Podcasts · Technology

This Week in Startups

Jason Calacanis

300 episodes

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world's greatest founders, operators, investors, and innovators.

Episodes page 1 of 6

  1. Pregame Your Launch Before Your App Exists (w/ Amanda Bradford) | E2355

    · 57 min

    This Week In Startups is made possible by: Odoo: https://odoo.com/twist G2i: https://g2i.co/twist Rippling: https://rippling.ai/twist Plaud: https://plaud.ai/twist Today’s show: Amanda Bradford’s “launch party”…

  2. OpenAI’s $1.25T Raise, Starlink Mobile & Zuck’s Tax Deal | EP 2354

    · 1 h 33 min

    This Week In Startups is made possible by: Plaud - https://plaud.ai/twist Sentry - https://sentry.io/twist Lightfield - https://lightfield.app Rippling - https://rippling.ai/twist Today’s show: Is OpenAI finally…

  3. We asked 3 VCs: would you invest in Elizabeth Holmes’ next startup? | E2353

    · 1 h 41 min

    This Week In Startups is made possible by: DigitalOcean - Head to https://do.co/twist to start building on DigitalOcean's AI-Native Cloud today — and cut your AI workload costs by up to 50% Odoo: The all-in-one…

  4. Anthropic Gives Away 5% of Its Shares, Clone’s Muscle Robot, ElevenLabs Steals Podcaster's Voice

    · 1 h 34 min

    This Week In Startups is made possible by: Plaud: https://plaud.ai/twist Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Vanta: https://www.vanta.com/twist Rippling:…

  5. Flying Cars, OpenAI Spies, Why AI Isn’t Sticking (Superhuman CEO)

    · 1 h 33 min

    This Week In Startups is made possible by: Lightfield: https://lightfield.app Every.io: https://every.io/ PayPal: https://paypal.com/business Plaud: https://plaud.ai/twist GoDaddy: https://www.godaddy.com/…

  6. The Ex-DeepMind Researcher Taking On China’s Open Source AI

    · 1 h 00 min

    This Week In Startups is made possible by: Paper: https://getpaper.ai/twist Superhuman: https://superhuman.com/ Odoo: https://Odoo.com/twist Today’s show: Misha Laskin of Reflection AI joins Jason to explain why…

  7. The Gadget That's Better in Crowds Than Your Phone + Ring’s Founder Before Amazon Bought It | E2349

    · 1 h 20 min

    This Week In Startups is made possible by: Plaud: https://plaud.ai/twist Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain NetSuite: https://netsuite.ai/twist The Conservation Fund:…

  8. Jason Reacts To Japanese Founder Pitches + Fireside Chat With Yuki Shirato

    · 1 h 25 min

    This Week In Startups is made possible by: Lightfield: https://lightfield.app Rippling: https://Rippling.ai/twist Upwork: https://upwork.com Today’s show: AssetHub built an AI agent that recreates licensed…

  9. What VCs Really Think About Personal AI Agents | E2347

    · 1 h 19 min

    This Week In Startups is made possible by: Plaud: https://plaud.ai/twist Odoo: https://odoo.com/twist Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Quo:…

  10. Jason Mentors The Next Generation + Why AI Is Bad at Teaching (Aristotle Interview) | E2346

    · 1 h 11 min

    This Week In Startups is made possible by: Vanta: https://www.vanta.com/twist DigitalOcean: https://do.co/twist Sentry: https://sentry.io/twist Plaud: https://plaud.ai/twist Today’s show: The smarter AI gets, the…

  11. Inside The Startup Building Uncensored AI (Abliteration AI) | EP 2345

    · 53 min

    This Week In Startups is made possible by: Every.io: https://every.io/ Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Odoo: https://odoo.com/twist Plaud: https://plaud.ai/twist…

  12. Justin Kan & Brian Chesky: The Rejections That Built Twitch and Airbnb | E2344

    · 1 h 18 min

    This Week In Startups is made possible by: Plaud: https://plaud.ai/twist CLA: https://www.claconnect.com/withyou Sentry: https://sentry.io/twist Lightfield: https://lightfield.app Today’s show: Google once…

