# NMR Spectroscopy for Structural Biology

- Institution: IIT Bombay
- Department: Chemistry and Biochemistry
- Taught by: Prof. Ashutosh Kumar, Prof. R. V Hosur
- Level: Graduate
- Language: English
- Subjects: Chemistry
- Source: [NPTEL](https://nptel.ac.in/courses/104101135)
- Licence: [CC BY-NC-SA](https://nptel.ac.in/faq) (Non-commercial use only.)
- Syllabus: [at the source](https://nptel.ac.in/courses/104101135)
- Who can watch: Teens profiles and older (sources give no ratings; placed by Invisible Network from the source's own words)

This course will start with Basic principles of NMR, Discuss practical aspects of NMR spectroscopy, peptide NMR, Protein NMR, Nucleic acids NMR. We will teach with examples how to solve structure and measure dynamics using NMR.

Intended audience: M.Sc./ PhD students &amp; Scientist, and Scientists working in Biopharma Industries.

Prerequisites: Under graduate level understanding of Physics and Mathematics, Basic course on NMR spectroscopy.INTENDED AUDIENCE: M.Sc./ PhD students &amp; Scientist, and Scientists working in Biopharma Industries.

## Lectures

1. [Lecture 1 : NMR Basic Concepts - I](https://invisiblenetwork.ai/learn/nptel/104101135/838c9f8cf236) (YouTube)
2. [Lecture 2 : NMR Basic Concepts - II](https://invisiblenetwork.ai/learn/nptel/104101135/6a201e5278ef) (YouTube)
3. [Lecture 3 : NMR Basic Concepts - III](https://invisiblenetwork.ai/learn/nptel/104101135/21dece4409a8) (YouTube)
4. [Lecture 4 : NMR Basic Concepts - IV](https://invisiblenetwork.ai/learn/nptel/104101135/6094465bfc14) (YouTube)
5. [Lecture 5 : NMR Spectra of Molecules](https://invisiblenetwork.ai/learn/nptel/104101135/9ba7d64c4430) (YouTube)
6. [Lecture 6 : Chemical Shifts and Coupling constant](https://invisiblenetwork.ai/learn/nptel/104101135/2d09fb062699) (YouTube)
7. [Lecture 7 : Fine Structures in NMR Spectra](https://invisiblenetwork.ai/learn/nptel/104101135/5c26c9b8f45d) (YouTube)
8. [Lecture 8 : Pulse Excitation and FT-NMR](https://invisiblenetwork.ai/learn/nptel/104101135/485c4210a68b) (YouTube)
9. [Lecture 9 : Practical Aspects of FT-NMR - I](https://invisiblenetwork.ai/learn/nptel/104101135/bb66462e8d20) (YouTube)
10. [Lecture 10 : Practical Aspects of FT-NMR - II](https://invisiblenetwork.ai/learn/nptel/104101135/f3a55b3c1aff) (YouTube)
11. [Lecture 11 : Practical Aspects of FT-NMR 3](https://invisiblenetwork.ai/learn/nptel/104101135/b49a5f6fae10) (YouTube)
12. [Lecture 12 : Practical Aspects of FT-NMR 4](https://invisiblenetwork.ai/learn/nptel/104101135/84251ffcda7a) (YouTube)
13. [Lecture 13 : Polarization Transfer Technique](https://invisiblenetwork.ai/learn/nptel/104101135/fb7c11b2b472) (YouTube)
14. [Lecture 14 : Polarization Transfer Technique 2](https://invisiblenetwork.ai/learn/nptel/104101135/c1cbdc492333) (YouTube)
15. [Lecture 15 : General Concept of Multidimensional NMR 1](https://invisiblenetwork.ai/learn/nptel/104101135/b1b911af246b) (YouTube)
16. [Lecture 16 : General Concept of Multidimensional NMR 2](https://invisiblenetwork.ai/learn/nptel/104101135/32d718d98dfe) (YouTube)
