# Cannabis as a Powerful Medicine (ft. Jodi Duval) | SNH Podcast #68

An episode of [Health Optimization Medicine Podcast](https://invisiblenetwork.ai/podcast/1663974629), 24 Apr 2024, 24 min.

Audio: https://traffic.libsyn.com/secure/672d8edf-a640-45ce-ac61-cd5f898a7b27/SNH_68_Audio.mp3?dest-id=3824325

In this episode of the Smarter Not Harder Podcast, we explore the fascinating world of cannabis and the endocannabinoid system, shedding light on its medicinal properties and potential impact on health optimization. *Join us as we delve into:* + Understanding Cannabis: Learn about the medicinal properties of cannabis and its complex interactions with the endocannabinoid system. + Exploring Cannabinoids: Discover the diverse range of cannabinoids found in cannabis and their potential therapeutic effects. + Prescribing Cannabis: Gain insights into the challenges and strategies involved in prescribing cannabis for optimal health outcomes. + Forms of Consumption: Explore the various methods of consuming cannabis, from smoking to edibles, and their implications for health. + Misconceptions and Quality Control: Address common misconceptions surrounding cannabis and learn about the importance of quality control in cannabis products. *This episode is for you if:* - You're interested in learning about the medicinal properties of cannabis. - You want to understand how cannabis interacts with the endocannabinoid system. - You're curious about the different forms of cannabis consumption and their effects. - You're seeking clarity on common misconceptions surrounding cannabis. - You're interested in optimizing your health using cannabis in a safe and effective manner. Tune in to gain valuable insights into the world of cannabis and its potential impact on health optimization! *You can also find this episode on…* Youtube: https://youtu.be/CjbNQuQ1yk4 *Find more from Jodi Duval:* Website: https://www.revitalhealth.com.au/naturopathy/about-us/jodi-duval/ Instagram: https://www.instagram.com/jodi.duval/ *Learn more about Smarter Not Harder:* Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @homehopeorg & @troscriptions on Instagram.

## Transcript

[0:00] Jodi Duval_Cannabis for Health Optimization:
[0:00] Good morning.
[0:01] It was so lovely to see you
[0:02] or some of you last night.
[0:04] So thank you so much for coming along.
[0:06] And I hope you enjoy my accent because
[0:10] I tend to get that everywhere here.
[0:12] When I'm here, I get pulled over in the
[0:15] hallway and get asked to say car park.
[0:18] And I don't know why.
[0:22] So today, I'm talking about cannabis.
[0:24] It's quite ironic actually because
[0:26] in Australia it is still very limited
[0:29] access and that is quite the funny part.
[0:32] But I am a bit of a rebel and I do like
[0:35] finding the best things for my clients
[0:38] and today I wanted to make this a talk for
[0:41] you and make it very clinically relevant.
[0:44] Paint
[0:44] Jodi Duval_Cannabis for Health Optimization:
[0:44] a bit of a picture of how beautiful
[0:48] the cannabis plant can be and
[0:50] the enormity of how it treats.
[0:52] And also, the system within the system,
[0:55] the endocannabinoid system that we have.
[0:58] I found it so fascinating, and when Dr.
[1:00] Ted asked me to create a module,
[1:02] the advanced module for Home Hope on
[1:05] cannabis, I dived really, really deep.
[1:08] I had a fabulous time doing it.
[1:10] And this is just a small little
[1:12] snippet of what I found out.
[1:14] So let's get started.
[1:16] All right.
[1:16] Dr.
[1:17] Ethan Russo has come up with, some
[1:19] fascinating information on cannabis.
[1:22] He does say that cannabis is the
[1:23] single most versatile herbal remedy
[1:26] and the most useful plant on earth.
[1:28] Cannabis has a little bit
[1:30] of a stigma surrounding it.
[1:33] I don't know about you guys here,
[1:34] but we call cannabis smokers in
[1:36] Australia, potheads, stoners.
[1:41] It's got a really bad
[1:42] connotation linked to it.
[1:44] I also like breaking the stigma.
