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Diffuse Large B-Cell Lymphoma — An Interview with Dr L Elizabeth Budde on Employing CD20 x CD3 Bispecific Antibodies (Companion Faculty Lecture)

· 28 min

Episode Diffuse Large B-Cell Lymphoma — An Interview with Dr L Elizabeth Budde on Employing CD20 x CD3 Bispecific Antibodies (Companion Faculty Lecture)

0:00 27:35

Featuring a slide presentation and related discussion from Dr L Elizabeth Budde, including the following topics:

• Overview of approved and investigational CD20 x CD3 bispecific antibodies (BsAbs) in non-Hodgkin lymphoma; key findings from Phase II studies evaluating glofitamab and epcoritamab in relapsed/refractory (R/R) diffuse large B-cell lymphoma (0:00) • Bringing BsAbs into earlier-line settings; key findings from Phase III studies (7:49) • Key findings from the Phase III EPCORE DLBCL-1 and EPCORE DLBCL-4 studies and Phase II EPCORE NHL-1 study (14:12) • A Phase Ib/II study of glofitamab/polatuzumab in R/R large B-cell lymphoma; investigating the use of BsAbs as front-line therapy and as combination therapy (17:58) • Managing treatment-related adverse events; final takeaways (22:53)

CME information and select publications

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