17. [Lecture 17 : 2-D NMR or 2-D Co-relation spectroscopy : General concept 1](https://invisiblenetwork.ai/learn/nptel/104101135/33c7ffe46320) (YouTube)
18. [Lecture 18 : 2-D NMR or 2-D Co-relation spectroscopy : General concept 2](https://invisiblenetwork.ai/learn/nptel/104101135/9a32dd776f80) (YouTube)
19. [Lecture 19 : 2-D NMR or 2-D Co-relation spectroscopy : General concept 3](https://invisiblenetwork.ai/learn/nptel/104101135/b13ca1c5d0ec) (YouTube)
20. [Lecture 20 : Introduction to NOESY and HSQC 1](https://invisiblenetwork.ai/learn/nptel/104101135/f660fdd8e834) (YouTube)
21. [Lecture 21 : Introduction to NOESY and HSQC 2](https://invisiblenetwork.ai/learn/nptel/104101135/2ef8ab1d980b) (YouTube)
22. [Lecture 22 : Introduction to NOESY and HSQC 3](https://invisiblenetwork.ai/learn/nptel/104101135/5b685b38e836) (YouTube)
23. [Lecture 23 : Introduction to NOESY and HSQC 4](https://invisiblenetwork.ai/learn/nptel/104101135/58d59b862708) (YouTube)
24. [Lecture 24 : Application of NMR in the area of structural Biology: Structure of DNA and RNA 1](https://invisiblenetwork.ai/learn/nptel/104101135/8d6d4fdaac16) (YouTube)
25. [Lecture 25 : Application of NMR in the area of structural Biology: Structure of DNA and RNA 2](https://invisiblenetwork.ai/learn/nptel/104101135/f15d593ee459) (YouTube)
26. [Lecture 26 : Application of NMR in the area of structural Biology: Structure of DNA and RNA 3](https://invisiblenetwork.ai/learn/nptel/104101135/92be5dec25c0) (YouTube)
27. [Lecture 27 : Application of NMR in the area of structural Biology: Structure of DNA and RNA 4](https://invisiblenetwork.ai/learn/nptel/104101135/3faa5921fba8) (YouTube)
28. [Lecture 28 : Application of NMR in the area of structural Biology: Structure of DNA and RNA 5](https://invisiblenetwork.ai/learn/nptel/104101135/e7928b01250c) (YouTube)
29. [Lecture 29 : Application of NMR in the area of structural Biology: Structure of DNA and RNA 6](https://invisiblenetwork.ai/learn/nptel/104101135/c46a864de335) (YouTube)
30. [Lecture 30 : Application of NMR in the area of structural Biology: Structure of DNA and RNA 7](https://invisiblenetwork.ai/learn/nptel/104101135/8619fc451207) (YouTube)
31. [Lecture 31 : Determination of Structure and Dynamics of Proteins-1](https://invisiblenetwork.ai/learn/nptel/104101135/1afa3423ae46) (YouTube)
32. [Lecture 32 : Determination of Structure and Dynamics of Proteins-2](https://invisiblenetwork.ai/learn/nptel/104101135/275280fab35c) (YouTube)
33. [Lecture 33 : Determination of Structure and Dynamics of Proteins-3](https://invisiblenetwork.ai/learn/nptel/104101135/ba2ebf08975b) (YouTube)
34. [Lecture 34 : Determination of Structure and Dynamics of Proteins-4](https://invisiblenetwork.ai/learn/nptel/104101135/ce422ae1c892) (YouTube)
35. [Lecture 35 : Determination of Structure and Dynamics of Proteins-5](https://invisiblenetwork.ai/learn/nptel/104101135/4da13d164065) (YouTube)
36. [Lecture 36 : Determination of Structure and Dynamics of Proteins-6](https://invisiblenetwork.ai/learn/nptel/104101135/5d4629be071a) (YouTube)
37. [Lecture 37 : NMR Analysis of Protein Dynamics I](https://invisiblenetwork.ai/learn/nptel/104101135/4b74bc56f02d) (YouTube)
