Podcasts · The Dr Louise Newson Podcast
113 – Does menopause speed up ageing? What estrogen does to inflammation
· 32 min · S2 E113
Episode 113 – Does menopause speed up ageing? What estrogen does to inflammation
Does menopause speed up ageing? The science shows inflammation accelerates in perimenopause, and estrogen can slow it.
Nikolina Lauc is CEO of GlycanAge, which measures a marker of low-grade inflammation in our antibodies, building on research her father has dedicated his scientific career to. Nikolina’s research shows estrogen can prevent, and even reverse, the rise in inflammation that comes with menopause.
Dr Louise Newson explains why so many chronic diseases, from heart disease to dementia, are driven by inflammation, why estrogen is being overlooked in the longevity conversation and what happens to women whose ovaries are removed young and are never given hormones back. They also discuss why inflammation soars after childbirth, and how progesterone can be used to treat postnatal depression.
Nikolina closes with three things she wants research to answer next, from personalising HRT doses to whether therapy can calm inflammation.
Follow Nikolina: @nikolinalauc
Let’s connect 👉I've written a whole chapter on inflammation and hormones in my book, The Powerof Hormones: https://bio.to/ThePowerofHormones?utm_source=DLN&utm_medium=biolink&utm_campaign=crosspromo 👉 Follow the podcast on Spotify or Apple Podcasts so you never miss an episode 👉More from Dr Louise Newson: https://linkin.bio/drlouisenewson
Chapters
00:00 Why does inflammation matter for women? 01:34 What is low-grade inflammation? 03:33 When does inflammation turn against us? 06:05 What is "inflammaging"? 08:12 What does a glycan test measure? 08:46 Does inflammation speed up in perimenopause? 10:43 Are oestrogen and testosterone really sex hormones? 12:12 Does inflammation change across the cycle? 13:31 What happens when ovaries are removed young? 15:35 Why does inflammation soar after birth? 16:29 Could progesterone help postnatal depression? 20:33 Can grief and divorce age your immune system? 21:30 Are hormones medicine's biggest advance? 24:19 Is HRT's benefit just placebo? 25:19 Can inflammation predict disease years early? 29:05 What makes some people resilient to disease? 30:05 Are women on the right dose of HRT? 31:26 What should hormone research answer next? 32:13 Does testosterone affect inflammation? 33:05 Can therapy reduce inflammation?
Links in the notes 2
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