[1:46] Natural medicine or, alternative medicine
[1:49] has, certain things that said about it.
[1:52] And so I like to really bridge that gap
[1:54] and present a much more professional
[1:57] and medical opinion on that.
[2:00] It is a fantastically useful plant and I
[2:04] think some medicines and pharmaceuticals
[2:07] should be jealous of cannabis.
[2:08] What it does is incredible.
[2:11] It's definitely not just about getting
[2:13] high and we do like high at Home Hope.
[2:15] So we're going to do a bit of
[2:17] a walkthrough, just a little
[2:18] bit of an overview of cannabis.
[2:20] Then we're going to have, the
[2:21] amazing endocannabinoid ohm.
[2:23] So it's a little bit of
[2:24] a take on the holobiont.
[2:26] And endocannabinoid system, so we're
[2:28] doing a bit of a distribution and
[2:29] regulation and I'm not sure, has anyone
[2:32] heard of the term endocannabinoid tone?
[2:35] So, Ethan Russo also talks
[2:37] a lot, a lot about that.
[2:39] And then we'll talk about,
[2:40] amazing detection and correction
[2:42] strategies, along the same framework
[2:44] that we have here at HomeHope.
[2:48] Alright, so it all has to
[2:50] start at the beginning though.
[2:51] From the Tibetan Plateau, cannabis reached
[2:54] Europe approximately 6 million years ago.
[2:56] And it spread as far as eastern
[2:58] China by 1.2 million years ago.
[3:01] Here, really the origin
[3:03] of cannabis is far.
[3:05] . Fast spread, but the uses of
[3:07] cannabis, and being just a medicine,
[3:09] but it also is a bioaccumulator.
[3:11] It's a bit of a cleanup.
[3:13] So it does have phyto remediation
[3:15] properties and, can clean up
[3:18] heavy metals, radio, nucleotides,
[3:21] and much more from the soils.
[3:23] So this is also when we're looking at the
[3:26] quality of cannabis, we actually need to
[3:28] make sure that it is growing in the best
[3:31] possible way and this can affect outcomes.
[3:36] Okay.
[3:37] So the strains, we have a lot
[3:38] of different hybrids out there.
[3:40] So majority is hybrids, now, but
[3:43] we do have Sativa Indica, and there
[3:47] is a strain called Ruderalis, but
[3:49] mainly in the hybrid area as well.
[3:52] So, Sativa is known for its
[3:54] energizing and uplifting, and
[3:56] Indica particularly sedating.
[3:59] So, slightly different effects,
[4:00] and now they are combined
[4:02] to have different impacts.
[4:06] Alright, did we know that there was
[4:07] this many cannabinoids 100 or over 140?
[4:12] I think we're at about 144 at the moment.
[4:14] Different cannabinoids.
[4:16] The most well known being Delta
[4:18] nine or the lovely get high one
[4:22] and the cannabidol, which is a CBD.
[4:25] These compounds, they interact with the
[4:27] endocannabinoid system, and, this plays a
[4:30] role in regulating different physiological
[4:32] processes which we will go through.
[4:35] So there, that diagram is just a little
[4:36] bit more on the cannabinoid biosynthesis.
[4:41] So here, I really do love this diagram,
[4:44] and I created this for the module.
[4:46] It just gives a really good overview
[4:47] of different actions associated
[4:49] with your different cannabinoids.
[4:52] So CBD, as you can see in the
[4:53] middle, has a huge variety of
[4:55] different uses and actions.
[4:57] And then we go through CBC, CBG, CBGC,
[5:02] and CBN, which all of you have a little
[5:06] bit of a sneaky bit of CBN as well.
[5:08] It's a sedative and sleep inducing, and
[5:11] we also have Delta-9, Delta-8, and there's
[5:14] a few others that we don't know about.
[5:16] So that's a really good chart just
[5:18] to see the comprehensiveness of
[5:20] treatment options for cannabinoids.
[5:25] So we have some cannabinoids
[5:26] here gaining attention.
[5:28] So we have CBG, CBN.
[5:30] Delta 8 and Delta 10.
