# FMD – Fasten neu gedacht mit Prof. Valter Longo & Nina Ruge

An episode of [staYoung - Der Longevity-Podcast](https://invisiblenetwork.ai/podcast/1729988637), 30 May 2025, 54 min.

Audio: https://traffic.megaphone.fm/APO5614174376.mp3

Heute spreche ich mit Prof. Valter Longo, einem der weltweit führenden Experten für gesundes Altern und Ernährung. Bekannt wurde er durch die Entwicklung der Fasten-mimicking-Diät (FMD) – einer pflanzenbasierten 5-Tage-Ernährungsform, die die positiven Effekte des Fastens erzielt, ohne komplett auf Nahrung zu verzichten. Gemeinsam tauchen wir ein in die wissenschaftlichen Hintergründe, die beeindruckenden Ergebnisse klinischer Studien und die Frage: Wie können wir durch gezielte Ernährung länger gesund leben? In dieser Folge sprechen wir u.a. über folgende Themen: • Kann eine 5-tägige pflanzenbasierte Diät dieselben Vorteile wie klassisches Wasserfasten bringen? • Wie konnte die FMD in Studien Diabetes, Bluthochdruck und biologische Alterung positiv beeinflussen? • Wie hilft die FMD dem Körper, Fett abzubauen und gleichzeitig Muskelmasse zu erhalten? • Kann FMD beschädigte Organe wie Niere oder Bauchspeicheldrüse regenerieren? • Warum ist Wasserfasten für viele Patient:innen ungeeignet? • Welche Prozesse wie Autophagie und Ketose werden durch FMD aktiviert? • Welche Rolle spielt FMD in der Krebstherapie? • Wie beeinflussen reduzierte Aminosäuren Wachstumssignale wie IGF-1 und mTOR? • Wird es in Zukunft personalisierte FMD-Programme für bestimmte Krankheiten geben? • Warum lässt sich FMD sicher zu Hause durchführen? • Könnte FMD eine echte Alternative zu Medikamenten werden? Weitere Informationen zu Prof. Valter Longo findest du hier: https://valterlongo.com/ Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder YouTube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an deinen Arzt/deine Ärztin. STY-189

## Transcript

[0:04] Welcome to stay young today or would like to shine a new light
[0:08] on ange and topic of longjetity fasting.
[0:12] We know a lot about the effects of fasting on i wassels that it
[0:16] can't prevent age related diseases and biologicaly
[0:19] regerminators. And I'm extremely please to
[0:22] welcome a leading international expert in age research here
[0:26] today at stay young. He is the nutrition expert par
[0:30] excellence who has a chiefed worldwide fame with the
[0:34] development of the fasting mimicin diät fmd for short a
[0:40] diad that is set to have exactly the same positive effects as
[0:44] strict waterfasting and fact, fmd is set to be even more
[0:48] efficient. And also support cancer
[0:51] therapies. My guest is professor of
[0:54] Gerontology and Life Sciences and hets the Long Jevity
[0:58] Institute at the University of Southern California, Los Angeles
[1:01] is a Multible Bestselling author Professor Valta, Longo Welcome
[1:06] to stay Young thank you to have. You thank you for have me.
[1:11] We making fasting privites that a protection against age related
[1:15] diseases and has a strong, a preventive effect and classic
[1:19] forms of fasting can it really be set fmd is superior to
[1:24] fasting. Fmd is trying to move away from
[1:30] ideas like fasting, i over say fasting is kind of like eating
[1:35] or sleeping is sleeping good for you well at turns out that.
[1:40] You Mord and sevenowers is good for you, but Mord and nineowers
[1:43] is bad for you right. So so fasting is the same way i
[1:48] so we we we be in talking of a fasting for thosles of years and
[1:52] so from everything we see fasting to be good bad and
[1:56] nutron but depending and i you do it and and when you do it and
[2:00] and we do it so i think a fmd a fasting me can dide is a way to
[2:06] move away from words like fasting.
[2:08] And movin to clicker trials, you know can like the FDA standard,
[2:13] but bassane ok, maybe maybe drugs are not the only solution.
[2:18] Maybe we can have you know plan based nutritional intervention
[2:24] that can have the buddy repair it self, but we need to have the
[2:29] same standard as the FDA as set up for drugs or the wise we just
[2:34] can have drugs or ideas like fastic.
[2:37] And so yes, so the fmd's about that right, so you know so for
[2:42] example in Germany or the Heidelberg University testet the
[2:47] fmd and the i beaters pates it's right and they'd it's six cycles
[2:51] one's a mount and shot and it's the find is of of the fast to me
[2:56] can did am mount against fided is of a midterenian did in a
[3:01] midterenian did it absolute re nothing to die i beaters pates
[3:05] but the. But the fasting meaking that
[3:08] regressed IA beatles in but a seven personal patient also
[3:11] reduce i pertention in seven personal patient, so yeah, so
[3:15] that's the kind of in that's a german example from euron
[3:18] University seanin the way we should do it otherwise fasting
[3:25] remain sonting for the few right one in a hund a mabine germany
[3:28] of you a fumor, but it i's like a small nish.
[3:33] But that's talk about fasting because we have to compare fmd
[3:37] with the water fasting or the classical fasting.
[3:40] I guess we that's talk about the main effects of fasting what it
[3:47] be possible to explained prefly the gently inhibiting of cell
[3:53] division, for example, or the activation of atophogy or the
[3:59] catosis. Which is also triggered by a
[4:02] classical, fasting and fmd? I will like to comparit later of
[4:09] usly does the. Same ok so the same that the
[4:13] dick for example, what a only fasting right, so you what a
[4:16] only fasting if you do it for a sate n r's, they just the give
[4:22] and example i we can not no longger used what's like fast if
[4:26] you do at 18 r's they you're going to a lot of benefits
[4:28] right. And then it turns out that ftur
[4:31] years that eighty nowers it for in valeskeeping breakfast is
[4:35] going to is as so see it we the short and liesband and more
[4:38] cardivasqual dc so then you can look a sixty nowers and eighty
[4:42] nowers or daily sasting and say and it's very good for me and i
[4:46] was say no it's not right because eventually it's as so
[4:50] see it at we the short that liesband and more cardivasqual
[4:53] dc so, so yes, so then. It's ok me know you aske me what
[5:00] that's what or on the fast in us, we'll you know ftr, ftr
[5:04] somniires and a say a cupledays you see the keat on buddy's go
[5:07] up ftr mb forfightdays you see that I've all for you been
[5:11] activate in som sells, but that's he relevant right because
[5:16] if he ventory that's more damage, then good then that's
[5:20] just a short on benefits i give in example.
