Podcasts · Technology · News
The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)
Sam Charrington
300 episodes
Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.
Episodes page 1 of 6
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Airbnb Is Building a ‘Company Brain’ for AI Agents with Ahmad Al-Dahle - #781
AI agents need the institutional knowledge experienced employees rely on: why a system works a certain way, which policies apply, and what never made it into the documentation. Capturing that knowledge is hard. Keeping…
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Your Ranking Model Is Optimizing the Wrong Thing with Zoe Weil - #780
In this episode, Zoe Weil, co-founder and CEO of Sequen, joins us to discuss how ranking systems can use live behavioral signals to optimize for purchases rather than clicks or search relevance alone. Zoe explains why…
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Why Jev Is Changing How We Build With AI with Diogo Almeida - #779
In this episode, Diogo Almeida, co-founder and CEO of TypeSafe, joins us to discuss Jev, TypeSafe’s recently released model for bringing fast, reliable intelligence directly into software. We explore the idea of…
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From Math Olympiads to Navier-Stokes: How Fast Is AI Progressing? with Greg Burnham - #778
AI systems have gone from struggling with grade-school math to helping solve research problems that have resisted mathematicians for decades, including Navier-Stokes. In this episode, Greg Burnham, who leads AI…
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From Voice Agents to AI Avatars with Alexander Smola - #777
Voice AI has gotten remarkably good, but natural conversation remains a high bar. Small delays, awkward interruptions, or the wrong tone can quickly break the illusion—and adding vision and visual presence only raises…
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Do AI Tokenomics Matter More Than Model Benchmarks? with Chris Potts - #776
As reasoning models consume more tokens and AI systems become more expensive to run, understanding what those tokens actually buy is becoming increasingly important. In this episode, Stanford professor and Big Spin…
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World Models and the Future of Spatial AI with Justin Johnson - #775
In this episode, Justin Johnson, co-founder of World Labs, joins us to discuss world models and the emerging field of spatial AI. We explore why many researchers see capabilities beyond language as an important…
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Why the Next AI Breakthrough May Come from Physics with Max Welling - #774
The conventional wisdom in AI is that the next breakthrough will come from more compute, more data, and larger models. But what if the next leap comes from somewhere else? In this episode, Max Welling—co-founder and…
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Why Image Generation Needs More Than Bigger Models with Fatih Porikli - #773
Text-to-image models have become remarkably good at producing realistic images. But realism isn’t the same as correctness. Ask for several distinct people, a specific composition, or a high-resolution image generated…
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Why Models Are AI’s Next Training Dataset with Damian Borth - #772
For more than a decade, AI has advanced by training ever-larger models on ever-larger datasets. But as high-quality training data becomes harder to find and pretraining grows increasingly expensive, researchers are…
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How AI Learns to Smell with Alex Wiltschko - #771
In this episode, Alex Wiltschko, founder and CEO of Osmo, joins the show to discuss his goal of giving computers a sense of smell and what it takes to build olfactory intelligence. We explore the science behind smell,…
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Why AI Agents Break the GenAI Security Model with Devvret Rishi - #770
In this episode, Sam talks with Dev Rishi, GM of AI at Rubrik, about what happens when agents move beyond answering questions and start taking action across tools, systems, and business processes. We explore why the…
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Is RAG Dead? Lessons from Building AI for Tax Law with Alex Bowcut - #769
As context windows grow into the millions of tokens, many AI practitioners are questioning whether retrieval-augmented generation (RAG) is still necessary. If modern models can ingest entire libraries of documents, why…
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Relational Foundation Models for Enterprise Data with Jure Leskovec - #768
In this episode, Jure Leskovec, co-founder and chief scientist at Kumo and professor of computer science at Stanford, joins us to explore two fronts of his work: AI for science and relational deep learning. We begin…
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How to Find the Agent Failures Your Evals Miss with Scott Clark - #767
In this episode, Scott Clark, co-founder and CEO of Distributional, joins us to explore how teams can reliably operate and improve complex LLM systems and agents in production. Scott introduces a Maslow’s hierarchy of…
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How to Engineer AI Inference Systems with Philip Kiely - #766
In this episode, Philip Kiely, head of AI education at Baseten, joins us to unpack the fast-evolving discipline of inference engineering. We explore why inference has become the stickiest and most critical workload in…
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How Capital One Delivers Multi-Agent Systems with Rashmi Shetty - #765
