# Multidimensional NMR Spectroscopy for Structural Studies of Biomolecules - Institution: IISc Bangalore - Department: Chemistry and Biochemistry - Teacher: Prof. Hanudatta S. Atreya - Level: Undergraduate - Language: English - Subjects: Chemistry - Source: [NPTEL](https://nptel.ac.in/courses/104108097) - Licence: [CC BY-NC-SA](https://nptel.ac.in/faq) (Non-commercial use only.) - Syllabus: [at the source](https://nptel.ac.in/courses/104108097) - Who can watch: Tweens profiles and older (sources give no ratings; placed by Invisible Network from the source's own words) ## Lectures 1. [Introduction to NMR spectroscopy](https://invisiblenetwork.ai/learn/nptel/104108097/c17df4eac1e1) (Video) 2. [Energy levels in NMR spectroscopy: Quantum mechanical model and Vector model](https://invisiblenetwork.ai/learn/nptel/104108097/55c4db22cfd0) (Video) 3. [Observing the NMR signal](https://invisiblenetwork.ai/learn/nptel/104108097/07a6712d64d6) (Video) 4. [Basic concepts in 1D NMR: Chemical shift and Spin-spin coupling](https://invisiblenetwork.ai/learn/nptel/104108097/01932127cf24) (Video) 5. [Basic concepts in 1D NMR: Nuclear Spin Relaxation, 1H NMR and 13C NMR](https://invisiblenetwork.ai/learn/nptel/104108097/b55cce29f0e8) (Video) 6. [Basic concepts in 2D NMR spectroscopy](https://invisiblenetwork.ai/learn/nptel/104108097/0d8e4d391ec3) (Video) 7. [Principles of 2D correlation spectroscopy COSY](https://invisiblenetwork.ai/learn/nptel/104108097/314f7708c251) (Video) 8. [Principles of 2D Total correlation spectroscopy (TOCSY)](https://invisiblenetwork.ai/learn/nptel/104108097/d57d0c321c93) (Video) 9. [2D Nuclear Overhauser Effect Spectroscopy (NOESY)](https://invisiblenetwork.ai/learn/nptel/104108097/ce8b86b20eaf) (Video) 10. [2D NOESY and 2D ROESY](https://invisiblenetwork.ai/learn/nptel/104108097/d17399e39749) (Video) 11. [Principles of 2D Heteronuclear NMR](https://invisiblenetwork.ai/learn/nptel/104108097/b3c705a383c2) (Video) 12. [2D Heteronuclear NMR: HSQC](https://invisiblenetwork.ai/learn/nptel/104108097/c21e7dcc7b41) (Video) 13. [Heteronuclear multiple quantum coherence (HMQC) and single quantum coherence (HSQC) - Part I](https://invisiblenetwork.ai/learn/nptel/104108097/29654ef58326) (Video) 14. [Heteronuclear multiple quantum coherence (HMQC) and single quantum coherence (HSQC) - Part II](https://invisiblenetwork.ai/learn/nptel/104108097/0dc5f64ec1d4) (Video) 15. [2D HSQC-TOCSY](https://invisiblenetwork.ai/learn/nptel/104108097/f0d4c944605a) (Video) 16. [3D NMR Spectroscopy - part I](https://invisiblenetwork.ai/learn/nptel/104108097/afc3b6901bc9) (Video) 17. [3D NMR Spectroscopy - part II](https://invisiblenetwork.ai/learn/nptel/104108097/20a49641492c) (Video) 18. [3D HNCA and 3D HNCO](https://invisiblenetwork.ai/learn/nptel/104108097/b081381144f6) (Video) 19. [3D HNCACB and 3D HN(CO)CACB](https://invisiblenetwork.ai/learn/nptel/104108097/aa5939da00bb) (Video) 20. [Protein Backbone resonance assignment and side chain resonance assignment](https://invisiblenetwork.ai/learn/nptel/104108097/7187ddcd79f9) (Video) 21. [Basic concepts of protein structure](https://invisiblenetwork.ai/learn/nptel/104108097/7d09a9e5435b) (Video) 22. [Introduction to Structure Determination of Bio-Molecules by NMR](https://invisiblenetwork.ai/learn/nptel/104108097/db65d35ca7ae) (Video) 23. [Over-expression of proteins in Bacteria](https://invisiblenetwork.ai/learn/nptel/104108097/a70801e6551b) (Video) 24. [Isotope labeling of proteins for NMR studies - Part I](https://invisiblenetwork.ai/learn/nptel/104108097/5ec58f84f41a) (Video) 25. [Isotope labeling of proteins for NMR studies - Part II](https://invisiblenetwork.ai/learn/nptel/104108097/2b6f15dca462) (Video) 26. [Isotope labeling of proteins for NMR studies - Part III](https://invisiblenetwork.ai/learn/nptel/104108097/3a47160f015d) (Video) 27. [Isotope labeling of proteins for NMR studies - Part IV](https://invisiblenetwork.ai/learn/nptel/104108097/53b286d36be6) (Video) 28. [Resonance assignments of Proteins - Part I](https://invisiblenetwork.ai/learn/nptel/104108097/71cd2f78a9ae) (Video) 29. [Resonance assignments of Proteins - Part II](https://invisiblenetwork.ai/learn/nptel/104108097/4cd8ace8c2fd) (Video) 30. [Resonance assignments of Proteins - Part III](https://invisiblenetwork.ai/learn/nptel/104108097/908bdc9d6395) (Video) 31. [Determination of protein secondary structure from NMR data: CSI method](https://invisiblenetwork.ai/learn/nptel/104108097/69c7605b943e) (Video) 32. [Determination of protein secondary structure from NMR data: J coupling based method](https://invisiblenetwork.ai/learn/nptel/104108097/62c22c97390e) (Video) 33. [Determination of protein tertiary structure from NMR data - part I](https://invisiblenetwork.ai/learn/nptel/104108097/9ee44d72a2b1) (Video) 34. [3D NOESY HSQC](https://invisiblenetwork.ai/learn/nptel/104108097/aafe33018895) (Video) 35. [Determination of protein tertiary structure from NMR data - part II](https://invisiblenetwork.ai/learn/nptel/104108097/ba2c35cb1e8d) (Video) 36. [Understanding Protein ligand interaction by NMR: Chemical shift perturbation](https://invisiblenetwork.ai/learn/nptel/104108097/d64cb7e1fb30) (Video) 37. [Understanding Protein ligand interaction by NMR: Chemical exchange](https://invisiblenetwork.ai/learn/nptel/104108097/ddf150397349) (Video) 38. [Understanding Protein ligand interaction by NMR: T2 Filter](https://invisiblenetwork.ai/learn/nptel/104108097/cb857c45b2b2) (Video) 39. [Understanding Protein ligand interaction by NMR: STD NMR](https://invisiblenetwork.ai/learn/nptel/104108097/a0990b45654e) (Video) 40. [Understanding Protein ligand interaction by NMR: Transfer NOE NMR](https://invisiblenetwork.ai/learn/nptel/104108097/d10be9a05217) (Video) 41. [Understanding Protein ligand interaction by NMR : Diffusion ordered Spectroscopy (DOSY) - Part I](https://invisiblenetwork.ai/learn/nptel/104108097/580a316cb8b5) (Video) 42. [Understanding Protein ligand interaction by NMR : Diffusion ordered Spectroscopy (DOSY) - Part II](https://invisiblenetwork.ai/learn/nptel/104108097/907f5685ecc3) (Video)