# Structural Biology

- Institution: IIT Roorkee
- Department: Biotechnology
- Teacher: Prof. Saugata Hazra
- Level: Undergraduate
- Language: English
- Subjects: Biology
- Source: [NPTEL](https://nptel.ac.in/courses/102107086)
- Licence: [CC BY-NC-SA](https://nptel.ac.in/faq) (Non-commercial use only.)
- Syllabus: [at the source](https://nptel.ac.in/courses/102107086)
- Who can watch: Teens profiles and older (sources give no ratings; placed by Invisible Network from the source's own words)

## Lectures

1. [Introduction: Why to Study Structural Biology](https://invisiblenetwork.ai/learn/nptel/102107086/dd32d7506e93) (Video)
2. [Introduction to Biological Macromolecules](https://invisiblenetwork.ai/learn/nptel/102107086/f854ac59e36b) (Video)
3. [Introduction: Decoding Biological Macromolecules](https://invisiblenetwork.ai/learn/nptel/102107086/5048fb0bfec7) (Video)
4. [Introduction: Genome Sequencing](https://invisiblenetwork.ai/learn/nptel/102107086/a9d266be8eed) (Video)
5. [Introduction: Post Genomic Era](https://invisiblenetwork.ai/learn/nptel/102107086/f971431e082c) (Video)
6. [Amino acids and their properties](https://invisiblenetwork.ai/learn/nptel/102107086/66bc6f4d8115) (Video)
7. [Protein: Protein Chemistry, Chirality, Peptide bond and Levels of protein structures](https://invisiblenetwork.ai/learn/nptel/102107086/a2a6a638d182) (Video)
8. [Protein: Dihedral angles, Peptide bond and Ramachandran Plot](https://invisiblenetwork.ai/learn/nptel/102107086/8341e5fab7fd) (Video)
9. [Protein: Super Secondary Structures, Motif, Domains, Non-covalent interactions](https://invisiblenetwork.ai/learn/nptel/102107086/e6f8910ed90a) (Video)
10. [Protein: Folding of Protein, Thermodynamics and Kinetics of protein folding, Characterization of Proteins](https://invisiblenetwork.ai/learn/nptel/102107086/4e158a229988) (Video)
11. [Introduction to Structural Biology Techniques Part I](https://invisiblenetwork.ai/learn/nptel/102107086/0fe220d22a25) (Video)
12. [Introduction to Structural Biology Techniques Part II](https://invisiblenetwork.ai/learn/nptel/102107086/4a2f7c55a485) (Video)
13. [X-ray Crystallography: Crystallization Part I](https://invisiblenetwork.ai/learn/nptel/102107086/9b1c9d838487) (Video)
14. [X-ray Crystallography: Crystallization Part II](https://invisiblenetwork.ai/learn/nptel/102107086/bebd26f222f2) (Video)
15. [X-ray Crystallography: Crystal Mounting](https://invisiblenetwork.ai/learn/nptel/102107086/e4a1c33ed4dc) (Video)
16. [X-ray Crystallography: Production of X-ray and its properties](https://invisiblenetwork.ai/learn/nptel/102107086/5aeb581fb925) (Video)
17. [X-ray Crystallography: Journey to 3D land](https://invisiblenetwork.ai/learn/nptel/102107086/e6786e5b1343) (Video)
18. [X-ray Crystallography: Crystal Symmetry](https://invisiblenetwork.ai/learn/nptel/102107086/886cd560b34f) (Video)
19. [X-ray Crystallography: Instrumentation in X-ray Crystallography](https://invisiblenetwork.ai/learn/nptel/102107086/8d1125d86d83) (Video)
20. [X-ray Crystallography: Data collection and processing](https://invisiblenetwork.ai/learn/nptel/102107086/5125ca4f8d03) (Video)
21. [X-ray Crystallography: Data Analysis Part I](https://invisiblenetwork.ai/learn/nptel/102107086/51fd8a873ddf) (Video)
22. [X-ray Crystallography: Data Analysis Part II](https://invisiblenetwork.ai/learn/nptel/102107086/dd99204c1596) (Video)
23. [X-ray Crystallography: Phase Problem Part I](https://invisiblenetwork.ai/learn/nptel/102107086/8ba1701a6634) (Video)
24. [X-ray Crystallography: Phase Problem Part II](https://invisiblenetwork.ai/learn/nptel/102107086/bfd65ae2cc9a) (Video)
25. [X-ray Crystallography: Refinement and Structure deposition to PDB](https://invisiblenetwork.ai/learn/nptel/102107086/235cc88aafb8) (Video)
26. [Introduction to Spectroscopy and NMR](https://invisiblenetwork.ai/learn/nptel/102107086/02372367c74f) (Video)
27. [Basic Principles of NMR and Instrumentation](https://invisiblenetwork.ai/learn/nptel/102107086/b050cce33ba1) (Video)
28. [NMR Sample Preparation and Chemical Shift related concepts](https://invisiblenetwork.ai/learn/nptel/102107086/d8c99fd2b693) (Video)
