9.4: Assumptions for Computational Gene Identification

Computational Biology - Genomes, Networks, and Evolution · LibreTexts

0%

Contents

    Text

    Size
    100%
    Theme
    Typeface
    Line length
    Spacing

    From LibreTexts, under CC BY-NC-SA 4.0, as the source states it; its equations are written in TeX, which the PDF shows typeset. This page at LibreTexts.

    The general assumptions for computational gene identification are that exons are delineated by a sequence AG at the start of the exon and a sequence of GT at the end of the exon. For protein-coding genes, the start codon (ATG) and the end codons (TAA, TGA, TAG) delineate the open reading frame. (Most of these ideas can be seen in Figure 9.3) These assumptions will be incorporated into more complex HMMs described below.

    page185image51878608.png
    © source unknown. All rights reserved. This content is excluded from our Creative Commons license. For more information, see http://ocw.mit.edu/help/faq-fair-use/.

    Figure 9.3: Delineation of Exons and Open Reading Frames

    This page titled 9.4: Assumptions for Computational Gene Identification was last modified on Sun, 03 Jan 2021 23:16:14 GMT and is shared under a CC BY-NC-SA 4.0 license and was authored, remixed, and/or curated by Manolis Kellis et al. (MIT OpenCourseWare) via source content that was edited to the style and standards of the LibreTexts platform.