell leading to the overstimulation of those hormone-producing cells.
    2. An example is Graves' disease where antibodies are made against thyroid-stimulating hormone receptors of thyroid cells.

    Questions

    Study the material in this section and then write out the answers to these questions. Do not just click on the answers and write them out. This will not test your understanding of this tutorial.

    1. Describe the mechanism for Type V (Stimulatory) hypersensitivity and give an example. (ans)

    This page titled 16.4: Immediate Hypersensitivities - Type V was last modified on Thu, 31 Aug 2023 18:54:58 GMT and is shared under a CC BY 4.0 license and was authored, remixed, and/or curated by Gary Kaiser via source content that was edited to the style and standards of the LibreTexts platform.