[5:33] Now Delta 8 got itself into a
[5:35] little bit of trouble recently but
[5:37] it does have psychoactive effects.
[5:39] So Delta 8 is also known to produce a
[5:42] less intense, high than Delta 9.
[5:44] So that's where it got a little
[5:46] bit more of its popularity,
[5:47] using beer and all sorts.
[5:49] And Delta 10 as well, so that has,
[5:51] psychoactive effects, but they're
[5:53] not too sure, and there's limited
[5:54] research on that at the moment.
[5:58] So here are some cannabinoids
[6:00] yet to gain attention.
[6:02] Now don't forget there is a hundred and,
[6:04] forty-four these are just some of them
[6:06] that we're going through here but again,
[6:09] little, research done on a lot of these.
[6:12] So we have CBND, CBE, CBL, and CBT.
[6:19] So some of these you may not have even
[6:21] seen pop up in any of the research.
[6:23] All right, so when I come to the
[6:30] entourage effect later on, then
[6:33] this is where we have cannabinoids
[6:36] and terpenes really making friends.
[6:39] When we have terpenes, terpenes are
[6:42] in multiple plant worlds, and we
[6:46] have more than 200 different terpenes.
[6:49] Terpenes make it have its distinct
[6:52] smell, and taste, but it also
[6:55] has been identified, for a lot
[6:57] of different therapeutic actions.
[6:59] So these therapeutic actions are listed
[7:01] here, again, in a lovely diagram,
[7:05] as I say that because I created it.
[7:07] Pinene, limonene, you know, limonene,
[7:09] obviously lemon, so there's some that
[7:11] you may recognize here, but they do
[7:14] have these as isolations, that can
[7:17] also be used for therapeutic use.
[7:23] Alright, so now we get to the good part.
[7:26] So, at Home Hope, and this is what I
[7:28] loved in my practice and this is what
[7:30] I wanted to bring more to my practice.
[7:33] Naturopathic medicine is holistic
[7:34] in itself, but what I love about
[7:37] health optimization medicine and
[7:38] practice is the dashboard, as
[7:40] Ted had spoken about earlier.
[7:42] And you really get a good understanding
[7:44] of exactly what your client is needing.
[7:47] And there's multiple dashboards
[7:49] across different tools
[7:51] that you can also be using.
[7:53] At HomeHope, a HoloBiont approach
[7:55] is taken, and understanding
[7:58] interdependence of all those
[7:59] systems, organs, and body parts,
[8:00] and the diverse community around it.
[8:02] So cannabis is components and
[8:04] interactions are no different.
[8:06] And so this is where the
[8:07] endocannabinoidome comes in.
[8:09] When we're looking at the entourage
[8:11] effect, it's the combination of
[8:14] cannabinoids, terpenes in cannabis
[8:17] medicine, and this was first proposed
[8:21] by Raphael, and the endocannabinoid
[8:23] system exhibits increased activity
[8:25] when the inactive metabolites are
[8:27] also closely related to the molecules.
[8:30] So, we're actually combining the
[8:32] whole plant really for optimal impact
[8:35] and optimal effect on our clients.
[8:38] Botanical drugs may be more effective
[8:39] than isolated components due to
[8:41] the entourage effect, which has
[8:43] been popularized by Ethan Russo.
[8:45] When we look at these specific
[8:47] treatments, we're actually making
[8:48] sure that we're actually matching
[8:50] some of these impacts across.
[8:52] And when they are combined,
[8:53] they definitely have more power.
[8:56] And I see that as more of a, even as
[8:57] a community of people, if you bind
[8:59] together and you have a lot more
[9:01] power, you have a lot more support.
[9:05] So here, when I found this diagram,
[9:07] I was so excited and I said to Dr.
[9:09] Ted, I'm like, Dr.
[9:09] Ted, I found something like the holobiont!
[9:13] And I don't know if he was
[9:14] as excited as me, but I was.
[9:15] When you have here, this diagram,
[9:17] explains that really exclusive, huge
[9:21] expanded endocannabinoid system.
