# #392 Live! Opioid and Xylazine Withdrawal in the Hospital

An episode of [The Curbsiders Internal Medicine Podcast](https://invisiblenetwork.ai/podcast/1198732014), 26 Apr 2023, 45 min.

Audio: https://clrtpod.com/m/pscrb.fm/rss/p/dts.podtrac.com/redirect.mp3/audioboom.com/posts/8286418.mp3?modified=1682582192&sid=5034728&source=rss

Dominate opioid and xylazine (aka tranq) withdrawal in the hospital with expert insights from Dr. Joseph D’Orazio (@dorazepam) recorded LIVE! at Pennsylvania Hospital Grand Rounds in Philadephia, PA. Xylazine, an alpha-2 adrenergic agonist, has emerged as a frequent contaminant in the opioid supply with a distinct withdrawal syndrome. You’ll learn to manage this common withdrawal syndrome while also addressing acute pain complaints and opioid withdrawal. Sorry, no CME for this episode, but check out CME for past episodes at curbsiders.vcuhealth.org. Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments • Intro • Xylazine basics • Management of xylazine withdrawal • Opioid withdrawal and acute pain • Outpatient considerations for xylazine • Audience questions • Outro Credits • Writer and Producer: Matthew Watto MD, FACP • Infographic and Cover Art: Matthew Watto MD, FACP • Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP • Reviewer: Emi Okamoto MD • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP • Technical Production: PodPaste • Guest: Joseph D’Orazio MD Full transcript available HERE

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