[5:23] If you in Jack, there's have we'n insulent when to disco with
[5:26] insulent and fifty years, go insulent that's a lot of good
[5:30] things right for you, but eventory insulent you know call
[5:36] as is instulent resistance right so just because you see a short
[5:39] them effekt with you's out ofogy or it's anything you one, it's
[5:42] he relevant right because you want to see what that that to a
[5:47] person lie spam and not it example smoking right smoking.
[5:51] Just to make people loose wate i like Nico team mikes people
[5:55] loose wate, but i don't think but you will reckoman the smokin
[5:58] as a way to you're a liestal to improve your your healt right so
[6:05] i think fastin is in the same domain i can do a lot of good
[6:09] temporally, but then a lot of damage that's what we have to
[6:12] move a way from from fastin aspecially what a only fastin
[6:16] because it's. I poklassemia in a lot of people
[6:19] can calls i pok tension in lot of people and a movie in to one
[6:24] are the tible fast and langed that is bing klinically tested
[6:28] and lonter not a shurter is showing you know effects right
[6:33] so yeah, so I'd also gs happens up to five days you know kito
[6:37] kito genas is apptor f'akuple days, but then i've going to not
[6:42] example if you do fast for longin off.
[6:44] You enter that's a water on the fasting if you do that for
[6:47] longin up you lander a hyper metabolic state, it's go law
[6:52] energy expenditor mod and now you can be like in that law
[6:57] energy, so you basically consum last energy and that's not what
[7:01] you want i so you don't want to enter the state he will Deutz
[7:04] very effektive if you enter the state.
[7:06] Then it's going to be diffical for that person to montane low
[7:09] wate, and this is why you see if you do.
[7:11] That's a lonetown what or only fasting you loose wate and then
[7:14] you regane the wate, but and that's a worsting you can you
[7:18] can. Do that's really revolutionary.
[7:20] I just all the klinic see are in Germany or it's a land oalstria
[7:26] the fasting klinics they have no in total depression because that
[7:30] business is is faiting a way. When this is right, so you say
[7:39] the fasting effects, we a chief of the five days ok, but this
[7:45] effects you don't one to have so tell me.
[7:50] You don't know I'm not sing that I'm sing that.
[7:54] You know just because you get in the fact like they that you do
[7:57] tendays of what on the fast and and you have benefits on blood
[8:01] pressure. You have benefits on.
[8:03] Wait it's you relevant if you then regen it and we know now
[8:08] from epidemiological they that if you do this your multiple
[8:11] times it can short and your life right a lot i'm as bettered to
[8:15] not loser all that to losered regain it loser regin so what
[8:19] you want is santing that is they safe that you can do.
[8:24] That make you the gain a benefit and mantan it right.
[8:28] That's what you want and so I'm sand that can not we can no long
[8:33] go use word like fasting or what a only fasting yeah main you can
[8:37] also do it we what a only fasting sure but you know extly
[8:41] all many days all frequentity so that depation you know gains
[8:46] that benefit that's not you don't identure the patient with
[8:50] i potention i po glassemia xed accept as fasuity because we can
[8:54] we can not just do it in clinics you know we have to do it if
[8:58] this is going to have the planet you think to have it so have a
[9:02] but it can with a home right, so that's you going to reach a lot
[9:05] of people, it's so you do it a home, i do do it so you don't
[9:10] have you know you don't have sideefax you don't have i
[9:13] potential I've can glassemia lot you don't have a hungar right
[9:16] because if you hungar all the time you're not going to do it.
[9:19] So that's we'll do's are all the things when you can think but
[9:22] and you can not just go down and backup what have it is i know
[9:26] black pressure colestoral it's a matter it's get a comed down and
[9:31] stay down right that's a mission it's he relative i you know i
[9:34] don't know you there's papers shine that right if it can's
[9:37] down and go backup it can be was and not do in it it all.
[9:42] So now we have to talk about your fast and mimicing diad and
[9:46] i am in favor of journalistic transparency.
[9:48] You founded the company al nutra in 2009 al nutra a means
[9:53] longivity through nutrition that you receive no profits from it
[9:57] because the contracts tipulates that all of it goes to your
[10:01] foundation, so your team is developing fmd products there,
[10:07] let's take a close a look at the products pro alone.
[10:11] What does the fmd? This is a five day package?
[10:15] What does it contane and what's the effect?
[10:22] So the fcores the curities and was ok long go now a pushes,
[10:25] it's on diad the so you know from the beginning and so ok,
[10:30] that's do it so i don't like animon and so it was really
[10:35] import i and by the way. The problem if you do this is
[10:39] what we don't like people do an fmd you know one somond on last
[10:45] they have to but so the problem you can also be fmd, that's not
[10:48] to be just what a only fasty you can with the fasty me and that
[10:51] is a do tree fmd consecutive we don't like that i don't like
[10:55] that all i don't want people to do you know fmd fidedays and i
[10:59] don't not a fidays and fiday i you're just say like we just
[11:02] finish the kind of a tral. In in sodanitaly it's once of
[11:06] retry mons rate once of retry mons to do the fight they fmd so
[11:10] what is it, it's a localary lot shougar a lobroath and hifat
[11:16] plan based diad and so it's combining so we so we're
[11:21] molacure biologies Genesis geneticis and so you know when
[11:25] you here's a go we we do the what fifteen years a go, we do
[11:29] the first clinical trial at in Los Angeles A USC Nordic Nordics
[11:33] Center. I'm what are on the fasting in
[11:36] cancer patient right. So we are schon in animal
[11:38] studies that what are on the fasting was make in the mouse,
[11:43] more protective and the cancer sos more sensitive to kimo that
[11:47] right so that we the lunch the first klinicotrol and and we
[11:52] we're very surprise when patients that now one of the
[11:54] word on the fast right we we do of for sure the very motivate
[11:59] and the oncologist are very motivate, it's going to it's
[12:02] going to work. And but no going to do, but
[12:05] that's when we then when back to the national institut of held
[12:08] and they're can that to do a fasting mimic in diat so ok
[12:12] that's the patient eat and in the same time get the benefits
[12:16] of fasting and so we are experts in connecting ingredians in the
[12:21] diat with cellular fasting respons so was just a metal of
[12:26] trick in the the cell and the system.
