Podcasts · Technology · Business

The a16z Show

Andreessen Horowitz

300 episodes

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

Episodes page 1 of 6

  1. Reinventing School for the AI Era | Joe Liemandt, Gagan Biyani & Erik Torenberg

    · 57 min · Episode 1241

    What should school look like if AI can help students learn dramatically faster? Alpha School founder Joe Liemandt argues the answer isn’t to fill the extra time with more academics, but to redesign school around the…

  2. OpenAI: When AI Agents Use Computers Faster Than You

    · 45 min · Episode 1240

    AI agents are approaching a point where they can use computers faster than expert humans, turning the user interface itself into a universal way for AI to interact with software. OpenAI’s Ari Weinstein and James Sun…

  3. The New Startup Playbook | Box CEO Aaron Levie

    · 34 min · Episode 1239

    Can a 10-person startup outperform a company with hundreds of employees? Box CEO Aaron Levie argues AI agents are giving small teams a level of leverage that simply wasn't economically possible before, creating a…

  4. What It Takes to Win as a Founder | Ben Horowitz

    · 42 min · Episode 1238

    What does it take to build a company when AI is changing the rules this quickly? Ben Horowitz argues that technology may make companies easier to start, but the hardest parts of entrepreneurship, making decisions under…

  5. Amazon CEO Andy Jassy on the $220 Billion AI Buildout

    · 1 h 01 min · Episode 1236

    Amazon expects to spend roughly $220 billion in CapEx in 2026, yet CEO Andy Jassy says the company is still leaving meaningful AI demand on the table.** He believes the buildout could ultimately help make AWS a $1…

  6. The Frontier Ideas a16z Wants to Fund | Marc Andreessen, Ben Horowitz & Chris Dixon

    · 1 h 01 min · Episode 1237

    a16z is expanding a16z crypto into a16z Frontier, a broader mandate to back founders building at the edges of what's possible. Chris Dixon joins Marc Andreessen, Ben Horowitz, and Erik Torenberg to explain why founders…

  7. The Missing Infrastructure for AI Agents: Documents | Reducto’s Adit Abraham

    · 38 min · Episode 1235

    AI agents can reason over enormous amounts of information, but much of the world’s actual work is still trapped in PDFs, spreadsheets, scans, and other formats that models struggle to reliably understand. Reducto…

  8. What Happens When Everyone Has a Health Expert in Their Pocket? | OpenAI’s Karan Singhal

    · 56 min · Episode 1234

    More than 300 million people use ChatGPT for health and wellness questions each week. OpenAI’s Karan Singhal thinks that’s only the beginning: the longer-term goal is AI that can help people navigate their health…

  9. What Happens When Al Agents Can Spend Your Money?

    · 1 h 03 min · Episode 1233

    Why hasn't AI transformed everyday work as quickly as coding? Town CEO Jean-Denis Greze argues the bottleneck isn't intelligence, but making AI useful to people who don't have the time or technical skills to build…

  10. Why Real-World AI Is Harder Than the Benchmark | EliseAI’s Mario Martone

    · 24 min · Episode 1232

    What changes when an AI mistake doesn’t just hurt a benchmark score, but affects someone’s housing or healthcare? EliseAI Head of Applied Research Mario Martone argues that deploying AI in essential industries requires…

  11. Why AI Could Finally Fix Healthcare Access | Zocdoc CEO Oliver Kharraz

    · 35 min · Episode 1231

    Why is booking a doctor's appointment still so difficult, and can AI finally change that? Zocdoc CEO Oliver Kharraz argues that the real problem isn't finding doctors, but connecting patients to accurate availability…

  12. AI Can Write the Code. Can It Run the System? | Grepr CEO Jad Naous

    · 1 h 00 min · Episode 1230

    a16z General Partner Martin Casado sits down with Grepr CEO Jad Naous to ask what comes after AI learns to write code: can it also debug and operate the systems that code creates? Jad shares how AI has transformed…