[9:24] So the interaction between lipid
[9:26] mediators, 20 biosynthetic inactivated
[9:29] enzymes, more than 20 molecular
[9:31] targets, and so much more.
[9:34] So this all regulates and maintains
[9:36] a homeostasis by regulating
[9:37] pain, appetite, mood, immunity,
[9:39] stress response, sleep, and more.
[9:45] So now we dive into the actual
[9:48] endocannabinoid system, and
[9:50] it is a relatively new system.
[9:52] So we'll talk here about endocannabinoid
[9:55] receptors, and how we actually have
[9:58] these beautiful use of endocannabinoids
[10:01] within ourselves as well.
[10:03] So here, this diagram just really
[10:04] explains more, visually about the
[10:07] expanse and the spread of CB1 and
[10:12] CB2 receptors across the whole body.
[10:14] There is not many places that these
[10:16] receptors don't reach in the body.
[10:19] It is an all encompassing system, and as
[10:22] I said, there is only a small amount of
[10:24] areas that aren't covered by this system.
[10:26] What we have is our own endocannabinoids
[10:29] and cannabinoids that can interact
[10:32] with these particular receptors.
[10:37] So CB1 is primarily located in
[10:40] the central nervous system and the
[10:42] brain, and the first to be isolated.
[10:45] CB2 receptors are present in the immune
[10:47] system and specific immune cells.
[10:50] We also have, throughout the central
[10:52] nervous system and also they play a role
[10:54] in the effect of the cannabinoids on
[10:56] inflammation and immunological function.
[10:58] So there is a little bit
[11:00] of information there about
[11:01] where they exhibit the effects.
[11:03] They also modulate the
[11:04] activity of the calcium and the
[11:05] potassium channels ion channels.
[11:09] So here we have more
[11:10] cannabinoid receptors.
[11:12] Now there are a few more, but
[11:14] these are the major ones that I
[11:15] wanted to present to you today.
[11:17] So you had a really good overall,
[11:19] information, area for cannabis.
[11:22] GPR18 is recently discovered, a
[11:25] non CB1, CB2 receptor expressed
[11:27] in the immune tissues and exerts a
[11:30] variety of physiological effects,
[11:32] and it's still being investigated.
[11:34] GPR55 is activated by cannabinoids
[11:36] like THC and CBD as well as
[11:39] endogenous cannabinoids like 2AG,
[11:41] which I'll talk about in a minute.
[11:42] And anandamide, which
[11:44] is our beautiful bliss.
[11:46] So TRP V1.
[11:48] And this compound gives spicy peppers,
[11:51] their heat, and it can also be activated
[11:54] by cannabinoids and anandamide and THC.
[11:57] This is really closely
[11:58] involved in pain perception.
[12:01] So, when I'm treating my, my clients,
[12:05] , and I was asked this last night, and
[12:07] it's really, hard to pick out all these
[12:09] tools that we are constantly learning.
[12:12] And cannabis is just one of
[12:14] those parts of the tools.
[12:15] However, because of its expanse
[12:18] across the whole body, it can have so
[12:21] many uses, but it's set and setting.
[12:25] And it really is important to
[12:26] actually know when and how and
[12:29] where and what, just like any other
[12:31] tool that we're using to put it in.
[12:33] I will talk through a little bit more
[12:34] about posology, which is docid, later
[12:37] on, but when we have our own use for
[12:40] these receptors and these are anandamide.
[12:43] And these are our own endocannabinoids,
[12:46] and so they can actually help bind and
[12:50] support our receptor strength as well.
[12:52] So this binds to CB1 receptor, anandamide.
[12:56] This is the runner's high, so you go for
[12:59] a run and you feel on top of the world.
[13:01] It is the most amazing feeling.
[13:03] Unfortunately, I get that, but I also
[13:05] have a genetic trait that will break
[13:09] down my anandamide too quickly, which I
[13:11] found out when I did the genetic testing.
[13:13] So I have to do lots of running.
[13:15] So associated also with mood
[13:17] regulation And pleasure.
[13:20] Anandamide's effects are diverse and can
[13:22] include pain modulation, appetite control,
[13:25] and regulation of stress responses.