In this episode, Rashmi Shetty, senior director of enterprise generative AI platform at Capital One, joins us to explore how the company is designing, deploying, and scaling multi-agent systems in a highly regulated…
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The Race to Production-Grade Diffusion LLMs with Stefano Ermon - #764
Today, we're joined by Stefano Ermon, associate professor at Stanford University and CEO of Inception Labs to discuss diffusion language models. We dig into how diffusion approaches—traditionally used for images—are…
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Agent Swarms and Knowledge Graphs for Autonomous Software Development with Siddhant Pardeshi - #763
In this episode, Sid Pardeshi, co-founder and CTO of Blitzy, joins us to discuss building autonomous development systems able to deliver production-ready software at enterprise scale. Sid contrasts AI-assisted coding…
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AI Trends 2026: OpenClaw Agents, Reasoning LLMs, and More with Sebastian Raschka - #762
In this episode, Sebastian Raschka, independent LLM researcher and author, joins us to break down how the LLM landscape has changed over the past year and what is likely to matter most in 2026. We discuss the shift…
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The Evolution of Reasoning in Small Language Models with Yejin Choi - #761
Today, we're joined by Yejin Choi, professor and senior fellow at Stanford University in the Computer Science Department and the Institute for Human-Centered AI (HAI). In this conversation, we explore Yejin’s recent…
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Intelligent Robots in 2026: Are We There Yet? with Nikita Rudin - #760
Today, we're joined by Nikita Rudin, co-founder and CEO of Flexion Robotics to discuss the gap between current robotic capabilities and what’s required to deploy fully autonomous robots in the real world. Nikita…
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Rethinking Pre-Training for Agentic AI with Aakanksha Chowdhery - #759
Today, we're joined by Aakanksha Chowdhery, member of technical staff at Reflection, to explore the fundamental shifts required to build true agentic AI. While the industry has largely focused on post-training…
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Why Vision Language Models Ignore What They See with Munawar Hayat - #758
In this episode, we’re joined by Munawar Hayat, researcher at Qualcomm AI Research, to discuss a series of papers presented at NeurIPS 2025 focusing on multimodal and generative AI. We dive into the persistent…
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Scaling Agentic Inference Across Heterogeneous Compute with Zain Asgar - #757
In this episode, Zain Asgar, co-founder and CEO of Gimlet Labs, joins us to discuss the heterogeneous AI inference across diverse hardware. Zain argues that the current industry standard of running all AI workloads on…
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Proactive Agents for the Web with Devi Parikh - #756
Today, we're joined by Devi Parikh, co-founder and co-CEO of Yutori, to discuss browser use models and a future where we interact with the web through proactive, autonomous agents. We explore the technical challenges…
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AI Orchestration for Smart Cities and the Enterprise with Robin Braun and Luke Norris - #755
Today, we're joined by Robin Braun, VP of AI business development for hybrid cloud at HPE, and Luke Norris, co-founder and CEO of Kamiwaza, to discuss how AI systems can be used to automate complex workflows and unlock…
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Building an AI Mathematician with Carina Hong - #754
In this episode, Carina Hong, founder and CEO of Axiom, joins us to discuss her work building an "AI Mathematician." Carina explains why this is a pivotal moment for AI in mathematics, citing a convergence of three key…
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High-Efficiency Diffusion Models for On-Device Image Generation and Editing with Hung Bui - #753
In this episode, Hung Bui, Technology Vice President at Qualcomm, joins us to explore the latest high-efficiency techniques for running generative AI, particularly diffusion models, on-device. We dive deep into the…
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Vibe Coding's Uncanny Valley with Alexandre Pesant - #752
Today, we're joined by Alexandre Pesant, AI lead at Lovable, who joins us to discuss the evolution and practice of vibe coding. Alex shares his take on how AI is enabling a shift in software development from typing…
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Dataflow Computing for AI Inference with Kunle Olukotun - #751
In this episode, we're joined by Kunle Olukotun, professor of electrical engineering and computer science at Stanford University and co-founder and chief technologist at Sambanova Systems, to discuss reconfigurable…
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Recurrence and Attention for Long-Context Transformers with Jacob Buckman - #750
Today, we're joined by Jacob Buckman, co-founder and CEO of Manifest AI to discuss achieving long context in transformers. We discuss the bottlenecks of scaling context length and recent techniques to overcome them,…
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The Decentralized Future of Private AI with Illia Polosukhin - #749
In this episode, Illia Polosukhin, a co-author of the seminal "Attention Is All You Need" paper and co-founder of Near AI, joins us to discuss his vision for building private, decentralized, and user-owned AI. Illia…
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Inside Nano Banana 🍌 and the Future of Vision-Language Models with Oliver Wang - #748
