搞乜咁科學 #11 - 2022新發現 New in 22’🗓
· 1 h 00 min · S1 E11
Episode 搞乜咁科學 #11 - 2022新發現 New in 22’🗓
歡迎嚟到 搞乜咁科學 GMG Science 第11集！
今集嘅主題係2022新發現 New in 22’🗓！Keith會講數學家點樣將個圓形變成正方形，Abellona會解釋有咩方法製造到萬能嘅流感疫苗?
喂！好奇心，係時候醒喇 :)
Social Media:
科學一齊搞 Got Something for GMG - 有咩想同我哋講都可以係度share㗎
搞乜咁科學網頁 搞乜咁科學 IG 搞乜咁科學 YouTube Abellona IG Keith IG Keith YouTube
Show Notes and Links:
大部份今集有關嘅圖片會係我哋IG見到㗎
Keith’s part
學寫電腦程式竟然同學語言能力有關﹐反而同數感無乜關係? - Prat, C. S., et al. (2020). Relating natural language aptitude to individual differences in learning programming languages. Scientific reports, 10(1), 1-10.
較剪全等 Scissor Congruence - nLab
三大尺規作圖問題 Impossible Constructions - Wikipedia
正方形原來係剪唔到變圓形㗎…
Dubins, L., Hirsch, MW, & Karush, J. (1963). Scissor congruence. Israel Journal of Mathematics, 1(4), 239-247.
可等分解 Equidecomposable - Wolfram MathWorld
…但分解佢就得喇!
Laczkovich, M. (1990). Equidecomposability and discrepancy; a solution of Tarski's circle-squaring problem. , 1990(404), 77-117.
宇宙有幾多原子？好多囉 - US Department of Energy’s Jefferson Lab
🟥 ➡️ 🔴 嘅進展
Grabowski, L., Máthé, A., & Pikhurko, O. (2016). Measurable equidecompositions for group actions with an expansion property, accepted by J. Eur. Math. Soc., E-print arxiv, 1601.
Marks, A. S., & Unger, S. T. (2017). Borel circle squaring. Annals of Mathematics, 186(2), 581-605.
終於變到喇!
Máthé, A., Noel, J. A., & Pikhurko, O. (2022). Circle Squaring with Pieces of Small Boundary and Low Borel Complexity. arXiv preprint arXiv:2202.01412.
正方形點變做圓形，去片!
Abellona’s part
過去一百年的流感大流行歷史 – CDC
流感病毒的結構
現時的流感疫苗是怎樣製造的
流感病毒撠手的地方: Antigen shift 抗原轉變 & Antigen drift 抗原飄移
研發萬能流感疫苗的策略
策略一: 同時針對多種HA亞種的mRNA疫苗
Arevalo, C.P., et al, 2022. A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes. Science, 378(6622), pp.899-904.
策略二: 誘使免疫系統針對HA的莖部的疫苗
Nachbagauer, R., et al., 2021. A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial. Nature medicine, 27(1), pp.106-114.
策略三: 針對流感病毒表面的其他蛋白
Kim, K.H., et al., 2022. Universal protection against influenza viruses by multi-subtype neuraminidase and M2 ectodomain virus-like particle. PLoS pathogens, 18(8), p.e1010755.
Links in the notes 15
- https://forms.gle/26RSEgW9NeeSMc4a7
- https://www.youtube.com/channel/UCFj2cwjDASS2SyYsj3pkNSQ
- https://youtube.com/c/KeithPoonSir
- https://ncatlab.org/nlab/show/scissors+congruence
- https://en.wikipedia.org/wiki/Straightedge_and_compass_construction#Impossible_constructions
- https://mathworld.wolfram.com/Equidecomposable.html
- https://education.jlab.org/qa/mathatom_05.html
- https://www.quantamagazine.org/an-ancient-geometry-problem-falls-to-new-mathematical-techniques-20220208/
- https://www.cdc.gov/flu/pandemic-resources/basics/past-pandemics.html
- https://www.virology.ws/2009/04/30/structure-of-influenza-virus/
- https://www.understandinganimalresearch.org.uk/news/how-are-flu-vaccines-made
- https://www.technologynetworks.com/immunology/articles/antigenic-drift-vs-antigenic-shift-311044
- https://www.science.org/doi/10.1126/science.abm0271
- https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00056-1/fulltext
- https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010755
Transcript
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