38. [Lecture 38 : NMR Analysis of Protein Dynamics II](https://invisiblenetwork.ai/learn/nptel/104101135/00c1209263e6) (YouTube)
39. [Lecture 39 : NMR Analysis of Protein Dynamics III](https://invisiblenetwork.ai/learn/nptel/104101135/b6cfe1a8cc0d) (YouTube)
40. [Lecture 40 : NMR Analysis of Protein Dynamics IV](https://invisiblenetwork.ai/learn/nptel/104101135/199960181547) (YouTube)
41. [Lecture 41 : Protein-Ligand and Protein-Protein Interaction](https://invisiblenetwork.ai/learn/nptel/104101135/1a818a55909a) (YouTube)
42. [Lecture 42 : NMR Analysis of Ligand specific parameters in a Protein-Ligand Interaction I](https://invisiblenetwork.ai/learn/nptel/104101135/894ded1ecbf8) (YouTube)
43. [Lecture 43 : NMR Analysis of Ligand specific parameters in a Protein-Ligand Interaction II](https://invisiblenetwork.ai/learn/nptel/104101135/99b1047d0c23) (YouTube)
44. [Lecture 44 : NMR Analysis of Protein Specific Parameters in a Protein-Ligand Interaction I](https://invisiblenetwork.ai/learn/nptel/104101135/97c923faa976) (YouTube)
45. [Lecture 45 : NMR Analysis of Protein Specific Parameters in a Protein-Ligand Interaction II](https://invisiblenetwork.ai/learn/nptel/104101135/c34d2ea949a9) (YouTube)
46. [Lecture 46 : NMR in Drug Design](https://invisiblenetwork.ai/learn/nptel/104101135/fca4af08090e) (YouTube)
47. [Lecture 47 : NMR in Drug Discovery](https://invisiblenetwork.ai/learn/nptel/104101135/8d42d64b0c68) (YouTube)
48. [Lecture 48 : NMR in Drug metabolism I](https://invisiblenetwork.ai/learn/nptel/104101135/7f82aa64cd14) (YouTube)
49. [Lecture 49 : NMR in Drug metabolism II](https://invisiblenetwork.ai/learn/nptel/104101135/e211bcda91b1) (YouTube)
50. [Lecture 50 : NMR in Drug metabolism III](https://invisiblenetwork.ai/learn/nptel/104101135/a2d1126245d5) (YouTube)
51. [Lecture 51 : Probing Protein Dynamics by NMR Spectroscopy I](https://invisiblenetwork.ai/learn/nptel/104101135/cad7a9eba795) (YouTube)
52. [Lecture 52 : Probing Protein Dynamics by NMR Spectroscopy II](https://invisiblenetwork.ai/learn/nptel/104101135/1be9a57e9d9b) (YouTube)
53. [Lecture 53 : Probing Protein Dynamics by NMR Spectroscopy III](https://invisiblenetwork.ai/learn/nptel/104101135/a4585d1b1f6d) (YouTube)
54. [Lecture 54 : Probing Protein Dynamics by NMR Spectroscopy IV](https://invisiblenetwork.ai/learn/nptel/104101135/560d7e962085) (YouTube)
55. [Lecture 55 : Probing Protein Dynamics by NMR Spectroscopy V](https://invisiblenetwork.ai/learn/nptel/104101135/a1c8497be7d5) (YouTube)
56. [Lecture 56 : Basics of solid state NMR spectroscopy - I](https://invisiblenetwork.ai/learn/nptel/104101135/7dfc543f371a) (YouTube)
57. [Lecture 57 : Basics of solid state NMR spectroscopy - II](https://invisiblenetwork.ai/learn/nptel/104101135/e176e45e9331) (YouTube)
58. [Lecture 58 : Basics of solid state NMR spectroscopy - III](https://invisiblenetwork.ai/learn/nptel/104101135/2a7de6cc214c) (YouTube)
59. [Lecture 59 : Basics of solid state NMR spectroscopy - IV](https://invisiblenetwork.ai/learn/nptel/104101135/76110ea97b30) (YouTube)
60. [Lecture 60 : Basics of solid state NMR spectroscopy - V](https://invisiblenetwork.ai/learn/nptel/104101135/416b693b734e) (YouTube)