Today, we’re joined by Oliver Wang, principal scientist at Google DeepMind and tech lead for Gemini 2.5 Flash Image—better known by its code name, “Nano Banana.” We dive into the development and capabilities of this…
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Is It Time to Rethink LLM Pre-Training? with Aditi Raghunathan - #747
Today, we're joined by Aditi Raghunathan, assistant professor at Carnegie Mellon University, to discuss the limitations of LLMs and how we can build more adaptable and creative models. We dig into her ICML 2025…
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Building an Immune System for AI Generated Software with Animesh Koratana - #746
Today, we're joined by Animesh Koratana, founder and CEO of PlayerZero to discuss his team’s approach to making agentic and AI-assisted coding tools production-ready at scale. Animesh explains how rapid advances in…
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Autoformalization and Verifiable Superintelligence with Christian Szegedy - #745
In this episode, Christian Szegedy, Chief Scientist at Morph Labs, joins us to discuss how the application of formal mathematics and reasoning enables the creation of more robust and safer AI systems. A pioneer behind…
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Multimodal AI Models on Apple Silicon with MLX with Prince Canuma - #744
Today, we're joined by Prince Canuma, an ML engineer and open-source developer focused on optimizing AI inference on Apple Silicon devices. Prince shares his journey to becoming one of the most prolific contributors to…
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Genie 3: A New Frontier for World Models with Jack Parker-Holder and Shlomi Fruchter - #743
Today, we're joined by Jack Parker-Holder and Shlomi Fruchter, researchers at Google DeepMind, to discuss the recent release of Genie 3, a model capable of generating “playable” virtual worlds. We dig into the…
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Closing the Loop Between AI Training and Inference with Lin Qiao - #742
In this episode, we're joined by Lin Qiao, CEO and co-founder of Fireworks AI. Drawing on key lessons from her time building PyTorch, Lin shares her perspective on the modern generative AI development lifecycle. She…
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Context Engineering for Productive AI Agents with Filip Kozera - #741
In this episode, Filip Kozera, founder and CEO of Wordware, explains his approach to building agentic workflows where natural language serves as the new programming interface. Filip breaks down the architecture of…
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Infrastructure Scaling and Compound AI Systems with Jared Quincy Davis - #740
In this episode, Jared Quincy Davis, founder and CEO at Foundry, introduces the concept of "compound AI systems," which allows users to create powerful, efficient applications by composing multiple, often diverse, AI…
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Building Voice AI Agents That Don’t Suck with Kwindla Kramer - #739
In this episode, Kwindla Kramer, co-founder and CEO of Daily and creator of the open source Pipecat framework, joins us to discuss the architecture and challenges of building real-time, production-ready conversational…
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Distilling Transformers and Diffusion Models for Robust Edge Use Cases with Fatih Porikli - #738
Today, we're joined by Fatih Porikli, senior director of technology at Qualcomm AI Research for an in-depth look at several of Qualcomm's accepted papers and demos featured at this year’s CVPR conference. We start with…
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Building the Internet of Agents with Vijoy Pandey - #737
Today, we're joined by Vijoy Pandey, SVP and general manager at Outshift by Cisco to discuss a foundational challenge for the enterprise: how do we make specialized agents from different vendors collaborate…
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LLMs for Equities Feature Forecasting at Two Sigma with Ben Wellington - #736
Today, we're joined by Ben Wellington, deputy head of feature forecasting at Two Sigma. We dig into the team’s end-to-end approach to leveraging AI in equities feature forecasting, covering how they identify and create…
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Zero-Shot Auto-Labeling: The End of Annotation for Computer Vision with Jason Corso - #735
Today, we're joined by Jason Corso, co-founder of Voxel51 and professor at the University of Michigan, to explore automated labeling in computer vision. Jason introduces FiftyOne, an open-source platform for…
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Grokking, Generalization Collapse, and the Dynamics of Training Deep Neural Networks with Charles Martin - #734
Today, we're joined by Charles Martin, founder of Calculation Consulting, to discuss Weight Watcher, an open-source tool for analyzing and improving Deep Neural Networks (DNNs) based on principles from theoretical…
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Google I/O 2025 Special Edition - #733
Today, I’m excited to share a special crossover edition of the podcast recorded live from Google I/O 2025! In this episode, I join Shawn Wang aka Swyx from the Latent Space Podcast, to interview Logan Kilpatrick and…
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RAG Risks: Why Retrieval-Augmented LLMs are Not Safer with Sebastian Gehrmann - #732
Today, we're joined by Sebastian Gehrmann, head of responsible AI in the Office of the CTO at Bloomberg, to discuss AI safety in retrieval-augmented generation (RAG) systems and generative AI in high-stakes domains…
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