5.3: Activity 2

Integrated Human Anatomy and Physiology Lab Manual II: Neural and Cardiopulmonary Systems · LibreTexts

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    WBC Morphology - Image-Based Identification

    Objective

    Build skill in recognizing white blood cell types by their visual (photomicrographs) features, then use that skill to make and interpret a basic WBC differential. This skill is central to understanding immune responses and diagnosing many blood disorders. You'll see how distinct nuclear shapes, cytoplasmic colors, and the presence or absence of granules help distinguish each cell type (neutrophils, lymphocytes, monocytes, eosinophils, and basophils) using feature-based criteria. Modern techniques, including both manual examination and machine-learning tools, enhance accuracy and speed in WBC identification.

    Instructions

    Examine instructor-provided images (Figure \(\PageIndex{1}\)) of stained peripheral blood smears; identify WBCs using defined morphological cues; justify each ID with at least two distinctive features.

    Collage of blood cells: eosinophil, basophil, lymphocyte, monocyte, and two neutrophils.
    Figure \(\PageIndex{1}\): Labeled microscopic images of blood cells showing granules, lobed nuclei, and staining differences for identification. (CC BY-SA 4.0; via Lecocyte).

    Figure \(\PageIndex{1}\) displays five microscopic images of blood formed elements labeled by numbers. Each image highlights different white blood cell types. 

    Table \(\PageIndex{1}\): Identification of white blood cells with at least two distinctive features per cell.
    Number White Blood Cell Identified At least two distinctive features supporting identification
         
         
         
         
         

    This page titled 5.3: Activity 2 was last modified on Fri, 27 Mar 2026 18:05:35 GMT and is shared under a CC BY 4.0 license and was authored, remixed, and/or curated by Lakshmikanta Sengupta and Susmita Sengupta.