  13. When AI Agents Start Spending Your Money | Alex Rampell & Terry Angelos

    · 51 min · Episode 1229

    a16z General Partner Alex Rampell sits down with VGS Executive Board Member, Terry Angelos, to unpack what happens to payments when AI agents go from recommending what to buy to actually making the purchase. Terry…

  14. Can Open Models Keep Up With the AI Frontier? | Nathan Lambert

    · 1 h 00 min · Episode 1228

    a16z Partner Lisha Li sits down with AI researcher and Trillium founder Nathan Lambert to ask how durable the gap really is between frontier AI labs and open models. Nathan argues that OpenAI and Anthropic have…

  15. Can AI Break Cryptography? What the Experts Actually Think

    · 42 min · Episode 1227

    Could AI break the cryptography protecting everything from crypto wallets and banking to private messages? Recent advances in AI-driven mathematical research have sparked new warnings about the security of today's…

  16. The Race to Recursive Self-Improving AI

    · 33 min · Episode 1226

    a16z General Partner Martin Casado sits down with MakerMaker.AI co-founders Dhaval Adjodah and Owen He to unpack recursive self-improvement, or RSI, and separate the increasingly popular term from what it would…

  17. Nick Bostrom: How Should We Navigate Superintelligence?

    · 54 min · Episode 1225

    Nick Bostrom joins Theo Jaffee and Sofia Puccini on MTS to revisit the ideas about superintelligence and existential risk that he helped bring into the mainstream, now that increasingly capable AI systems actually…

  18. What Makes a Great Entrepreneur? | Ben Horowitz on Vintage x Vintage

    · 52 min · Episode 1224

    a16z co-founder and General Partner Ben Horowitz joins James Norman on the inaugural episode of Vintage x Vintage for a conversation spanning entrepreneurship, investing, hip-hop, and what changes when AI makes…

  19. Chips, Memory, and Power | Pat Gelsinger

    · 54 min · Episode 1223

    a16z's Raghu Raghuram and Guido Appenzeller sit down with Playground Global General Partner and former Intel CEO Pat Gelsinger to discuss the next wave of semiconductor innovation and the physical constraints shaping…

  20. Building the Cloud for an Agentic World | AWS CEO Matt Garman

    · 56 min · Episode 1222

    a16z’s Raghu Raghuram sits down with AWS CEO Matt Garman to discuss how AI is reshaping the cloud, from the needs of AI-native startups to infrastructure increasingly designed for agents. Matt explains how AWS is…

  21. How Valon Rebuilt a $13 Trillion Industry From Scratch

    · 41 min · Episode 1221

    a16z General Partner Angela Strange sits down with Valon’s Andrew Wang and Linda Du to unpack what it takes to rebuild the infrastructure underneath a $13 trillion mortgage market that still relies heavily on systems…

  22. Building Defense for the Agentic Era: Kevin Mandia

    · 49 min · Episode 1220

    a16z General Partner David George sits down with Armadin founder and CEO Kevin Mandia to discuss what happens to cybersecurity when attackers can operate at machine speed. After 30 years in security and building…

  23. The Top 100 Consumer AI Apps: Who’s Actually Paying?

    · 51 min · Episode 1219

    a16z Editorial Partner Elena Burger sits down with investing partners Olivia Moore and Josh Elman to unpack the seventh edition of a16z’s Top 100 Consumer AI Apps, including a new dimension this time: what consumers…

  24. David George & Jack Altman on AI, Autonomy, and the Next $25 Trillion

    · 55 min · Episode 1218

    a16z General Partner David George joins Jack Altman on Uncapped to make the case that many of the biggest debates in AI are framed the wrong way. Frontier models or open source? Labs or applications? David’s answer is…

  25. Beyond the God Model | Alex Atallah & Amjad Masad

    · 48 min · Episode 1217

    A16z’s Erik Torenberg sits down with OpenRouter’s Alex Atallah and Replit founder and CEO Amjad Masad to discuss why the future of AI may look less like one all-purpose model and more like an ecosystem of specialized…

