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23.5: Further Reading, Tools and Techniques, Bibliography

Computational Biology - Genomes, Networks, and Evolution · LibreTexts

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    • Becker, S. A. and B. O. Palsson (1908). Context-Specific Metabolic Networks Are Consistent with Experiments. PLoS Computational Biology 4(5): e1000082.

      – If gene expression lower than some threshold, turn the gene off in the model.

    • Shlomi, T., M. N. Cabili, et al. (1908). Network-based prediction of human tissue-specific metabolism.

    Nat Biotech 26(9): 1003-1010.

    - Nested optimization problem.

    - First, standard FBA

    - Second, maximize the number of enzymes whose predicted flux activity is consistent with their measured expression level

    23.5: Further Reading, Tools and Techniques, Bibliography is shared under a not declared license and was authored, remixed, and/or curated by LibreTexts.