[13:27] And it is synthesized on
[13:28] demand and in response to
[13:30] specific physiological signals.
[13:33] So, as I said, it is broken down by FAAH,
[13:37] and that is unfortunately my problem.
[13:39] So I'm more susceptible to stress
[13:41] if I don't have enough anandamide.
[13:44] 2AG is another, so these are
[13:46] also called our signaling
[13:48] molecules, these endocannabinoids.
[13:51] So 2AG, prominent endocannabinoid,
[13:53] it interacts with both receptors and
[13:56] it's found in high concentrations
[13:57] in the central nervous system.
[14:00] And 2AG plays a significant role in
[14:01] modulating pain, perception, inflammation,
[14:05] immune responses and neuroprotection.
[14:08] So it is produced in larger quantities,
[14:11] than compared to anandamide, and
[14:13] it's stored in cell membranes where
[14:14] it can be released as needed in
[14:16] response to physiological states.
[14:20] So we also have
[14:21] endocannabinoid like compounds.
[14:22] So we have NADA, PEA,
[14:25] OEA, and also 2- AGE.
[14:30] Because of my systematic mind, and
[14:32] I like to treat, and I like to know,
[14:35] and I'm very inquisitive around
[14:36] all of this, you know, well, how do
[14:39] we know what we're going to treat?
[14:42] Or how do we know if we need to treat?
[14:44] These are the biggest questions, like,
[14:45] I've got cannabis, who needs to use it?
[14:48] How am I going to determine this?
[14:49] So, this is where detection comes in.
[14:52] And this is again part of the
[14:53] framework for health optimization
[14:54] medicine and practice.
[14:56] So we can assess tone, and I'll talk a
[14:57] little bit more about tone in a minute.
[14:59] And this is a major part of detection.
[15:02] We can use reports like endoDNA
[15:05] the one that I was talking
[15:06] about before where you can
[15:07] actually test your, addiction.
[15:09] You can, test your, breakdown.
[15:11] You can test your specific surrounding
[15:14] need for certain ratios with, cannabis.
[15:18] You can also test the plasma,
[15:19] but it's quite invasive.
[15:20] The cerebral spine, spinal fluid.
[15:23] And as Kiran told me last night,
[15:25] there is GI testing that can
[15:27] test for receptor strength.
[15:30] We have multiples and I'm sure there is
[15:32] a lot more to come in terms of testing
[15:35] for detection of endocannabinoid system.
[15:38] So therefore, how do we correct?
[15:40] And correction comes from
[15:41] phytoendocannabinoids, using correct
[15:43] posology, which I call it, you
[15:45] know, it's a dosing, and home height
[15:47] foundational health balancing.
[15:49] You want that brickwork, and this is what,
[15:51] in a very simple term, we talk about at
[15:53] Health Optimization Medicine and Practice.
[15:55] It's that foundational brickwork, so
[15:57] therefore we can optimize on top of that.
[16:00] And that is the, um, the beautiful
[16:03] picture of health optimization.
[16:07] Alright, so the endocannabinoid
[16:08] tone theory, or ECT, or clinical
[16:11] endocannabinoid deficiency.
[16:12] So here we have low and high symptoms,
[16:15] so you can track via symptoms, so you
[16:18] can assess via symptoms, and this
[16:21] little part here, this is actually just
[16:24] a section out of my test, and it shows
[16:26] that, I do have a higher breakdown.
[16:29] So the individual endocannabinoid
[16:31] tone reflects the levels of
[16:32] endocannabinoids like anandamide and
[16:35] 2AG and their synthesis, catabolism
[16:38] and cannabinoid receptor density.
[16:40] So deficiency may cause conditions like
[16:42] migraine, fibromyalgia, irritable bowel
[16:44] syndrome and pain while excess may occur
[16:47] in obesity and metabolic conditions
[16:49] as you can see on that diagram there.
[16:52] So decreased tone may
[16:54] lower pain threshold.
[16:55] So that's some of the things that
[16:56] you can see with clients, and
[16:57] impact digestion, mood, and sleep.
