The Science of Drug Discovery: Insights from Artem Evdokimov
· 2 h 50 min · Episode 5
Episode The Science of Drug Discovery: Insights from Artem Evdokimov
In this episode, drug discovery scientist Artem Evdokimov discusses the science of pharmaceutical development, from historical breakthroughs to the current landscape. He shares insights on antibiotics resistance, the obesity drug Ozempic, and technical details of drug screening methods like DNA-encoded libraries.
The conversation covers the economics of drug development, the potential of AI, and broader philosophical questions about human health and medicine. Evdokimov emphasizes the importance of avoiding oversimplification in science while highlighting both the triumphs and ongoing challenges in pharmaceutical research.
03:18 Historical Roots of Medicine 05:33 Evolution of Drug Delivery Methods 12:52 Modern Drug Discovery and Challenges 45:39 Understanding the Drug Discovery Process 47:30 Challenges in Gene Therapy 49:26 Complexities of Human Physiology 53:14 The Role of Receptors and Hormones 01:28:12 The Selenium Shortage and Shampoo Dilemma 01:28:54 Challenges in Drug Manufacturing and Distribution 01:34:23 Antibiotic Resistance: A Growing Concern 01:45:18 The Future of Drug Discovery and AI 02:11:01 Exploring AI and Drug Discovery 02:11:41 Outsourcing in Pharma: Pros and Cons 02:13:56 High Throughput Screening and Machine Learning 02:16:37 Challenges and Future of Drug Discovery
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