# #472 DIGEST: cfDNA & cancer in Pregnancy, Vitamin K2 for Leg Cramps, PRN anti-hypertensives, GLP-1 Agonists for AUD, Short-Course Antibiotics

An episode of [The Curbsiders Internal Medicine Podcast](https://invisiblenetwork.ai/podcast/1198732014), 24 Feb 2025, 51 min.

Audio: https://clrtpod.com/m/pscrb.fm/rss/p/dts.podtrac.com/redirect.mp3/audioboom.com/posts/8658279.mp3?modified=1780831642&sid=5034728&source=rss

Join us as we review recent articles and news featured in The DIGEST issues #59-61, including cfDNA and incidental detection of cancer in pregnancy, vitamin K2 for nocturnal leg cramps, the danger of as-needed anti-hypertensive medications in the hospital, GLP-1 agonists for alcohol use disorder, short-course (7 vs 14 days) antibiotics for bacteremia, and patient-collected HPV testing for cervical cancer screening. Fill your brain hole with a fully digestible meal! Featuring Laura Glick MD, Nora Taranto (@norataranto), Paul Williams (@paulnwilliamz), and Matt Watto (@doctorwatto). Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments • 00:00 Introduction and Overview • 02:57 The IDENTIFY study: Non-Invasive Prenatal Testing and Cancer Detection with cfDNA • 05:54 Implications of Non-Reportable Results in Prenatal Testing • 08:51 Vitamin K2: A New Approach to Managing Nocturnal Leg Cramps • 12:07 Practicality and Future of Vitamin K2 in Clinical Practice • 23:21 The Dangers of As-Needed Antihypertensives in the hospital • 32:21 Exploring GLP-1 Agonists for Alcohol Use Disorder • 40:24 Shorter Antibiotic Courses in Sepsis • 46:09 Advancements in Patient-Collected HPV Screening for cervical cancer Credits • Written and Produced by: Nora Taranto MD, Laura Glick MD, Matthew Watto MD, FACP; Paul Williams MD, FACP • Show Notes: Nora Taranto MD • Cover Art: Matthew Watto MD, FACP • Hosts: Nora Taranto MD, Laura Glick MD, Matthew Watto MD, FACP; Paul Williams MD, FACP • Reviewer: Emi Okamoto MD • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP • Technical Production: PodPaste Disclosures The Curbsiders report no relevant financial disclosures. Sponsor: Bombas Head over to Bombas.com/curb and use code curb for 20% off your first purchase. Sponsor: Pretty Litter Go to PrettyLitter.com/curb to save twenty percent on your FIRST order and get a free cat toy. Sponsor: Rocket Money Cancel your unwanted subscriptions and reach your financial goals faster with Rocket Money. Go to RocketMoney.com/CURB today.

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