Podcasts · Technology · Health & Fitness
NEJM AI Grand Rounds
NEJM Group
48 episodes
NEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You’ll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations will enlighten and surprise you as we journey through this very exciting field. Produced by NEJM Group.
Episodes
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Abridge’s Dr. Michal Nedoszytko on Physicians Who Build Software
Dr. Michał Nedoszytko, clinician scientist at Abridge and interventional cardiologist, has spent two decades building software alongside clinical practice. He explains how AI can help physicians gather better…
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Beyond the Hype: Dr. Xiao Liu on Evaluating Medical AI
The promise of medical AI is not simply better performance — it is better care grounded in evidence patients and clinicians can trust. Dr. Xiao Liu, a clinician and medical AI researcher affiliated with the University…
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Dr. Suchi Saria on Building AI That Changes Care
A patient can deteriorate while the warning signs remain buried in a noisy electronic record. Dr. Suchi Saria, Founder and CEO of Bayesian Health and a faculty member at Johns Hopkins University, has spent her career…
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Weave’s Brandon Rice on Rebuilding Drug Regulation with AI
Brandon Rice believes that improving health care sometimes means improving the systems behind it. Through his work at Weave, he focuses on modernizing the regulatory infrastructure that helps bring new medicines to…
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OpenAI’s Karan Singal on HealthBench and the Future of Medical AI
Medical expertise has always been scarce. Dr. Karan Singal believes AI can help change that. Drawing on his work at OpenAI and earlier efforts behind Med‑PaLM, he discusses how clinicians and patients are already using…
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The OpenEvidence Episode: Dr. Travis Zack on the Future of Clinical Evidence
Dr. Travis Zack, Chief Medical Officer of OpenEvidence, takes us behind the scenes of the start and growth of the company, and brings a clinician’s perspective to one of medicine’s hardest questions: how should…
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Doctronic’s Autonomous AI with Dr. Byron Crowe
Doctronic CMO Dr. Byron Crowe describes how administrative complexity can interfere with timely, effective treatment, and how AI may help address those challenges. Crowe discusses Doctronic’s use of autonomous AI to…
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AI’s Next Frontier with Dr. Kyunghyun Cho
Dr. Kyunghyun Cho is a leading AI researcher best known for co-authoring a landmark 2014 paper that introduced neural machine translation. In this episode, he discusses his wide-ranging career spanning fundamental AI…
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Epic’s Approach to AI with Seth Hain
Clinical AI only helps patients if clinicians and health systems trust it. Seth Hain describes how Epic is building foundation models that respect institutional autonomy, minimize burden, and prioritize safety. He…
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Bridging AI and Biology to Tackle Medicine’s Hardest Problems with Dr. Marinka Zitnik
For Dr. Marinka Zitnik, the promise of AI in medicine begins with acknowledging the scale of the problem. Most patients with rare diseases have no approved treatments, and traditional drug development timelines make…
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What Values are in AI? A Conversation with Dr. Zak Kohane
For Dr. Zak Kohane, this year’s advances in AI weren’t abstract. They were personal, practical, and deeply tied to care. After decades studying clinical data and diagnostic uncertainty, he finds himself building his…
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From Hindsight Bias to Machine Bias: Dr. Laura Zwaan on Learning from Mistakes
As a cognitive psychologist, Dr. Laura Zwaan studies how humans make—and learn from—mistakes. In this episode of NEJM AI Grand Rounds, she brings that lens to AI, showing how machines inherit our biases and why both…
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Medicine, Machines, and Magic: Dr. Jonathan Chen on Medical AI
In this episode, Dr. Jonathan Chen joins the hosts to discuss his path from teenage programmer to Stanford physician-informatician and why machine learning has both thrilled and unnerved him. From his 2017 NEJM essay…
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From Clinician to Chief Health AI Officer: A Conversation with Dr. Karandeep Singh
Dr. Karandeep Singh brings two worlds together: programming and medicine. In this conversation, he explains how early experiments with code led him to biomedical informatics, why gaps between paper performance and…
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Radiologist Turned CEO: Dr. Jeremy Friese on AI for Prior Authorization
Dr. Jeremy Friese knows medicine from both sides. A practicing radiologist and technology executive, he’s seen firsthand how administrative burden undermines care. In this episode of NEJM AI Grand Rounds, he walks…
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Can AI Accelerate Science? Dr. Andy Beam on AI’s Next Frontier
Dr. Andy Beam has trained models, mentored scientists, and used data to quantify the value of treatments. In this episode of NEJM AI Grand Rounds, Raj Manrai turns the table on his co-host, reflecting on how Andy’s…
