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Prostate Cancer with PTEN Deficiency — An Interview with Dr Neeraj Agarwal (Companion Faculty Lecture)

· 24 min

Episode Prostate Cancer with PTEN Deficiency — An Interview with Dr Neeraj Agarwal (Companion Faculty Lecture)

0:00 23:44

Featuring a slide presentation and related discussion from Dr Neeraj Agarwal, including the following topics:

• Therapeutic targets of systemic therapy in prostate cancer (0:00) • Prevalence of genomic alterations in prostate cancer including PTEN deficiency; prognostic and predictive value (3:52) • Optimal timing of and approach to PTEN assessment; pathophysiology surrounding PTEN loss (9:29) • Comparison of ipatasertib and capivasertib; key findings from Phase III IPATential150 and CAPItello-281 studies (14:26) • Safety and tolerability profile of capivasertib; strategies for management of adverse events (19:21)

CME information and select publications

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