[17:01] So tone can decrease also due to
[17:03] genetic and congenital injury or
[17:05] disease related reasons as well.
[17:09] So this little diagram down the
[17:10] bottom here is the trifecta,
[17:14] coined by Russo as well.
[17:15] This is more common in women and
[17:17] I've seen this in a few of my
[17:18] clients, which has been fascinating
[17:20] after I did the research here.
[17:23] And you see a combination of these,
[17:26] different symptoms, whether it's all
[17:27] three or two, migraine, fibromyalgia,
[17:31] irritable bowel, more common in women.
[17:33] And this is, significant of
[17:34] a low endocannabinoid tone.
[17:38] All right.
[17:39] So pathology, cannabis is a different
[17:43] ball game when coming to prescribing.
[17:45] It can be overwhelming, it can be,
[17:48] really confusing for practitioners who
[17:51] are used to prescribing in other ways.
[17:53] So it is important to remember that
[17:55] this THC and CBD in other parts of
[17:57] the plant, of the cannabis plant
[17:58] can be biphasic in properties.
[18:01] Low can give.
[18:02] Low and high doses, so they generate the
[18:04] opposite effect, so low can produce high
[18:08] effects and high can produce low effects.
[18:11] So starting slow and going
[18:13] slow, is really the key when it
[18:16] comes to cannabis prescribing.
[18:18] So it can be very effective at low dose.
[18:21] So I'll show you, a teeter strategy,
[18:23] so it's really, important, and
[18:25] I've noticed this through my clients
[18:26] as well, is to teeter, or titer
[18:28] the dose really, really slowly.
[18:30] And you can actually get to a point
[18:32] where you're getting impact and
[18:33] then bring that back down again.
[18:34] And it's individual for each and every
[18:37] person, so you can't give a specific dose
[18:40] for one person and expect to suit all as
[18:43] we do with all of the other medicines.
[18:45] So here you can see a little
[18:46] bit of an idea there and the
[18:48] interactions that it has within
[18:50] the within the enzymes as well.
[18:52] So we have the CBD and also CBN and THC.
[18:58] So here, is just a bit of an example of
[19:01] what it might look like, to see a little
[19:03] bit of a tater dosing strategy there.
[19:06] There's also so many forms of cannabis.
[19:09] And that is the confusing part as
[19:11] well, we've got smoking, vaporizing,
[19:13] edibles, juicing, tinctures, capsules,
[19:16] suppositories, and topical as well.
[19:18] What do we choose?
[19:19] And that's also considerations
[19:21] for our clients as well.
[19:23] Vaporizing is preferable over smoking.
[19:26] Smoking, we do have impacts on the lungs.
[19:29] Everyone knows the side effects of THC.
[19:31] Alright.
[19:33] That's the one that obviously gets us
[19:35] high, but it can be disorientating, so
[19:36] that can come with dizziness, it can
[19:38] come with, feeling a little bit nauseous,
[19:40] same with CBD, but there's more of us
[19:42] know the side effects, and it can be
[19:45] unpleasant for some and pleasant for
[19:46] some, depending on what you're expecting
[19:48] and the dose that you're using for these.
[19:51] Although normally CBD is relatively
[19:53] safe and doesn't come with side
[19:55] effects, it can have a few, and
[19:57] these are the ones that, we look at.
[19:59] So sedation, decreased appetite,
[20:01] elevated liver function tests, vomiting,
[20:04] pneumonia, and there's some that can
[20:06] lead to a little bit of, , tiredness and
[20:09] then obviously not recommended to smoke
[20:11] because of the side effects on the lungs.
[20:15] All right, so it wouldn't be complete
[20:19] without looking at what else you can
[20:20] do for your endocannabinoid system.
[20:23] But fats is a big one to have as a
[20:25] combination with your CBD, and they
[20:28] found that it was increased by 14 times
[20:31] in the blood when consumed with fats.
[20:33] In this little diagram here, all of
[20:35] these are huge components of, being
[20:38] healthy, of your endocannabinoid
[20:40] system health, and this is, social
[20:43] interactions pulled out there, just
[20:45] as an example, but all of these things
[20:48] are equally as important to balance
[20:50] a really good endocannabinoid system.
