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12.6: Integergenic Non-coding RNAs- missing lincs in Stem/Cancer cells?

Computational Biology - Genomes, Networks, and Evolution · LibreTexts

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    From LibreTexts, under CC BY-NC-SA 4.0, as the source states it; its equations are written in TeX, which the PDF shows typeset. This page at LibreTexts.

    example: XIST

    XIST was one of the first lincRNAs to be characterized. It is directly involved in deactivation of one of the female X chromosomes during embryonic development. It has been described as having the ability to ”crumple an entire chromosome”. This is important because deactivation prevents lethal overexpression of genes found on the X chromosome.

    RNA is important for getting polychrome complex to chromosome ncRNAs can activate downstream genes in Cis, opposite in trans; Xist does the same thing.

    This page titled 12.6: Integergenic Non-coding RNAs- missing lincs in Stem/Cancer cells? was last modified on Wed, 17 Mar 2021 20:40:41 GMT and is shared under a CC BY-NC-SA 4.0 license and was authored, remixed, and/or curated by Manolis Kellis et al. (MIT OpenCourseWare) via source content that was edited to the style and standards of the LibreTexts platform.