  13. Jason’s Put a $5K Bounty on His Dream Chrome Extension | E2338

    · 41 min

    This Week In Startups is made possible by: Every.io: https://every.io/ Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Sentry: https://sentry.io/twist Today’s show: A product that…

  14. The 5 Companies Apple Must Buy

    · 50 min

    This Week In Startups is made possible by: PayPal: https://paypal.com/business Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Odoo: https://Odoo.com/twist Today’s show: Wall…

  15. A rogue OpenAI agent hacked Australia’s government. Does this matter? | E2342

    · 1 h 26 min

    This Week In Startups is made possible by: Lightfield: https://lightfield.app Paper: https://getpaper.ai/twist The Conservation Fund: https://conservationfund.org/ Plaud: https://plaud.ai/twist Athena:…

  16. VCs Would Bet on Open-Source AI Over OpenAI and Anthropic | E2341

    · 1 h 27 min

    This Week In Startups is made possible by: Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Odoo: https://odoo.com/twist Rippling: https://rippling.ai/twist Plaud:…

  17. Elon's New Hyperloop, Trump's AI Rename, and a Model That Won't Talk | E2340

    · 1 h 10 min

    This Week In Startups is made possible by: Vanta: https://www.vanta.com/twist DigitalOcean: https://do.co/twist Lightfield: https://lightfield.app Plaud: https://plaud.ai/twist Today’s show: Elon revives the…

  18. Hugging Face Co-Founder on Open-Source, Microduck, and NVIDIA | E2339

    · 1 h 34 min

    This Week In Startups is made possible by: Superhuman: https://superhuman.com/ Paypal: https://paypal.com/business Odoo: https://odoo.com/twist Plaud: https://plaud.ai/twist Harmonic: https://harmonic.ai/twist…

  19. 90% of AI prototypes never reach production (w/ Temporal's Samar Abbas) | AI Basics

    · 19 min

    The TWiST AI Basics series is made possible by Google for Startups! Build context-aware AI workflows using DeepMind models and orchestration tools with Google for Startups' new Startup technical guide on generative…

  20. Ask Jason: AI Extinction, Grok's Rogue Meme Coin & Weed Farms as Data Centers | E2337

    · 1 h 11 min · Episode 2337

    This Week In Startups is made possible by: Quo: http://quo.com/TWiST The Conservation Fund: https://conservationfund.org CLA: https://www.claconnect.com/withyou Today's show: A 27-year-old Anthropic researcher…

  21. The Pentagon Wants Equity in AI Startups | E2336

    · 1 h 13 min · Episode 2336

    This Week In Startups is made possible by: DigitalOcean: https://do.co/twist Odoo: https://odoo.com/twist Upwork: https://upwork.com Today's show: The Pentagon is reportedly in talks to lend AI cloud startup…

  22. Becki DeGraw on founder vesting, advisor equity & the 4-term-sheet play

    · 23 min

    This Week In Startups is made possible by: Wilson Sonsini: https://www.wsgr.com/en/ Today's show: One of YouTube's three co-founders left for grad school and walked away with a fraction of what his partners made on…

  23. Did OpenAI Steal the Navier-Stokes Solution? | E2335

    · 1 h 21 min · Episode 2335

    This Week In Startups is made possible by: Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain NetSuite: https://www.netsuite.ai/twist Vanta: https://www.vanta.com/twist Plaud:…

  24. Dr. Mark Hyman on Function Health & GLP-1 microdosing | E2334

    · 58 min · Episode 2334

    This Week In Startups is made possible by: Odoo: https://odoo.com/twist Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Rippling: https://rippling.ai/twist Today's show: Your…

  25. Becki DeGraw on spinouts, IP licensing & clean exits | Wilson Sonsini Startup Legal Basics

    · 18 min

    This Week In Startups is made possible by: Wilson Sonsini Today's show: Spinouts are everywhere right now, and most founders get the cap table wrong. Jason sits down with Becki DeGraw, partner at Wilson Sonsini, to…