[12:28] In to have in ingredious that don't interfear with the fast
[12:32] and respons right, but antapo that i make the decision that II
[12:37] wanna to be ingredians that we're also see that will learn
[12:40] jevity and and you know very long lights right, so it's busy
[12:45] the combining the long jevity diats or the world what i call
[12:48] the long jevity diat with the fast and Mick in diat i so it's
[12:51] a very healty, so the vaged of ball that not.
[12:54] The you know ingredians that are that are plan based and there
[12:59] are and there are also have the property so they're going to
[13:05] feed with the fasting me fance. So, the crusal thing is that or
[13:10] bodyself do not sands any nutrians with is diad even
[13:14] through the body receives between one thousand, one
[13:17] hundred and 1 hundred calaries today, we do this foods remain
[13:22] on the the radar of nutrian detection.
[13:25] Yes because for example, fats and certa fats are part of the
[13:30] fasting respons right. So, so the Buddy if there are
[13:33] fats do's and really register as a name, toy fasting and respons
[13:38] ingreed I'd so i continu is out, but because normaly we have
[13:43] resers most people have copal mons of fat resers and so that
[13:47] fat because are feel for mons and so if you e fat or you have
[13:52] your internal fat and that's ok that that that's an register as
[13:56] an interfirens with the fasting now sugans prolotins a specialy
[14:01] soton and. As is the higher levels as
[14:03] certum point, that's going to black the fasting respons right.
[14:07] So so that's like we charter do we have ingredians that you know
[14:11] like glisseral insider the fasting to in that glisteral
[14:14] it's part to the fasting the break down of fats and so again
[14:18] the buddy do's a mine but the buddy da can used glisteral to
[14:23] make sugar when in needer i so it's if a patient is going in to
[14:28] a very log like simic level. Now that glisseral that we can a
[14:31] lot of them to make rapidly glucos so that the brain now can
[14:36] be feeled right. This is.
[14:37] This is part of the tricks that we used to you know respekt to
[14:41] fast and respons and get protectipations from problems
[14:45] and i lot of one we see in animal data, it's what are
[14:48] really fast and actually calls in christlicage of the got right
[14:52] or the mies but a fast and mick in died this not i so that the
[14:56] fast and mick in died a sim to. Give the order to the got don't
[15:00] break down to match because there's still food coming to you
[15:04] and also there is a isu of energy expenditor that they
[15:08] justion. Is calls in a lot of anderg
[15:10] expenditor with you don't have we the fastin that is notin to
[15:14] they just i we're only fastin notin in they just we the fastin
[15:17] we can i it the but i still have in to do the word to they just
[15:20] it's keep in the in the investin relative in tax, so there's no
[15:24] liquid and we know it's it's also we seen callsin stampsell
[15:29] active schon testin a stampsell active schon, and so it's a
[15:32] loting to do all the things the we're only fastin us but and
[15:36] remue so the problem that's so see it we're we're on the fast.
[15:39] But i got one package and i taste it and i did the diad and
[15:44] II faud there is not much fibor in and fibor is they're
[15:50] important for keeping your got working.
[15:53] I mean the fmd is a compromise. I so we you don't wann a fmd is
[16:00] a medicine essential, it's not been tested in fortifight klinic
[16:04] or trials. In Mostally Independant
[16:06] University we at the companies not in to do we that you know
[16:09] we'd'll berg, for example, did it songs to the media song
[16:13] conclusion no interfinance von the company right, so the fiber
[16:16] is sonting that be longs for the diat every they're so that rest
[16:20] of the year you can have all the fiber in the world in that fides
[16:23] you want to have the fmd exectory as the scrib right.
[16:28] And there is all a lot of reasons right.
[16:31] For example, we have a relatively hi start content what
[16:35] we train of fight me are you as me a but the kito genesis we're
[16:40] ash i design that so that the kiton buddy level we'll not be
[16:44] to hi right, so i do now one hi kiton buddy that level what for
[16:49] the long is time people talk about kiton buddies fiding
[16:51] cancer but kiton but for serton cancers kiton buddies help the
[16:55] cancer grump. So you know i do now one this
[16:59] yoyo of high kitum buddies and lo kitum buds and this is one of
[17:03] the reason why this and off startes in the emix a easer for
[17:06] the patient because people like you know starts like rise flow,
[17:10] we're what have and but it also a keeps a lot of the kitum
[17:14] buddies to go up but not to hi right to don't go up and i'll
[17:18] stay up and they can down versus water only fasty you have the
[17:22] kitum bud is go very hide right, but.
[17:25] But yeah to somebody that is pretis boss that i've really
[17:27] hike it on buddies cool mean some cancer so's actually grined
[17:32] more rapidy. Ok so to understand how fmd
[17:37] works and ho practicaly i us it first.
[17:40] How does it work to understand it pretty much better the
[17:44] crusial thing is the protein content because it is amino
[17:49] assets that's bitch on amtor and anabolic processes.
[17:54] If so i Mino Assis you have low, I Mino Low.
[17:58] I Mino assis that are aktivate in grotor Mont I GF One Tor rass
[18:04] x at so I've low i mino assis and then you have low trugers
[18:07] and low insolent right so you have low graltspectors low
[18:12] truger and the low truger low insolent to get that we the low
[18:16] igf one low tor, das is that's what you want you know if you go
[18:21] back to. There's in just that we were the
[18:23] first to in are show that we can make an organizm live tentines
[18:28] longger right the simple loganizm by blackin the sugar
[18:31] patway and blackin the prolotane patway right.