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Google’s Efforts to Build Patient-Facing AI: A Conversation with Drs. Alan Karthikesalingam and Anil Palepu
In this episode of NEJM AI Grand Rounds, guests Drs. Alan Karthikesalingam and Anil Palepu of Google walk co-hosts Raj Manrai and Andy Beam through the making and evaluation of AMIE, an AI system designed to conduct…
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Rewriting the Clinical Playbook: Dr. Shiv Rao on Scaling Empathy with AI
Dr. Shiv Rao, cardiologist and CEO of Abridge, joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds for an inspiring conversation at the intersection of medicine, technology, and meaning. Shiv shares the origin…
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Pixels to Protocols: Building the AI Future of Pathology with Dr. Faisal Mahmood
Dr. Faisal Mahmood, Associate Professor of Pathology at Brigham and Women’s Hospital and Harvard Medical School, joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds to explore the frontier of computational…
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From Bedside to Boardroom: How AI, Multi-Omics, and New Business Models Are Shaping the Biomedical Frontier with Morgan Cheatham
Morgan Cheatham joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds to discuss the evolving landscape of artificial intelligence in health care, from its role in automating clinical documentation to its…
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From Clinical Notes to GPT-4: Dr. Emily Alsentzer on Natural Language Processing in Medicine
Dr. Emily Alsentzer joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds to discuss the evolution of natural language processing (NLP) in medicine. A Stanford faculty member and expert in clinical AI, Emily…
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Health Care at the Breaking Point: Dr. Zak Kohane Returns to NEJM AI Grand Rounds
In this return appearance on NEJM AI Grand Rounds, Dr. Zak Kohane joins hosts Raj Manrai and Andy Beam to discuss the evolving landscape of AI in medicine. As the first repeat guest on the show, Dr. Kohane shares…
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The Economics of AI: A Conversation with Larry Summers
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Larry Summers about artificial intelligence’s transformative potential and its implications for society. The conversation explores…
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Partners in Diagnosis: ChatGPT, a Mother’s Intuition, and a Doctor’s Expertise with Courtney Hofmann and Dr. Holly Gilmer
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Courtney Hofmann, a mother whose use of ChatGPT led to her son’s diagnosis of tethered cord syndrome after seeing 17 doctors over three…
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The Pulse of Progress: AI in Cardiology with Dr. David Ouyang
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. David Ouyang, a cardiologist and AI researcher at Cedars-Sinai Medical Center. The conversation explores Ouyang’s journey from…
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AI at the Frontlines: Dissecting Clalit’s Roadmap for the Future of Public Health with Noa Dagan and Ran Balicer
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. Noa Dagan and Dr. Ran Balicer from the Clalit Research Institute in Israel. The conversation explores Clalit’s groundbreaking work…
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From Petri Dishes to Pitch Decks: Cultivating Health Care’s AI Future with Vijay Pande
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. Vijay Pande, a general partner at Andreessen Horowitz (A16Z) where he leads investments in health care and life sciences. The…
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Love and Large Language Models: Voices of the Future with Dr. Rohaid Ali and Dr. Fatima Mirza
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. Rohaid Ali and Dr. Fatima Mirza, a married couple and chief residents at Brown University. The conversation explores their…
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AI and the Evolution of Medical Thought with Dr. Adam Rodman
In this episode of the AI Grand Rounds podcast, Dr. Adam Rodman shares his unique journey from a historian to a physician deeply interested in the intersection of medicine and artificial intelligence. He highlights his…
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Translational AI in Medicine: Unlocking AI’s Potential in Health Care with Nigam Shah
In this episode of the NEJM AI Grand Rounds podcast, Dr. Nigam Shah, a distinguished Professor of Medicine at Stanford University and inaugural Chief Data Scientist for Stanford Health Care, shares his journey from…
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From Theory to Therapy: The Evolution of AI in Medicine with Dr. Daphne Koller
In this episode of the AI Grand Rounds podcast, Dr. Daphne Koller charts her professional trajectory, tracing her early fascination with computers to her influential role in AI and health care. Initially intrigued by…
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From Single Neurons to AI Systems: The Evolution of Decision Sciences in Medicine with Dr. Eric Horvitz
In this episode of the AI Grand Rounds podcast, Dr. Eric Horvitz describes his career evolution from an interest in neurobiology to significant contributions in AI, particularly in understanding complex systems and…
