# Fertility Q&A: Endometriosis, PCOS, Ectopic Pregnancy & More

An episode of [As a Woman](https://invisiblenetwork.ai/podcast/1449553339), 5 Apr 2026, 10 min.

Audio: https://pdst.fm/e/pscrb.fm/rss/p/traffic.megaphone.fm/PCL6520759082.mp3

Dr. Natalie Crawford, board-certified OB-GYN and REI, answers your fertility questions. • I’m on Lupron for suspected endometriosis and have been on suppression for almost two months, but I’m noticing vaginal cramping, ovarian pain, shooting rectal pain, and increased pain with intercourse. Is it normal to have increased pain during Lupron suppression, or does this suggest something else is going on? • How long, on average, should someone with PCOS and insulin resistance stay on metformin, especially when trying to conceive or undergoing fertility treatment? • I recently had an ectopic pregnancy located on my ovary. Is this typically just bad luck, or are there underlying risk factors that increase the likelihood of this happening again? • After experiencing an ectopic pregnancy, is there anything specific I should do as soon as I get a positive pregnancy test in the future to ensure everything is progressing safely? • When trying to conceive, when should retinol be discontinued? Is it safe to continue using it up until a positive pregnancy test, or should it be stopped earlier? • I regularly take creatine (about 5–10 grams per day). Is it safe to continue using creatine while trying to conceive or during pregnancy? Pre-order Dr. Crawford's debut book, The Fertility Formula, now! https://www.nataliecrawfordmd.com/book Want your questions answered on the next episode? Ask them here! https://www.nataliecrawfordmd.com/qa-submissions Learn more about your ad choices. Visit megaphone.fm/adchoices

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