[18:36] But if we black for the mutations that black the sugar
[18:39] patway and the protan patway the he's live five times longer, but
[18:43] he free fasted them now that lee ten times longer so, so there's
[18:47] still all the patways that a clane roll that we don't quite
[18:51] on the stand yet, but yeah so the maximone was Black in the
[18:55] sugar patway Black in the amino asic patway and then an tapo
[18:58] that fastin and because fasin at eve more them then we's.
[19:03] So loke Protein. Low glue coast what is in you
[19:08] get a bar for breakfast you get a sub and some olive oil you get
[19:13] some olives you get for the first days and crackers so what
[19:18] is in and how long to to take your team to develop of this
[19:24] very specialized composition. It to goods they nicht so one me
[19:29] be five years right lot of work in myes, but then i lot of
[19:33] thinking right of a. Patients and walk of this to the
[19:36] page. What does it do the black press
[19:38] or what does it do to the Hypo glassemia Excel, Excel right
[19:43] what on the responsor patient is they're like any uncomfortable
[19:47] in offside effects right so so it then you i think it to go
[19:51] what ten years to devel of the basic fmd, but then we when in
[19:57] to alzimer autoimunity so it one as i can.
[20:02] The cancer is a completely different fmd from automunity
[20:07] fmd from the alsimer fmd so different caleries different
[20:11] ingredians so each for each us, we so now stand for the
[20:16] university of miami are about to publis two papers and fmd in
[20:20] automunities and so do's are now with developing for the fmd,
[20:27] they're a gonna be spezialies. For people with of a right you
[20:31] about to mirities. So Let's talk about pro land,
[20:34] this is for off for everybody for prevention.
[20:38] So 5 days package every three mouth to keep your healthy and
[20:43] to support your healthy long jevity please explain to me what
[20:48] all the responses. In my body in mysels when i take
[20:52] this five days diad for me. So what fossible the in the
[20:57] clinical trials, we've song that aneverage people have to three
[21:02] cycles the fmd der biologicalage was we do's by about two and a
[21:05] half years so they at the markers of people there are two
[21:10] and a half years younger, i then the posibilities like we'll what
[21:14] you do that three for times to year for twenty years, we don't
[21:17] know but so to the. The projektions we're a big
[21:20] difference in a biologicalage in a big difference in a like
[21:24] expectance it, but then what a have as mechanistity and we
[21:28] think that a multiple things that have a one is a
[21:32] metabolicary programm, so for example, and this is very clear
[21:36] on i for different klink a traus inkluding the one that evention
[21:39] for for heidelberg, the patients that have diabedes or p
[21:44] diabedes. The the fmd is just a right
[21:48] level in time five days to beginn to revers and revers
[21:52] insulent resistance right, so metabolity they start a lousin
[21:56] up dominal visual fat, but they don't louselin Buddy Mans right,
[21:59] so is a metabolic reprogramming now if you like at GLP, You one
[22:04] Drugs, They can't wait los big wait loss, but the alsocos a lot
[22:10] of that wait los is massalos and potentialy bone loss right.
[22:13] We the fmd because it's a natural is just triggering
[22:16] you're on something that is all was be in part of are passed,
[22:20] but it's not in a very prise maner we do not see and now it's
[22:23] trial number for five no no limbody mass lost that is a
[22:27] temporate limbody mass lost so a massa lost, but then you regain
[22:30] and as soon as you go back to the normal that right so that is
[22:33] no long term limbody mass lost, so that's metabolic we see and
[22:36] we're standing to see in conicutral it stemp salutive
[22:41] bitch right, so we start a seen. In and we are demonstrative is
[22:45] of it and years a go in mys so we're the bomero stempse so
[22:49] what's call long term and i'm not to for you to stempse they
[22:53] when way up and then this themsells give rise to a
[22:58] rejuvenate immunsystem. For example, i so that we're
[23:02] standing to see impatiens, for example, we just publish a paper
[23:06] and kidney this is patiens and universal rom and and we so a
[23:11] tripling of this. Circulate in kidney progenit of
[23:14] sales, there's a sales that are of stamsell like so that they
[23:18] can generate the last so different sales right and they
[23:21] and there's sales that can vpr problems and the impotentialy
[23:25] contribute rejuvenish that turting and prouding the most
[23:28] import and that we's we just publish for mies and rats, it's
[23:34] in very difficult to demostate in people, but we think the same
[23:37] is happening. As what's Call Cellular
[23:39] reprogramm right, so now that is that despectors that when turn
[23:43] down they can make a all sell young gegen, and they can make a
[23:46] all to two young gegen it's so we see that the fast and we can
[23:50] die it in my some rats is so, for example, if you like a the
[23:54] rats or the pankrist we do sevure damage to the pankrist of
[23:58] a maus all to the kind of a rats and then the the rk texture of
[24:04] this organs is computity to struck it, but it's.
[24:08] Perminator there was that the festimic in the die cycles and
[24:13] you see that the the architecture of the of this
[24:16] organs goes back to norm they the somas as if the no execually
[24:22] what to do, but they you're a one of the fes of the festimic
[24:27] in die it is to aktivate stampsells and we've schon this
[24:32] to happen it in the bomero and or the stampsell that are
[24:36] releasing to the circulation. And they can give rise to
[24:41] improved or rejuvenate immunsystem and now in in a
[24:47] smalltal that we do the universal Rom that's appience in
[24:51] in Italy, we schon the impatient we kidney is, is we so a
[24:56] tripeling of the circulate in progenit of sell kidney progenit
[25:01] or sells now we don't know what the roll of the sells is in
[25:06] people. But we do not that this patient
[25:09] that have kind of this is the improve and the improvement have
[25:16] so i your was still there in most of the pate right so that
[25:19] the tree cycle there from the then they stop and then they you
[25:23] know i your later the clinitions went and measure that the
[25:28] improvement and there was still there i so sujesting the mabit
[25:31] is regenerate in rejuvenate in effekts or also curing in in
[25:36] people and. And you and then tured is what
[25:40] we call what it's called seller reprogramm you and now they this
[25:44] is supply they have a sting in the agent feel is bellmontal app
[25:49] have down this for in a forceful right they have the spectors
[25:54] called yaman archafectors and they fossily a aktivate in this
[26:00] reprogramms sells, and we jumin a sells, but this also call is a
[26:04] lot of problem right so. I now we're going to the fast
[26:07] and me can the it's active in in some of the same saldular
[26:10] factors. This rejuvenateing factors and
[26:14] but it does it in a very cordinate away so that you know
[26:19] i was sained that we we toke AI mice and and damage the the
[26:25] pankrist or to grats and damage the kidney and and the
[26:30] architecture of the pankrist. And or the kidney have to we
[26:34] give in this toxens is going to disrupted then and this is
[26:37] perman that we start the fmd cycles that fast to meing in
[26:41] this i go and you see that the for example that pankers to the
[26:45] mice go's back to making instal and so, and in this
[26:50] yamanakufactors of turn down in a very coordinated with sanding
[26:54] for the kidney, the kidney me at sunding go in collaboration, we
[26:58] Lore Perrin it's child in as off for Los Angeles.