  26. Why AI Agents Can Beat the Incumbents

    · 1 h 00 min · Episode 1216

    a16z’s Seema Amble and Elena Burger sit down with Lio co-founder and CEO Vladimir Keil to ask where AI-native startups have an advantage when incumbent software companies already own the customer, the data, and the…

  27. Rebuilding the Internet for Privacy | Barrett Lyon on DoxxNet

    · 45 min · Episode 1215

    a16z’s Joel de la Garza sits down with DoxxNet founder Barrett Lyon to discuss what it would take to rebuild the internet around privacy, direct communication, and less dependence on centralized intermediaries.…

  28. The $1 Trillion AI Buildout | State of Markets

    · 54 min · Episode 1214

    a16z’s David George, Sarah Wang, Alex Immerman, and Santiago Rodriguez unpack 25 key charts from the latest State of Markets presentation, from the scale of the AI infrastructure buildout to what adoption looks like…

  29. The Personal Agent Race Is Here | Anish Acharya & David Pawlan

    · 51 min · Episode 1213

    a16z General Partner Anish Acharya sits down with Assistant Benchmark creator David Pawlan to unpack the sudden explosion of personal AI agents and what it will take for one to become part of everyday life. David has…

  30. AI Can Write Code. Why Isn’t Software Better?

    · 43 min · Episode 1212

    a16z’s Ben Horowitz and Martin Casado sit down with TypeSafe AI founder Diogo Almeida to ask a simple question: AI has become remarkably capable, so where is all the automation? Diogo argues that coding agents may…

  31. Building a Team at AI Speed | Harvey’s Maggie Landers

    · 48 min · Episode 1211

    a16z’s Katie Kirsch sits down with Harvey VP of Talent Maggie Landers to discuss what happens inside a company growing at AI speed, and how you preserve culture while adding more than 1,000 employees in a year. Maggie…

  32. Aaron Levie, Steven Sinofsky & Martin Casado: How Do You Secure a World of AI Agents?

    · 56 min · Episode 1210

    Erik Torenberg sits down with Box CEO Aaron Levie, and a16z’s Martin Casado, and Steven Sinofsky to debate how the AI industry should think about safety, security, and regulation as increasingly capable agents move…

  33. The Reputation Graph of Silicon Valley | Introducing Cosign

    · 50 min · Episode 1208

    a16z’s Erik Torenberg sits down with Josh Elman, Olivia Moore, and David Booth to introduce Cosign, a new product built around professional reputation and the people, companies, and products you’re willing to put your…

  34. The Case Against an AI Pause | Eddy Lazzarin

    · 28 min · Episode 1209

    a16z crypto General Partner Eddy Lazzarin joins Theo Jaffee on MTS to debate the increasingly prominent calls to slow AI development and whether the current safety conversation is conflating very different kinds of…

  35. Amjad Masad on Rethinking College for the AI Era

    · 48 min · Episode 1207

    Erik Torenberg sits down with Replit founder and CEO Amjad Masad and Horowitz and Andreessen Academy co-founder and CEO Gagan Biyani to ask what education should look like for a generation growing up with AI. Amjad…

  36. Why a16z is Building a New School for the AI Era | Ben Horowitz

    · 43 min · Episode 1206

    Ben Horowitz and Erik Torenberg sit down with Gagan Biyani to introduce the Horowitz and Andreessen Academy and discuss a bigger question: what should education look like when AI is rapidly changing the skills people…

  37. AI Safety Language Is Destroying the Debate | Steven Sinofsky

    · 29 min · Episode 1205

    a16z Board Partner and former Microsoft Windows president Steven Sinofsky joins Theo Jaffee and Sofia Puccini on MTS to argue that the language we use to describe AI failures is making it harder to understand what’s…

  38. Nas, Grandmaster Caz, Steve Stoute & Ben Horowitz on Paying Hip-Hop’s Pioneers Their Due

    · 57 min · Episode 1204

    Ben Horowitz and Erik Torenberg sit down with Nas, Grandmaster Caz, and Steve Stoute for a conversation about the Paid in Full Foundation and its mission to recognize and support the pioneers who built hip-hop. Ben,…

