Short20161 min854×480

Stereotypic-wheel-running-decreases-cortical-activity-in-mice-ncomms13138-s6

Fisher S, Cui N, McKillop L, Gemignani J, Bannerman D, Oliver P, Peirson S, Vyazovskiy V

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Supplementary Movie 5 LFP and MUA in an awake mouse during voluntary wheel running. Top: Raw electroencephalogram (EEG) signals recorded from the frontal (yellow) and occipital (red) cortex together with neck muscle electromyogram (EMG). Middle: Raw traces of local field potentials (LFP) and corresponding multiunit activity (MUA) in the same seven channels recorded from the somatosensory cortex in a representative freely behaving mouse during a period of running wheel activity. Bottom bar plot corresponds to running wheel activity (each vertical bar represents a single count of the wheel rung). Note the occurrence of brief isolated periods of reduced MUA that coincide with positive LFP waves during high speed running. The first six examples are highlighted with arrows. The screen width corresponds to a 5-second period, and yellow numbered tick marks at the top represent 1 second segments.

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Fisher S, Cui N, McKillop L, Gemignani J, Bannerman D, Oliver P, Peirson S, Vyazovskiy V
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