# 135: Bipolar and Depression

An episode of [Physician Assistant Exam Review](https://invisiblenetwork.ai/podcast/505246808), 19 Aug 2025, 43 min.

Audio: https://traffic.libsyn.com/physicianassistantexamreview/135.mp3

Bipolar and Related Disorders Chronic mood disorder with episodes of mania/hypomania and depression.Onset typically late teens–20s. Equal in men/women. Strong genetic predisposition. Clinical Presentation Bipolar I Disorder Bipolar II Disorder Cyclothymic Disorder Hallmark exam clues Labs, Studies, and Physical Exam Findings Treatment First-line (mood stabilizers): Adjunctive / Antipsychotics: Antidepressants: Non-pharmacologic: Key Differentiators Bipolar I vs. \[…\] The post 135: Bipolar and Depression appeared first on Physician Assistant Exam Review.

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