# Medicinal Chemistry of Antimicrobial Agent

- Institution: IIT (BHU) Varanasi
- Department: Chemical Engineering
- Teacher: Prof. Deepak Kumar
- Level: Undergraduate
- Language: English
- Subjects: Chemistry, Engineering
- Source: [NPTEL](https://nptel.ac.in/courses/103106001)
- Licence: [CC BY-NC-SA](https://nptel.ac.in/faq) (Non-commercial use only.)
- Syllabus: [at the source](https://nptel.ac.in/courses/103106001)
- Who can watch: Teens profiles and older (sources give no ratings; placed by Invisible Network from the source's own words)

The course aims to provide students with a comprehensive understanding of antimicrobial drugs structure, chemistry and therapeutic values. The subject will emphasize on the chemistry, mechanism of action, metabolism, adverse effects, Structure Activity Relationships (SAR), therapeutic uses and synthesis of important drugs. This course sets the stage for exploring the fascinating world of antimicrobial drugs.

Intended audience: UG PG students interested in Chemistry and Medicinal ChemistryPREREQUISITES: Basics understanding of Chemistry, Pharmaceutical Chemistry, and Pharmacology

## Lectures

1. [Introduction & Historical Foundations: Historical background and General principles of antibiotics](https://invisiblenetwork.ai/learn/nptel/103106001/82a61e1ed545) (YouTube)
2. [Discovery and development of b-Lactam antibiotics](https://invisiblenetwork.ai/learn/nptel/103106001/c34f48696b9e) (YouTube)
3. [b-Lactam antibiotics (Penicillin)](https://invisiblenetwork.ai/learn/nptel/103106001/6c3904c24061) (YouTube)
4. [β-lactam antibiotics: Cephalosporin](https://invisiblenetwork.ai/learn/nptel/103106001/791207f1bb30) (YouTube)
5. [β-lactam antibiotics: Carbapenem and Monobactam](https://invisiblenetwork.ai/learn/nptel/103106001/4cb1a35f06e1) (YouTube)
6. [β Lactam Antibiotics MCQs](https://invisiblenetwork.ai/learn/nptel/103106001/11055909d0b4) (YouTube)
7. [Aminoglycosides](https://invisiblenetwork.ai/learn/nptel/103106001/5a7e7d0c207d) (YouTube)
8. [Streptomycin](https://invisiblenetwork.ai/learn/nptel/103106001/b828a3893407) (YouTube)
9. [Kanamycin](https://invisiblenetwork.ai/learn/nptel/103106001/c4caadb35f8f) (YouTube)
10. [Neomycin](https://invisiblenetwork.ai/learn/nptel/103106001/9158046a2926) (YouTube)
11. [General Overview of other aminoglycosides](https://invisiblenetwork.ai/learn/nptel/103106001/f72e76d87ea5) (YouTube)
12. [Aminoglycosides MCQs](https://invisiblenetwork.ai/learn/nptel/103106001/c9201df38051) (YouTube)
13. [Tetracyclins](https://invisiblenetwork.ai/learn/nptel/103106001/bb9c2a2ab979) (YouTube)
14. [Tetracyclin (as an individual drug)](https://invisiblenetwork.ai/learn/nptel/103106001/2841c9394255) (YouTube)
15. [Doxycycline](https://invisiblenetwork.ai/learn/nptel/103106001/ec13049faa7c) (YouTube)
16. [Tetracycline Synthesis by the Myers route](https://invisiblenetwork.ai/learn/nptel/103106001/d009cb9f4ff2) (YouTube)
17. [Tigecycline](https://invisiblenetwork.ai/learn/nptel/103106001/164e4dbdc6ed) (YouTube)
18. [Tetracyclines MCQs](https://invisiblenetwork.ai/learn/nptel/103106001/253b2e637489) (YouTube)
19. [Antitubercular Agents](https://invisiblenetwork.ai/learn/nptel/103106001/95c8a15b2176) (YouTube)
20. [Isoniazid and Ethambutol](https://invisiblenetwork.ai/learn/nptel/103106001/6a0b086279b9) (YouTube)
21. [Pyrazinamide](https://invisiblenetwork.ai/learn/nptel/103106001/782f755d3354) (YouTube)
22. [Rifampicin](https://invisiblenetwork.ai/learn/nptel/103106001/58bd935821e2) (YouTube)
23. [Dapsone](https://invisiblenetwork.ai/learn/nptel/103106001/2c1194e9e379) (YouTube)
24. [Anti mycobacterial Agents MCQs](https://invisiblenetwork.ai/learn/nptel/103106001/77c56c085b32) (YouTube)
25. [Quinolones](https://invisiblenetwork.ai/learn/nptel/103106001/add5725a0297) (YouTube)
26. [Fluoroquinolone and Synthesis of Ciprofloxacin](https://invisiblenetwork.ai/learn/nptel/103106001/369e559f62bd) (YouTube)
27. [Quinolones MCQs](https://invisiblenetwork.ai/learn/nptel/103106001/500cb6c19359) (YouTube)
28. [Fluoroquinolones- Ofloxacin and Levofloxacin](https://invisiblenetwork.ai/learn/nptel/103106001/6edb821f7be8) (YouTube)
29. [Fluoroquinolones- MCQs](https://invisiblenetwork.ai/learn/nptel/103106001/5c5c1e8f0de9) (YouTube)