  26. VC experts on why Physical AI funding is heating up | E2333

    · 1 h 20 min · Episode 2333

    VC experts on why Physical AI funding is heating up | E2333 This Week In Startups is made possible by: partner 1 - link partner 2 - link partner 3 - link Today's show: Are we one step closer to data centers in…

  27. Are AI Agents forming "civilizations" or is this just a psy op? | 2332

    · 1 h 07 min · Episode 2332

    This Week In Startups is made possible by: Northwest Registered Agent: https://northwestregisteredagent.com/twistdomain CLA: https://www.claconnect.com/withyou Rippling: https://rippling.ai/twist Today's show:…

  28. Breaking down Nvidia's Hugging Face and Poolside bets | E2331

    · 1 h 48 min · Episode 2331

    This Week In Startups is made possible by: DigitalOcean: https://do.co/twist Every.io: https://every.io PayPal: https://paypal.com/business Today's show: *Nvidia agreed to buy Hugging Face for $12.9 billion, just…

  29. Bill Gates foresees massive AI job loss: these VCs disagree | E2330

    · 1 h 31 min · Episode 2330

    This Week In Startups is made possible by: Lightfield: https://lightfield.app Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Rippling: https://Rippling.ai/twist Today's show:…

  30. You Can't Fire a VC From Your Board: Here's Why | Wilson Sonsini Startup Legal Basics

    · 25 min

    Today's show: Can a founder actually fire a board member? Short answer: almost never. And the reason why may surprise a lot of founders. On this edition of Legal Basics, Wilson Sonsini partner Becki DeGraw joins…

  31. China wants you to cheer for the robots taking your job | E2329

    · 1 h 20 min · Episode 2329

    This Week In Startups is made possible by: Odoo: https://odoo.com/twist Quo: https://quo.com/TWiST Conservation Fund: https://conservationfund.org/ how old a movie has to be for me to be able to show a part of it…

  32. Open source is going to win it all: Harvey proves it | E2328

    · 1 h 09 min · Episode 2328

    This Week In Startups is made possible by: Superhuman: https://superhuman.com Sentry: https://sentry.io/twist Lightfield: https://lightfield.app Today's show: Jason's been saying it for years now (and we've got an…

  33. Taste is the new programming language (w/ Astrocade CEO Amir Sadeghian) | AI Basics

    · 21 min

    The TWiST AI Basics series is made possible by Google Cloud! Build context-aware AI workflows using DeepMind models and orchestration tools with Google for Startups' new Startup technical guide on generative media.…

  34. Neurosymbolic AI outperforms chatbots and product search | E2327

    · 54 min · Episode 2327

    This Week In Startups is made possible by: Vanta: https://www.vanta.com/twist Agree: https://agree.com YSecurity: https://ysecurity.io/TWIST Today's show: Frontier AI models can ace PhD-level exams, but it's still…

  35. Bittensor creator Const on Affine, dTAO, "mining reasoning," and more | E2326

    · 1 h 25 min · Episode 2326

    This Week In Startups is made possible by: Northwest Registered Agent: https://northwestregisteredagent.com/twist DigitalOcean: https://do.co/twist Odoo: https://odoo.com/twist Today's show: We've been going deep…

  36. What we'll learn from Anthropic's $2-$3T IPO | E2325

    · 1 h 20 min · Episode 2325

    This Week In Startups is made possible by: PayPal Open https://paypal.launch.co CLA https://claconnect.com/withyou Odoo https://Odoo.com/twist Today's show: *Anthropic is likely headed for the largest IPO in…

  37. These robots could cut delivery costs by 80% | Next Unicorns

    · 1 h 04 min · Episode 2324

    These robots could cut delivery costs by 80% | Next Unicorns This Week In Startups is made possible by: Squarespace https://squarespace.com/twist Northwest Registered Agent https://northwestregisteredagent.com/twist…

  38. Zuck's AI manifesto is a data center PR masterclass | E2323

    · 1 h 20 min · Episode 2323

    This Week In Startups is made possible by: Every.io https://every.io NetSuite https://NetSuite.ai/TWIST YSecurity https://YSecurity.io/TWIST Today's show: *Meta chief Mark Zuckerberg published a 6,500 word essay…

