Course11510112165 lectures
Physics of Biological Systems
Prof. Mithun Mitra · IIT Bombay
Lectures
Week 1
- Lecture 1: Introduction
- Lecture 2: DNA packing and structure
- Lecture 3: Shape and function
- Lecture 4: Numbers and sizes
- Lecture 5: Spatial scales and System variation
- Lecture 6: Timescales in Biology
Week 2
- Lecture 7: Random walks and Passive diffusion
- Lecture 8: Random walks to model Biology
- Lecture 9: Derivation of FRAP equations
- Lecture 10: Drift-diffusion equations
- Lecture 11: Solutions of the drift-diffusion equations
- Lecture 12: The cell signaling problem
Week 3
- Lecture 13: Cell Signalling and Capture Probability of absorbing sphere
- Lecture 14: Capture probability of reflecting sphere
- Lecture 15: Mean capture time
- Lecture 16: Introduction to fluids, viscosity and reynolds number
- Lecture 17: Introduction to the navier stokes equation
- Lecture 18: Understanding reynolds number
Week 4
- Lecture 19: Life at low reynolds number
- Lecture 20: Various phenomena at low reynolds number
- Lecture 21: Bacterial flagellar motion
- Lecture 22: Rotating flagellum
Week 5
- Lecture 23: Energy and equilibrium
- Lecture 24: Binding problems
- Lecture 25: Transcription and translation
- Lecture 26: Internal states of macromolecules
- Lecture 27: Protein modification problem
- Lecture 28: Haemoglobin-Oxygen binding problem
Week 6
- Lecture 29: Freely jointed polymer model
- Lecture 30: Entropic springs and persistence length
- Lecture 31: Freely rotating chain model and radius of gyration
- Lecture 32: The hierarchical chromatin packing model
- Lecture 33: FISH & DNA looping
- Lecture 34: Nucleosomes as barriers, Hi-C, and contact probabilities
Week 7
- Lecture 35: Deriving the full force extension curve
- Lecture 36: Random walk models for proteins
- Lecture 37: Hydrophobic polar protein model
- Lecture 38: Diffusion in crowded environments
- Lecture 39: Depletion interactions
- Lecture 40: Examples & implications of depletion interactions
Week 8
- Lecture 41: Introduction to Biological dynamics
- Lecture 42: Introduction to rate equations
- Lecture 43: Separation of timescales in enzyme kinetics
- Lecture 44: Structure and treadmilling of actins and microtubules
- Lecture 45: Average length of polymers in equilibrium
- Lecture 46: Growth rate of polymers
Week 9
- Lecture 47: Dynamic treadmilling in microtubules
- Lecture 48: Introduction to molecular motors
- Lecture 49: Force generation by molecular motors
- Lecture 50: Models of motor motion
Week 10
- Lecture 51: molecular motors
- Lecture 52: Free energies of motor for stepping
- Lecture 53: Two state models
- Lecture 54: cooperative transport of cargo
Week 11
- Lecture 55: Cytoskeleton as a motor
- Lecture 56: translocation ratchet
- Lecture 57: Spatial pattern in biology
- Lecture 58: Some common spatial patterns in biology
Study Material
- Lecture 59: reaction diffusion and spatial pattern
- Lecture 60: Pattern formation in reaction diffusion system with stability
- Lecture 61: Condition for destablization in pattern formation
- Lecture 62: Schnakenberg kinetics
Live Session
Syllabus and materials
At NPTEL, as the course publishes them.
Credits and licence
- Institution
- IIT Bombay
- Department
- Physics
- Teacher
- Prof. Mithun Mitra
- Level
- Undergraduate
- Language
- English
- Subjects
- Physics
- Source
- NPTEL
- Licence
- CC BY-NC-SA, as NPTEL states it. Non-commercial use only. NPTEL's terms
- Attribution
- NPTEL states: "Distributed under Creative Commons Attribution-ShareAlike / CC BY - NC - SA", beside a BY-NC-SA badge.
- Who can watch
- NPTEL gives no rating. Invisible Network shows it to Tweens profiles and older, judged from what the source says about it. How courses are placed
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