# 🔬 ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub

An episode of [Latent Space: The AI Engineer Podcast](https://invisiblenetwork.ai/podcast/1674008350), 27 May 2026, 1 h 10 min.

Audio: https://podcasts.beehiiv.com/3967c1f2-cb97-4eb0-a5c0-21a1d2579408/01a15fdf-0e93-7e1a-880d-d73752a1f915/01a15fdf-abae-7eb3-8200-4f6e3406652c/01a15fdf-ac5a-7776-9f42-0c52646df33a.mp3

Editor’s note: In our first BioHub pod with Priscilla and Mark they discussed their acquisition of EvoScale, led by Alex Rives, who is now Head of Science at BioHub. With ESM-1 they trained language models on millions of protein sequences drawn from ac... Full show notes and links

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