29. [Factors effecting NMR Spectra (1D & 2D)](https://invisiblenetwork.ai/learn/nptel/102107086/37edabfb6b4e) (Video)
30. [2D & 3D NMR Spectroscopy focusing on protein structure](https://invisiblenetwork.ai/learn/nptel/102107086/ecf5d18e423f) (Video)
31. [Introduction to Spectroscopy.](https://invisiblenetwork.ai/learn/nptel/102107086/24c2a10415c2) (Video)
32. [UV-Vis and CD spectroscopy](https://invisiblenetwork.ai/learn/nptel/102107086/cf12418f4064) (Video)
33. [Fluorescence Spectroscopy and Green Fluorescence Protein (GFP)](https://invisiblenetwork.ai/learn/nptel/102107086/8472a5614071) (Video)
34. [Infrared & Raman Spectroscopy for protein](https://invisiblenetwork.ai/learn/nptel/102107086/6c200c222c4b) (Video)
35. [Raman Spectroscopy, Raman Microscopy and Raman Crystallography for studying protein](https://invisiblenetwork.ai/learn/nptel/102107086/38b759dc60b5) (Video)
36. [Introduction to Microscopy](https://invisiblenetwork.ai/learn/nptel/102107086/8c59a506e072) (Video)
37. [Functioning details of Cryo Electron Microscopy (Cryo EM)](https://invisiblenetwork.ai/learn/nptel/102107086/146d695ecec3) (Video)
38. [Cryo Electron Microscopy: Data Collection and Analysis](https://invisiblenetwork.ai/learn/nptel/102107086/aa8a612a67e4) (Video)
39. [A concise story of advancement Cryo-EM](https://invisiblenetwork.ai/learn/nptel/102107086/f130930797ed) (Video)
40. [Protein Data Bank](https://invisiblenetwork.ai/learn/nptel/102107086/3c012acee26c) (Video)
41. [History of Molecular Visualizations of Biological Macromolecules](https://invisiblenetwork.ai/learn/nptel/102107086/9af3947dd361) (Video)
42. [Description of structure related files (.pdb, .mmcif, .mtz, etc.)](https://invisiblenetwork.ai/learn/nptel/102107086/b6d254d2ddab) (Video)
43. [Demonstration of COOT](https://invisiblenetwork.ai/learn/nptel/102107086/5578f8119bd8) (Video)
44. [3D visualization using Pymol](https://invisiblenetwork.ai/learn/nptel/102107086/4429476b0a3e) (Video)
45. [Demonstration of Pymol](https://invisiblenetwork.ai/learn/nptel/102107086/9622a0fade97) (Video)
46. [Why we need MD Simulation](https://invisiblenetwork.ai/learn/nptel/102107086/b07dfb15302f) (Video)
47. [Molecular Dynamic Simulation Process: Part I](https://invisiblenetwork.ai/learn/nptel/102107086/427e50987828) (Video)
48. [Molecular Dynamic Simulation Process: Part II](https://invisiblenetwork.ai/learn/nptel/102107086/98c7491ce6cb) (Video)
49. [Molecular Dynamic Simulation Process: Part III](https://invisiblenetwork.ai/learn/nptel/102107086/2d413223b3ff) (Video)
50. [Application of Molecular Dynamic Simulation](https://invisiblenetwork.ai/learn/nptel/102107086/90206882e44b) (Video)
51. [What, How & Which of Protein Engineering](https://invisiblenetwork.ai/learn/nptel/102107086/f6a9b0ed4b14) (Video)
52. [How to make logical Protein Engineering: Process of Rational design](https://invisiblenetwork.ai/learn/nptel/102107086/79315a5c7411) (Video)
53. [Success story of Rational Protein designing: Focusing on De Novo Process](https://invisiblenetwork.ai/learn/nptel/102107086/a8c9cf3d34da) (Video)
54. [Designing Protein by mimicking nature: Process of Directed Evolution](https://invisiblenetwork.ai/learn/nptel/102107086/995db5147a4c) (Video)
55. [Achievement, Challenges, and Future direction in the field of Protein Engineering](https://invisiblenetwork.ai/learn/nptel/102107086/f9fe97e44681) (Video)
56. [Introduction to Structure Based Drug Discovery (SBDD)](https://invisiblenetwork.ai/learn/nptel/102107086/6a8c249dc9ce) (Video)
57. [Rational Drug Discovery](https://invisiblenetwork.ai/learn/nptel/102107086/4fd32473840c) (Video)
58. [Docking Based Virtual Screening: Progress, Challenges and Future perspective](https://invisiblenetwork.ai/learn/nptel/102107086/0767592faa36) (Video)
59. [What makes a small molecule an ideal drug: Developing in silico ADMETox Model](https://invisiblenetwork.ai/learn/nptel/102107086/c853f8bead23) (Video)
60. [Structure Based Drug Discovery: Case study and Conclusion](https://invisiblenetwork.ai/learn/nptel/102107086/75db2ac3016d) (Video)