# Live From WCLC 2025: Tuesday Highlights & Meeting Summary

An episode of [Lung Cancer Considered](https://invisiblenetwork.ai/podcast/1655997630), 9 Sep 2025, 44 min.

Audio: https://feeds.soundcloud.com/stream/2167561068-lungcancerconsidered-live-from-wclc-2025-tuesday-highlights-meeting-summary.mp3

In this special WCLC 2025 episode of Lung Cancer Considered, hosts Dr. Narjust Florez and Dr. Stephen Liu discuss highlights from the conference. Dr. Susan Scott discusses EGFR mutant NSCLC and results from PALOMA-2 and subcutaneous amivantamab. Dr. Wenfeng Fang discusses Iza-Bren (BL-D01D1), a first-in-class EGFR x HER-3 biospecific ADC linked to a novel topoisomerase I inhibitor payload, with promising preliminary activity in EGFR positive previously treated NSCLC. Dr. Biagio Ricciuti shares his insights from WCLC 2025, including the FLAURA-2 OS readout, the HARMONi trial in EGFR positive NSCLC, and his research in the use of immunotherapy in early-stage lung cancer.

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