[27:01] We at sonic of special transcip tonics so we can see the the
[27:05] architecture that three dimension all like way and we
[27:09] agos from complete to disruped to bad to what a was befor we
[27:15] tree to the the kinnee we the toxens like it's so and this
[27:18] matches also that is they every result with the we the kinnee
[27:23] demage patient if so i think that that.
[27:27] You know metabolic reprogramming them's all activation so a
[27:30] reprogramming they're all going on in patients I'll know it's is
[27:35] your to demostate and much is your to demostate is in animal
[27:40] studies, then it is to demostate in people.
[27:43] It's a lot like like americal in people's, they only buy
[27:47] nutrition so they I'm sure they know what is really precisely to
[27:52] know what is in this package for 5 days.
[27:56] There is herbelty there is olive oil, there are olives and there
[28:01] is a dright sub. There are every day to types of
[28:06] sub, but what's what's in you don't get me the answer.
[28:11] We know i don't like you know i know I can't like up the book
[28:16] and all the paper it is the scrive in detail right back, but
[28:20] it's a lot of it is sixty component right, so it we think
[28:24] me an now we're to we'll see that is sin it, but the point is
[28:28] that is been klinicaly tested in mais pricklinicaly tested in
[28:32] mais in hundred of studies klinicaly tested in forty
[28:35] klinical tralsor so. And in a words for sertant
[28:39] things right and and a words for people that don't have any
[28:42] disease and you know make them apparentity younger and in a
[28:46] more funktional and we see reduction in collestal reduction
[28:50] in black pressure, reductoring gleisemia and and i know a words
[28:53] and people we diabedes we're diabedes.
[28:57] Now it you know early datas as so just that works with people,
[29:00] we'll kidney disies and will see the autounity data coming out
[29:04] very soon from two differ in America universities, but it's a
[29:09] lobrot in Lord trugger hi fat plan based localary diate it a
[29:14] providing aid a hundred to eleven hundred calories and it's
[29:19] got sixty different componits in it so each one.
[29:23] I think study to mcsure that it's see the for people to do
[29:26] it. They can be down a home, they
[29:28] can be down safly and now proly of a 1000000 people at down the
[29:32] fmd and that's gut right that's gut because as passion the
[29:36] unastates andy sideefax as to be report it to the fda so that can
[29:40] like medicine right so so I'm think in happens, it's in so
[29:43] buty then that's to be report it so when you have a 1000000
[29:46] people that i think you're starting to get that kind the
[29:50] numbers that that you want you know as bring.
[29:52] Abalible for ten years, so it so II think that that's proly
[29:57] master what people need to know i get in expedy in expensive, i
[30:02] don't like a penny out of it, i don't get the sales of the of
[30:05] the products so II think it's it's proly the wait to wait the
[30:09] go i have a people one out tried a make it a home, i just don't
[30:13] recomand of for multiple reasons, but i can see people
[30:16] sain all you that's on a command of it is a product to by you've
[30:19] find i'm it that's what's what a people one a think ok, we do it.
[30:25] So hier in Switzerland. This 5 days package costs one
[30:30] hundred 99 swiss franks from people say okay for 5 days okay
[30:37] one hundred 99 ist the cost of research included in the
[30:41] calculation. I we in the cost of research.
[30:44] All nutra that's a little reserch right, the university's
[30:48] do a reserch Heidelberg gladian Rom my University in Los Angeles
[30:54] and a lot of it is beam funded by governance is beam funded by
[30:58] foundation that's beam funded by people that are sane you know we
[31:02] one an alternative to the GLP One Rezept or agonist we one an
[31:06] alternative the statins we one we one sunding that is a
[31:09] medicine it coms in a box. Is problem proscriber by the
[31:13] Doctor. We have that now in the
[31:15] unitestates that is fifteen 1000 doctors that recoment the fm ds.
[31:20] Ja, so i think that's a way to do it and. 15000 doctors.
[31:25] Fmd you i think is oning the unitestates of a fifteen 1000
[31:30] doctors that a register to a recoment prolon ja, so i think
[31:34] that that's to eventory that's a way you know that's for people
[31:38] that have a disease people that don't have a disease, they can
[31:40] just call. When recritionist or just all to
[31:44] the company, a ditition right, but i be in bushion the company
[31:49] to to have professionals they can help people not just to the
[31:53] product for get back to full help right, so we one so we
[31:58] follow you see that work in Germany and in halland, you know
[32:03] the patient with i videos regress, but i think in in
[32:07] Germany. With in Six mont's sixteen
[32:10] Prozent, we're really diabetes free.
[32:12] That's what you want you one seventy every prozent to go back
[32:15] to be a fee of diabetes be healty, but the the ölting but
[32:20] in germany and in holland no only diabetes was regress and
[32:24] revers but hypertential we's there is an a lot of the people
[32:28] we die pertential reducing drugus and have in benefit in i
[32:33] pertential so yes i think. It's cost what i have, but but i
[32:38] think it's it's a specialy the think must we go will only have
[32:41] to do at two a three times a here, i will say the good
[32:44] investment, but it's see only way that we'll going to be have
[32:49] a alternative to drugs it people think it we going to have an
[32:52] alternative to drugs by talking about eatin healty we be in
[32:56] talking about a meditarinian dive for fifty and evan in etaty
[33:00] nobody that's the metarinian diving right.