30. [Overview on Viruses](https://invisiblenetwork.ai/learn/nptel/103106001/084202f9d0da) (YouTube)
31. [Amantadine and Rimantidien](https://invisiblenetwork.ai/learn/nptel/103106001/02b1277759a2) (YouTube)
32. [Amantadine and Rimantadine MCQs](https://invisiblenetwork.ai/learn/nptel/103106001/b0f8c37a0cea) (YouTube)
33. [Acyclovir: Synthesis and Mechanism of Action](https://invisiblenetwork.ai/learn/nptel/103106001/22f02bde3a5f) (YouTube)
34. [Lamivudine: Synthesis and Mechanism of Action](https://invisiblenetwork.ai/learn/nptel/103106001/648911653f94) (YouTube)
35. [Antiretrovirals (HIV therapy): Introduction and Classification](https://invisiblenetwork.ai/learn/nptel/103106001/f5fb1643b12a) (YouTube)
36. [Antiretrovirals (HIV therapy): Classifications](https://invisiblenetwork.ai/learn/nptel/103106001/266f79b3ea80) (YouTube)
37. [Antiretrovirals (HIV therapy) MCQs](https://invisiblenetwork.ai/learn/nptel/103106001/7e4ad4c50187) (YouTube)
38. [Retroviral Protease Inhibitors - PIs](https://invisiblenetwork.ai/learn/nptel/103106001/8233bc962fbe) (YouTube)
39. [Ritonavir Synthesis and SAR](https://invisiblenetwork.ai/learn/nptel/103106001/a10ee268077f) (YouTube)
40. [Introduction to fungal pathogens](https://invisiblenetwork.ai/learn/nptel/103106001/e29ac4abcf35) (YouTube)
41. [Polyene Antibiotics](https://invisiblenetwork.ai/learn/nptel/103106001/7284e407487f) (YouTube)
42. [MCQ on Antifungal Agents & Polyene Antibiotics](https://invisiblenetwork.ai/learn/nptel/103106001/689e6bcbc474) (YouTube)
43. [Inhibitors of Cell wall Biosynthesis- Echinocandins](https://invisiblenetwork.ai/learn/nptel/103106001/357a4d13b230) (YouTube)
44. [Drugs Acting through other mechanisms](https://invisiblenetwork.ai/learn/nptel/103106001/807389c2efb4) (YouTube)
45. [Synthesis of Fungal Cell Wall Components: Ergosterol Biosynthesis](https://invisiblenetwork.ai/learn/nptel/103106001/77236d48f9cc) (YouTube)
46. [Azole Antifungals Mechanism of Action & Metabolism](https://invisiblenetwork.ai/learn/nptel/103106001/3ff9ebaa7a74) (YouTube)
47. [MCQs on Ergosterol biosynthesis and Azole inhibitors](https://invisiblenetwork.ai/learn/nptel/103106001/e7e754629eb3) (YouTube)
48. [Ketoconazole and Clotromoxazole](https://invisiblenetwork.ai/learn/nptel/103106001/099ab9372875) (YouTube)
49. [Classification of Antifungal Drugs and MCQs](https://invisiblenetwork.ai/learn/nptel/103106001/64b6038659d9) (YouTube)
50. [Introduction to Antimalarial Drugs](https://invisiblenetwork.ai/learn/nptel/103106001/595d825ded0f) (YouTube)
51. [MCQs on Antimalarial Drugs](https://invisiblenetwork.ai/learn/nptel/103106001/118ba23c0f7b) (YouTube)
52. [Life Cycle of the Malarial Parasite and Antimalarial Drugs](https://invisiblenetwork.ai/learn/nptel/103106001/91b6e20a56dd) (YouTube)
53. [Quinoline based Antimalarial Drugs](https://invisiblenetwork.ai/learn/nptel/103106001/2ef88e44c268) (YouTube)
54. [Artemisinin and Other Antimalarial Drugs](https://invisiblenetwork.ai/learn/nptel/103106001/bf1890f25376) (YouTube)
55. [Metronidazole - Synthesis & Mechanism of Action](https://invisiblenetwork.ai/learn/nptel/103106001/323d3d0ed870) (YouTube)
56. [Nitroimidazole, Synthesis & Mechanism of Action](https://invisiblenetwork.ai/learn/nptel/103106001/e075750df536) (YouTube)
57. [Emetin Synthesis & Mechanism of Action](https://invisiblenetwork.ai/learn/nptel/103106001/bc9713bdc0c4) (YouTube)
58. [Dehydroemtin & Luminal Amoebicides](https://invisiblenetwork.ai/learn/nptel/103106001/850e7b93d169) (YouTube)
59. [Anti-Protozoal or Amoebic Drugs](https://invisiblenetwork.ai/learn/nptel/103106001/f695b327c263) (YouTube)
60. [Helminth Infection](https://invisiblenetwork.ai/learn/nptel/103106001/f8b0639a1764) (YouTube)
61. [Helminth Infection, Anthelmintics, Classification, Introduction](https://invisiblenetwork.ai/learn/nptel/103106001/6eed737d452c) (YouTube)
62. [Anthelmintics Synthesis](https://invisiblenetwork.ai/learn/nptel/103106001/aab9da8bf657) (YouTube)
63. [Anthelmintics - Ivermectin & Praziquantel](https://invisiblenetwork.ai/learn/nptel/103106001/c647f9881ba3) (YouTube)
64. [MCQs on Antihelmintic Drugs](https://invisiblenetwork.ai/learn/nptel/103106001/5680f97e6d2d) (YouTube)