  39. How AI splits startups into winners and losers | E2322

    · 1 h 18 min · Episode 2322

    This Week In Startups is made possible by: DigitalOcean https://do.co/twist Sentry https://sentry.io/twist Lightfield https://lightfield.app Today's show: A hedge fund just blew up shorting SaaS stocks. In turns…

  40. Airtable's 80% off value crash: VCs explain why it's still a win | E2321

    · 1 h 13 min · Episode 2321

    This Week In Startups is made possible by: Vanta https://www.vanta.com/twist Agree https://agree.com Odoo https://Odoo.com/twist Today's show: *Airtable just sold for $2.25 billion, an 81% drop from its peak of…

  41. How Bespoke faked AI until it actually worked (w/ Akemi Tsunagawa) | E2320

    · 1 h 02 min · Episode 2320

    This Week In Startups is made possible by: Odoo https://Odoo.com/twist Quo https://quo.com/TWiST Northwest Registered Agent https://northwestregisteredagent.com/twist Today's show: *Before Bespoke's "travel…

  42. Why AI has no taste and how to fix it (w/ Thais Castello Branco) | E2319

    · 1 h 15 min · Episode 2319

    This Week In Startups is made possible by: YSecurity https://YSecurity.io/TWIST MongoDB https://MongoDB.com/ai Odoo https://Odoo.com/twist Today's show: AI models can solve PhD-level math equations and code an app…

  43. Banning Chinese robots isn't regulatory capture | E2318

    · 1 h 26 min

    This Week In Startups is made possible by: Northwest Registered Agent- NorthwestRegisteredAgent.com/twist Odoo - Odoo.com/twist MongoDB - MongoDB.com/ai Today's show: The FCC's decision to ban Chinese humanoid…

  44. While other cultivated meat companies are collapsing, this one turned a profit | E2317

    · 44 min · Episode 2317

    This Week In Startups is made possible by: Every.io https://every.io MongoDB https://MongoDB.com/ai Agree https://agree.com Today's show: *Most lab-grown meat companies have already gone under. It's expensive to…

  45. Why quantum has been "10 years away" for 30 years | E2316

    · 45 min · Episode 2316

    This Week In Startups is made possible by: PayPal Open https://paypalopen.com DigitalOcean https://do.co/twist Rippling https://Rippling.ai/twist Today's show: *For three decades now, we've been told that…

  46. Why this longevity startup raised in Japan, not Silicon Valley | TWiST Tokyo | E2315

    · 1 h 12 min · Episode 2314

    This Week In Startups is made possible by: Sentry https://sentry.io/twist Agree https://agree.com Northwest Registered Agent https://northwestregisteredagent.com/twist Today's show: French ex-martial artist Bilal…

  47. The AI Securing Your Workforce Before a Mistake Ever Becomes a Breach | E2314

    · 42 min · Episode 2314

    This Week In Startups is made possible by: Vanta https://www.vanta.com/twist Superhuman https://superhuman.com YSecurity https://YSecurity.io/TWIST Today's show: *Cybersecurity has long focused on cleaning up a…

  48. The dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313

    · 47 min · Episode 2313

    The dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313 This Week In Startups is made possible by: Northwest Registered Agent https://northwestregisteredagent.com/twist CLA…

  49. A Startup Is Trying to Buy PayPal… Craziest Deal of 2026! | E2312

    · 1 h 14 min · Episode 2312

    This Week In Startups is made possible by: MongoDB - MongoDB.com/ai Rippling - Rippling.ai/twist Agree.com - agree.com Today's show: Hustle Fund's Eric Bahn and Chapter One's Jeff Morris Jr. join our venture…

  50. Jason turned $11 and one tweet into 1.1M views | E2311

    · 1 h 30 min · Episode 2311

    This Week In Startups is made possible by: Quo https://quo.com/TWiST PayPal Open https://paypalopen.com Northwest Registered Agent https://northwestregisteredagent.com/twist Today's show: *Jason spent $11 building…

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