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AI Frontiers with James Zou: The Future of Multi-Modal AI in Medicine
In this episode of the AI Grand Rounds podcast, Dr. James Zou shares his personal journey to discovering machine learning during his graduate studies at Harvard. Fascinated by the potential of AI and its application to…
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Interrogating AI Fairness and Bias in Dermatology and Beyond with Dr. Roxana Daneshjou
In this episode of the AI Grand Rounds podcast, Dr. Roxana Daneshjou shares her journey from a childhood influenced by early exposure to science to her current role as an assistant professor at Stanford. Her path…
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Medicine as a Knowledge Processing Discipline with Dr. Zak Kohane
In this episode, Dr. Zak Kohane shares his journey into AI and medicine, reflecting on early influences from science fiction authors and programming experiences in his youth. He discusses his academic path, moving from…
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Examining Open-Source Frameworks and AI in Medicine with Interventional Radiologist Dr. Judy Gichoya
In this episode, Dr. Judy Wawira Gichoya, Associate Professor in the Department of Radiology and Imaging Sciences at Emory University School of Medicine, details her journey from Kenya to the United States, from…
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Machines & Genes: The Future of AI in Biology with Dr. George Church
In this episode, vanguard geneticist Dr. George Church recounts his storied career from his early fascination with computers and science to his pioneering work in genomics and synthetic biology. Dr. Church developed…
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Mark Cuban on AI, Trust in Health Care, and Skip Bayless
In this episode, we’re joined by business magnate and investor Mark Cuban. Cuban describes his journey from humble beginnings as a self-taught programmer to becoming a successful serial entrepreneur and owner of an NBA…
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An Iron Fist in a Velvet Glove: A Conversation with Dr. Atul Butte
In this episode, pioneering informatician Dr. Atul Butte guides listeners through his storied career, from his early days as a pediatric endocrinologist and informatician in Boston to his trailblazing work on the West…
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The Double-Edged Sword of AI, with Dr. Ziad Obermeyer
In this thought-provoking episode, Dr. Ziad Obermeyer delves into the complex issues of bias, safety, and generalizability of medical AI. Dr. Obermeyer emphasizes the importance of machine learning researchers’ task…
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Can AI Be Harmful? A Conversation with MIT’s Dr. Marzyeh Ghassemi
Dr. Marzyeh Ghassemi has been at the forefront of medical machine learning for several years. In this episode, she describes her group’s work and her perspectives on developing and applying machine learning to…
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Google’s Exploration of Large Language Models in Medicine
Large language models (LLMs) like ChatGPT have proven highly capable of a broad array of natural language tasks including summarizing text, generating prose, and answering questions. This episode’s two guests, Dr. Alan…
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No Doctor Needed? Dr. Michael Abramoff on the Potential of Autonomous AI
Dr. Michael Abramoff is a renowned ophthalmologist and medical AI pioneer. In this episode, we explore his groundbreaking work that led to the first FDA-authorized device that does not require a physician, IDx-DR,…
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The GPT-4 Episode: Microsoft’s Peter Lee on the Future of Language Models in Medicine
Dr. Peter Lee has shaped computer science from academia, government, and industry. He has chaired a major computer science department, built a new technology office at DARPA, and now serves as Corporate Vice President…
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Dr. Lily Peng: AI for Ophthalmology and the Challenges of AI in the Real World
Dr. Lily Peng has driven major medical AI efforts along the long and arduous path from ideation to deployment. From publishing a landmark study in 2016 presenting an AI model to detect diabetic retinopathy in retinal…
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Dr. Pranav Rajpurkar on AI and Radiology
Dr. Pranav Rajpurkar has been at the forefront of medical AI for his entire career. As a graduate student in computer science at Stanford, he created some of the first AI models for radiology and created a suite of…
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Dr. Euan Ashley on AI, Genomics, and Cardiology
Dr. Euan Ashley is a pioneer. In 2010, he led the team that conducted the first clinical interpretation of a human genome, and he holds the record for the world’s fastest genomic diagnosis. He even has a Guinness World…
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Trailer: Introducing NEJM AI Grand Rounds Podcast
[Transcript] How will AI change clinical practice and healthcare, and how will it impact the patient experience? Who are the people pushing for change and what are their goals? These are just a few of the topics that…
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