  39. What Makes a Consumer AI Product Stick? | Josh Elman

    · 1 h 00 min · Episode 1203

    a16z Partner Josh Elman joins Ollie Forsyth on New Economies to discuss the next wave of consumer AI and what separates a product people try once from one that becomes part of their everyday lives. Josh argues that…

  40. Databricks CEO on AI Pacing, Cyber Risk, and the Enterprise

    · 1 h 09 min · Episode 1202

    Databricks co-founder and CEO Ali Ghodsi joins a16z General Partners Martin Casado and Sarah Wang for a conversation about AI risk, recursive self-improvement, cybersecurity, and what’s actually holding back enterprise…

  41. The Next Frontier of AI Video Is Control

    · 40 min · Episode 1201

    a16z General Partner Jennifer Li sits down with fal co-founder Gorkem Yurtseven and Head of Engineering Batuhan Taskaya to discuss what changes when generative video becomes fast enough to run in real time. They…

  42. The AI-Native CRM

    · 53 min · Episode 1200

    a16z’s Alex Rampell and Joe Schmidt sit down with Lightfield co-founder and CEO Keith Peiris to discuss what it takes to rethink the CRM for an AI-native world, and the unusual pivot that got him there. Keith…

  43. The Age of Body Futurism | Ruby Justice Thelot

    · 43 min · Episode 1199

    Elena Burger sits down with academic and cyber ethnographer Ruby Justice Thelot to explore the increasingly blurry line between internet culture and the real world, and how to tell the difference between a trend that’s…

  44. Greg Brockman on Why OpenAI Says We’re Entering the AGI Era

    · 51 min · Episode 1198

    Ben Horowitz and Erik Torenberg sit down with OpenAI co-founder and President Greg Brockman to discuss why he believes AI has entered a new phase, what OpenAI’s latest models reveal about the path to AGI, and the…

  45. World Models, Robotics, and the Future of 3D AI

    · 24 min · Episode 1197

    World Labs co-founder Justin Johnson joins MTS hosts Theo Jaffee and Sofia Puccini to discuss Atlas, World Labs’ latest world model, and the broader case for AI systems that understand and interact with the physical…

  46. Why Companies Are Becoming a Series of Loops | Anish Acharya on Lenny’s Podcast

    · 1 h 18 min · Episode 1196

    a16z General Partner Anish Acharya joins Lenny Rachitsky on Lenny’s Podcast to discuss why fears of an AI-driven “permanent underclass” may be misplaced, how AI is changing the way companies operate, and why the…

  47. What It Takes to Build a Startup | Andrew Chen & Matt Perault

    · 38 min · Episode 1195

    a16z’s Matt Perault sits down with General Partner and Speedrun lead Andrew Chen on the a16z AI Policy Brief to explore what “Little Tech” actually looks like at the earliest stages, and why the realities of building a…

  48. How AI Is Rewriting the Power Law of Venture Capital

    · 49 min · Episode 1194

    a16z’s Jen Kha and David George sit down with Accolade Partners’ Aram Verdiyan to discuss how AI is changing the power law of technology investing, why the largest companies can compound advantages in ways that weren’t…

  49. Who Grades the AI Models? | Ben Horowitz & Rayan Krishnan

    · 40 min · Episode 1193

    a16z’s Erik Torenberg, Ben Horowitz, and Jennifer Li sit down with Vals founder and CEO Rayan Krishnan to discuss one of AI’s increasingly difficult problems: how do you actually measure whether a model is getting…

  50. OpenAI Researchers on the Future of Mathematical Reasoning

    · 1 h 05 min · Episode 1192

    a16z Infra Partner Lisha Li sits down with OpenAI mathematicians Mehtaab Sawhney and Mark Sellke to discuss how quickly AI’s mathematical capabilities are advancing, what recent results reveal about model reasoning,…

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