[33:02] So that's I'm on work right. We when we tell the people
[33:05] you're sued it better is just people don't like that i people
[33:09] don't not going to change a diad me an last and diad world
[33:14] medical and hellcare system is change people and i going to
[33:18] change right so we have a smart ideas and and way so the people
[33:24] don't change a like still but still have that benefit of you
[33:28] know I've right so. And i think about that we do
[33:32] that we publish this if you is a go in nature metabolism, we
[33:35] think mies and we get a my tellable dive we get a my high
[33:39] fat high shugar high colory dive and animal the the was and and
[33:45] this mies gained a lot of it bekam will Beast and they live
[33:48] very short with hical Estero high glaceemia hard hard damage,
[33:55] but them we do the same mies we the same dide and we get AM the
[33:58] fm the once a mon. And everything when back to
[34:02] norma but we'd when back to norma fat one back to norma
[34:05] glacenia one back to norma colestor one back to norma hard
[34:09] the damage one back to norma, so that's a muchmore realistic then
[34:14] telling in people ok for now on for get your diat and i can we
[34:19] tell people that we we have foundation klinics not profit
[34:21] foundation klin, so we tell people that but this not easy i
[34:25] think II. Malfred a time is he is a
[34:27] difficult to get somebody to drings for coffees a day to go
[34:31] to tri coffees a day, so now we imagine telling somebody stop
[34:34] your diat and and listent to me right in a mosbee we're not
[34:38] going to. Do that i what about re
[34:40] inbirsment by have insurances? You I'm going to know that's
[34:45] that's I'm belivable that's an happy it and that's because that
[34:48] is so my pharma sudical interest that is so much power by big
[34:53] Pharma and. And and so yeah, we have an sin
[34:56] that yeah, but i hope that you know sunan up in the you know a
[35:00] states of be reenbersment and sunan off that be you know
[35:04] reenbersment in in europe right by the government and zane.
[35:09] Ok, we provided so many fast them me and dias for propation
[35:14] that a number or problem. It's take a shot look at the
[35:19] cancer therapy, a specialy rest cancer and prostate cancer agis.
[35:24] It's very exiting it has an influence on both tumocells
[35:28] grove and the effektivness of camotherapy what do we know for
[35:34] sure today? We'll i'm in that i be is for
[35:39] they be is that's one disease, it's a we're pretty shure about
[35:42] that i this looking very stady very consistance all fmd works
[35:47] like works for blood practure. Liste in a soton population
[35:51] words for a insuener assistance diabetes bid i do for cancer you
[35:56] know you like in it a hundred different is is and a thason
[35:59] different therapy right, so it's i think for cancer you know the
[36:04] it is willy exiting i can you like at the work and National
[36:08] Cancer Institute the Milan it's really impressive theory
[36:11] studies, but the bro and vernity troning for example wayman we
[36:16] triple negative brass cancer. In elisine and small study
[36:20] surriving all lost wise is on if they we're an an a fastiming in
[36:24] die plus. Kimo versus kimo therapy along,
[36:27] but that's are really it's still small studies we need to see
[36:31] that you know the five on your people study, it's so just for
[36:36] can's that think's a on time, so we'll we're be in sane is the
[36:38] falling if you're really stage concepation you know fasting me
[36:44] meing in die. You know maybe Whiskey right you
[36:47] know, we don't know we we just don't know i can't have you
[36:49] tramendasly and and maybe not have you at all right so but is
[36:56] you get to metastatic breast cancer or frostate cancer or
[37:00] last of the frame cancers it's you get the van stage stage
[37:03] three stage for then we're recoment to most people paul to
[37:07] you're on cologist and as is there's sonting so busy we're
[37:11] sign. If you have a 90% chance of
[37:13] being cured by the standard therapie, don't touched don't
[37:17] changeenity, but we get patient recomendation on they have we
[37:21] they died we go to in all on jady died time ristity to eating
[37:24] so lot of recomendations, but we say don't change and don't do
[37:28] fmd, but it's the is the get to stage tree and stage for when
[37:32] the survival is much lover it special.
[37:34] If there we see the therapie and it's not working in it more you
[37:39] then we's say tal to you on call a just.
[37:42] And this see what what fmd das for example, in one of the trial
[37:46] that was publish, we're not agipations, they're a niri grup
[37:49] the onkologies and is all the same onkologies that we're i
[37:52] first present that is to them overtin years it go that we're
[37:55] really scap to go and and so now they do the trial and in they so
[38:01] that not only a teams to be working very well for all
[38:03] patiens you know in one, we're not it.
[38:06] Then they had five cases. I think they have to about
[38:08] twenty state for metastatic cans that i colorector brest
[38:13] punkuriatic and and lunk right you know the people that are
[38:19] introple big trump and this shot that i they're out of the twenty
[38:23] that we're introple five when into remission right, so there
[38:26] they the fastiming in die plus immunotherapie fastiming in die
[38:30] plus chemotherapie lot's a combination but i was be the
[38:33] fastiming in die. A many cycles of it and five of
[38:36] this one your so when in to a mission right, then they but is
[38:39] a paper sane you know the call that exception of responses in
[38:43] the cans of setting we's you know they're some before it's a
[38:47] patient, we're all this different canses going to
[38:49] remission right a from the say a stange for you know luncanser
[38:55] that's value an usual that's some but he like that in this
[38:59] patient case, for example, the patient was do in the
[39:01] immunotherapie plus fmd. And a one into remission, so
[39:06] yeah, so you know it's not conclusive we don't know and
[39:09] eating for sure, but we know that he'fure that stage and and
[39:14] the dr says a we're going out of option ok, that's they i will
[39:19] like to try the fmd and the and see what the what the uncolle is
[39:23] says and. To a developing bar protein bar
[39:28] a specialy for. Therapy camotherapy all for
[39:33] conserpations we. Just right, I'm in.