[20:54] All right, so we have
[20:55] some misconceptions here.
[20:58] There's concerns obviously, the stigma
[21:00] surrounding cannabis the more we
[21:01] know about it and the way that we
[21:03] can see it grown and all these other
[21:05] things is really, really important.
[21:07] So we have here some quality
[21:09] variances at alteration, we've
[21:11] got the pesticide residue, heavy
[21:13] metal contamination, being that
[21:15] bioaccumulator, it can take on a lot more.
[21:19] So the use of various growth hormones,
[21:21] they all affect the profile of the
[21:23] cannabinoids and the terpenes as well.
[21:26] So IQ is a huge one.
[21:27] Jodi: A lot of people
[21:27] associate cannabis with low IQ.
[21:30] That's where the stoner
[21:31] and the pothead comes in.
[21:34] And, increased consumption has been
[21:36] associated with lower short term memory.
[21:38] However, they found that this is not
[21:40] a permanent change and it generally
[21:42] resolves, except when there has
[21:44] been chronic use at a younger age.
[21:47] And this is the same
[21:48] with psychosis as well.
[21:49] So we can test for schizophrenic
[21:52] tendencies through genetics.
[21:54] And this is what I recommend to those who
[21:56] have had any experience or bad experience
[21:59] with cannabis in the past to make
[22:00] sure that we don't have susceptibility
[22:02] towards schizophrenia or psychosis.
[22:05] And then we're actually
[22:06] looking at more likely being a
[22:08] genetic issue if that happens.
[22:11] it's not high risk, but there's
[22:12] definitely an increased risk in some.
[22:14] And those also who have consumed it at
[22:17] a very young age in a developing brain.
[22:19] So addiction and dependence, some
[22:21] of these tests that you can, see
[22:23] who's more likely to become
[22:24] addicted to substances and not.
[22:26] 4 percent compared to 14 percent
[22:29] alcohol, what's worse, yeah?
[22:32] Now, fertility is a big one.
[22:33] There's more research that is needed.
[22:35] THC is mainly associated with the
[22:37] fertility issues, reduced sperm quality
[22:39] and menstrual cycle disturbances.
[22:41] Obviously not recommended in pregnancy
[22:44] and normally with my clients, I
[22:46] tell them to avoid cannabis for a
[22:48] period of time, especially when I'm
[22:49] looking at my fertility clients.
[22:51] Now,
[22:51] Jodi Duval_Cannabis for Health Optimization:
[22:51] I found personal lubricants, inhalers,
[22:54] inhalable powders, toothpaste,
[22:57] breast strips, pet products, and
[23:00] beer, cocktails, it goes on.
[23:04] So, there's so much more
[23:05] coming out at the moment.
[23:07] However, as you can imagine,
[23:08] , there is consumer issues.
[23:10] We have quality, consistency, dosing,
[23:13] we have cultivation practices, tracking,
[23:16] pesticides and chemical residues,
[23:18] molds and fungus, heavy metals,
[23:20] microbial contamination, and it goes on.
[23:23] Standardization, testing
[23:25] challenges, regulatory oversight.
[23:27] Label and packaging, confusing
[23:28] packaging, and this is where
[23:29] Delta A got itself into trouble.
[23:31] You can get 10 milligram THC beer
[23:34] with the effect in 20 to 30 minutes.
[23:37] Overall I really wanted you guys all
[23:39] to take away from this is that the
[23:41] curiosity for cannabis, to have an ability
[23:45] to see it as something quite special.
[23:47] It's this overarching, impact on
[23:49] this system behind a system, which I
[23:51] call it, and the endocannabinoidome,
[23:53] which is this intricate, huge part
[23:57] of controlling so many different
[23:59] physiological processes within our body.
[24:01] So thank you for listening to me.
[24:03] And we do have the advanced cannabis
[24:07] course, if anyone is wondering.
[24:09] So if you want more,
[24:10] it's a lot more in there.

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