[39:35] I don't developing in the company develops II don't have
[39:42] and you know leadership position in the company, so it the
[39:45] companies developing that's the things and but in the lab i we
[39:49] in the university lab we are you know we're bringing in this
[39:53] notity technology and we're sign you know weather is an normal
[39:56] people i concepation can we. I com up we ways to get the
[40:02] benefits you entiaging effect the sedilar protection and we'd
[40:06] da corsiing provers I'm malnorisment lots a mussle messs
[40:10] cakexia yes, so that's will we specializing in trinal get all
[40:15] the benefits get bolsize of the benefit because lot of the field
[40:20] is the buting to do it. The one is a say over eat and
[40:23] I've you're can's a page, a eat is my just passible because you
[40:26] going to be wick and. And the other one, there's sane
[40:28] doned because you know a people so what it think the we start
[40:32] it. I don't it because that's going
[40:34] to kill the cancer so but you have to you know find that we a
[40:40] to eat the writing so that you get bod bened it you don't loose
[40:43] master and you're kill the can and so so and.
[40:46] We i as how do you personaly manage the amand of protein in
[40:50] your diad and vicily how do you eat?
[40:55] It so first of All you know hi animal Protein diat is a bad
[41:00] idea right and i you know we're on what certan of this and get a
[41:07] lot of people think that this is the way to go i so that is bada
[41:12] from epidemiologico studies, sentinedian studies, mouse rats
[41:16] Name it right so hi animal Protein diat is back so the good
[41:22] a mounta protein is about zeropening grams.
[41:25] A perkilogramm of but it was so if you'll right fifty kilogramms
[41:29] that's about forty grams of hi, good quality protons so i can
[41:34] not be forty grams or legums as to be forty grams of a fish plus
[41:39] seeds plus nots plus legums i you know said grams or beach
[41:44] right a category and that's a good quality if it was forty
[41:49] grams or legumes or proting not legumes so that's not when fus.
[41:54] Rotains with food, the contain prot so for the grams so protan
[41:59] from legooms i're going to be loquality so legooms a grate i
[42:05] one of the held to as food, but the protins that they're
[42:08] contained i've law levels of sotan me no as it i so you can
[42:12] have beans and you can have a chick beans and you can have a
[42:14] lot that but you have to have you know, i don't that i we're
[42:18] going to grams you need for they.
[42:21] Uni to have like a three force coming for for source as all
[42:25] that then regumes so that's that's the problem part now at
[42:29] the five this proly as to be rase to make sure that you have
[42:33] minimal leam, but the mass los minimal musal los and bondance
[42:38] if you like so that's the prod in the restorate the no is
[42:40] mosedy, we preach a pescetarian did so fish plus began with like
[42:47] the meditoranian did. Hi hi vaggibals and and law to
[42:51] normal fruit right, so not fruits in vagible but vagible
[42:56] and some fruit, but so that's an or a big change
[42:59] compredimeditoring of that and or big change.
[43:02] I think it's a personalisation right so you know and make's no
[43:06] sands for a german to be and a meditoring and that it will a
[43:09] make the sands is for the german is to be.
[43:13] What have a diad that you know has the riding greeding we call
[43:17] it the longjerity diad best on there uncesto so it's some but
[43:20] he from germany have ancestos that kind of from Norden Europe
[43:24] ok, the Vegas was at to we're slag that origin right I don't
[43:29] want to force german or no regian you now it like the
[43:33] sisilians e now they can be beneficial i'm not signed that i
[43:36] can not so a german kind it i meditoring and diaday but i
[43:40] german. You know you can have two twins
[43:43] one it's the meterinian dight and benefit chamandas and you on
[43:47] a one, it's the meterinian dight and softras like have so because
[43:51] they're alergic to tomato because they're alergic to and
[43:54] no ack blend because there you know it is a lot of reasons
[43:58] right, I'm. Meditoranian because they don't
[44:00] they just beans really what right because the the fish the
[44:04] kind's all of the maitoranian but now be the competable with
[44:07] there they justive features you know, so that's generali
[44:12] sumories is what i call the lon jevidy diad but i incer of
[44:15] people my facebook is the injer translator in german also and.
[44:20] Like gourage a people to talk to we that i've in the book of a
[44:25] profits go to the foundation. Important to know and i gets in
[44:31] that book you also menschen bad to you are a little bit like the
[44:36] people in your hometown in so them Italy personally.
[44:42] II don't like them, but i certainly you know so.
[44:48] So, the the Habits of the sentinaries I'll one of the
[44:51] fight pillars that we use to can up.
[44:54] We don't have you diad so we learn from sentinaries because
[44:57] of cours that's a grate right, we you start, we people what was
[45:00] come on at the table of a people in or kinowa will Malin da
[45:03] California so there me in as this villages, we're people if
[45:07] lom if they'd like that for a hundred and ten years and madeed
[45:11] to hunden ten years that's for to go news right to me is that
[45:13] the all. Man i be the perfate diad by
[45:17] sertenance of good diad so we start we that but then we at the
[45:20] mouse studies we at the epidemiological studies i
[45:23] studies of millions of people we like at the klinical data ja,
[45:27] we'd will roll to get that it and to.com up with the lunchery
[45:30] diad so yeah, no they II very much learn from my ansesters the
[45:36] diad and that's just mabue one ten of all we.
[45:42] Will we usedto.com up with the longerity die.
[45:45] Ja, we have to video books and we have to i get to what your
[45:52] netflix. It's not a drum is a documentory
[45:55] all with it is coming, now is I'm mine.
[45:58] You know is I'm mine is notreate, but edward norton that
[46:02] is askor winner. I think the actor and Direktor
[46:07] by Barry Alexander Multiple Time Ascor Nominated Director.
[46:11] And produzed by caratilasy ascarnomin a producer yeah, so
[46:17] it's a grateam we know they besser in my books, so I'm very
[46:22] very happy that they they think it's a it's it's going to be a
[46:26] grate way for people first of all all of it all defans go to
[46:30] the foundation from the dokumentary so to so there we
[46:34] can how people all of it the world you know, we do lot's a
[46:37] think for scholes we do festivals for childeren.
[46:40] You know we we have conserpation is so, but i can not a for that
[46:44] it get the tritman for free so that the dokumentar you know
[46:49] revenue will go to the foundation so that we can
[46:54] continue do we will we do bolt in the Unity States and a europe
[46:59] and the offaly you know will have it's on point and a funs to
[47:02] toalso.com to germany and and bring that the foundation to
[47:06] german you know it's it's it's losally metally in the US.
[47:10] So the title of the Netflix doku and state off release.
[47:15] I think Apple sevent the release and it's call fasting and the
[47:19] lon jevidia Revolution. Grate we will be really exited
[47:23] to see it. Thank you've so much.
[47:25] I get now we do understand a lot about fmd and what be very happy
[47:31] if you can't give us of you, unsers as a breeves summary at
[47:35] the end only three minutes, it's what be really really very
[47:38] outfill so what is fmd? Fmd is a plan base lobrot in
[47:45] Lostsugger hi fat Law callery die it a coms in a package.
[47:50] And and it's food is medicine and that's consum for any.
[47:54] We're from four to seven days based on the type and this is
[47:57] that we're trend a treat and and the coms with instruction that's
[48:02] what and fmd. Is fmd better of an classic
[48:05] fasting for healthy long gravity.
[48:08] This is an on a competition about beam better of words.
[48:11] I mean it's a fasting music in die it that is allowed it just
[48:17] it's a procise lang. Risize camposition it's a
[48:21] medicine that is been tested in clinical traus and i inchurage
[48:26] people to just focus not just on short term clinical traus a long
[48:32] term clinical traus, so the my question is.
[48:34] This is a been down for the fmd, so then you know for the what
[48:38] are only fasting, what are the clinical traus what are the
[48:42] sean? Of fisible they are it so I'm
[48:45] not so word about what on the fasting i start it we what on
[48:48] the fasting and I'm going to way from what on the fasting and and
[48:52] it was now my decision. It was the decision of peopal
[48:56] pations right patient refused what on the fasting uncologies
[49:00] to refus what on the fasting and that's an only dan we move the
[49:03] way from what on the fasting because mosphisition not just
[49:07] the uncologies we're word about people doing what on the fasting
[49:11] and home. And you know and evan for
[49:13] marolen experience, we we're really where it a but you know
[49:17] for example, hypotention people black pressure dropping and
[49:21] somebody and now keepy mined to us even one in a thousand.
[49:25] You know some german's can see all come on we been do in what
[49:28] on the fast and for a hunyears it's he relum right if you been
[49:33] do in it for a hunyears in a klinik right, so we'll talking
[49:36] about people do in it home and he've in one in not thousand and
[49:39] that's not the number belive in. If people do what a really fast
[49:43] and it just a metal time for the going to have problems.
[49:45] We're if that hybro gasema i potention you know and lots of
[49:49] what a right so i think frod as reason is not a competition, but
[49:53] people in to relies that there is a medical system for a reason
[49:57] that are university's hospals for a reason and everding as to
[50:01] be tested and schon to be effective and then and only then
[50:04] people to say ok i see the data, I'm convested.
[50:09] What exectly is the 5 day program fmd.
[50:13] Yeah, the 5 day program. Fmd.
[50:15] It's a bugs they contains vegritable sups a contains not
[50:21] bars, a contains sontic all giseral a contains hi fatfus
[50:26] like but a hality like allips, and so is china melt the fasting
[50:32] respons. With the one jevity ingredians
[50:35] the ingredians for the one jevity areas of the world, so
[50:38] extribility ingredians, but only the one and that mimic fasting.
[50:45] Rich Effects of fmd are scientifically proven.
[50:50] Yeah, so scientifically that is a long long list because science
[50:53] is also the science in my's clinicaly proven.
[50:56] I think now i's pretty clare that ped i beat is.
[51:00] As be in klinicaliprovan diabetes regression
[51:03] klinicaliprovan ftx biologicaliage people because in
[51:08] elis base on markers because in younger a liable younger, that's
[51:12] now klineli cli in a sean. I'm inprovan it's hard to say
[51:17] because it's in up this is opinions about a you majorum
[51:21] aging so dosa or some on the klinical provan now we're
[51:25] starting to see lots a data very consistant with colestoral
[51:29] loring. A pressure lovering and i think
[51:32] that the real interesting think is a sophistication of this
[51:36] implulements thatdont.com with little massal massalows or
[51:41] bondanceity lost so far no indication in in the grama jurg
[51:46] of the trial. I'll like the GLP One Trials, no
[51:51] indication that the benefit that associate with big citapent.
[51:56] Do you do fmd yourself and it's so how many times the.
[52:00] Year i do the fmd mebey a want or quice the year and but i also
[52:06] follow the longery did i do kind of to the eening and do twelve
[52:09] hourers one they to friday askeep lunch.
[52:12] So i do lot so things that alarmy to move it down to one
[52:16] for quicey here i exercise a regulary are wellican, i are
[52:20] they so i think the more you you get a way from what i do the
[52:24] more problem the you going on the cycles of the fmd all the
[52:28] way to diabetic patient that I'll beast have diabetes and
[52:33] they need to do it i here one six to tweltimes in a here.
[52:38] There's the one or to that i do. Professor Avalto Longo, Thank
[52:41] you from the bottom of my heart for your time and for all these
[52:46] insights. I'm really happy and i get all
[52:49] our follows will be very, very happy to listen to you and i get
[52:55] fast and mimican diag we will, we will here a lot and future
[53:00] about that thank you very much for your time, thank you.
[53:03] Thank you thank you. Danke fürs Zuhören.
[53:06] Ich hoffe diese Folge hat dir gefallen.
[53:09] Weitere Informationen findest du wie immer in den Shownotes, wenn
[53:13] du etwas in dieser Folge gelernt hast und diesen Podcast
[53:17] unterstützen möchtest, würde ich mich über eine Bewertung freuen,
[53:20] damit hilfst du mir und anderen Zuhörern, dass dieser Podcast
[53:23] und seine Inhalte leichter gefunden werden.
[53:27] Besuch mich auch auf meinen anderen Kanälen bei Instagram,
[53:31] tik tok, Facebook oder Youtube. Ich freue mich immer über
[53:36] Feedback und weitere Fragen von dir.
[53:39] Alles wird gut, aber nicht von alleine.

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