# Epigenetics

- Institution: IIT Madras
- Department: Biotechnology
- Teacher: Prof. Arumugam Rajavelu
- Level: Undergraduate
- Language: English
- Subjects: Biology
- Source: [NPTEL](https://nptel.ac.in/courses/102106001)
- Licence: [CC BY-NC-SA](https://nptel.ac.in/faq) (Non-commercial use only.)
- Syllabus: [at the source](https://nptel.ac.in/courses/102106001)
- Who can watch: Teens profiles and older (sources give no ratings; placed by Invisible Network from the source's own words)

Epigenetics is new branch of biology discipline which deals about the study of changes of gene activity without altering the underlying DNA sequence and can be strongly influenced by environmental factors. The eukaryotes are subjected to cell and tissues specific differential gene expression, despite every cells contains the same genetic information. The critical regulators which control these processes are epigenetic players. The fine-tuning of gene expression in every cells are essential for successful development of cells/organisms. Mis-regulation of epigenetics players leads to many chronic diseases. Therefore, it is essential to understand the fundamental process of genes regulation. This course will provide the platform to learn the basics of Molecular Epigenetics, a new layer of gene regulation in eukaryotes and epigenome projects.

Intended audience: Final year B.Tech / M.Sc / M.Tech / MS / PhD Life Sciences

Prerequisites: Molecular Biology

## Lectures

1. [Introduction to Epigenetics](https://invisiblenetwork.ai/learn/nptel/102106001/56e74e8d2873) (YouTube)
2. [DNA structure and organization](https://invisiblenetwork.ai/learn/nptel/102106001/0043f5f908f4) (YouTube)
3. [Epigenetics Phenomena](https://invisiblenetwork.ai/learn/nptel/102106001/4900ee354306) (YouTube)
4. [Introduction to Epigenetic players](https://invisiblenetwork.ai/learn/nptel/102106001/76e5334c84ab) (YouTube)
5. [DNA methylation](https://invisiblenetwork.ai/learn/nptel/102106001/ccaf059a5143) (YouTube)
6. [De novo DNA methylation](https://invisiblenetwork.ai/learn/nptel/102106001/a662a91f0994) (YouTube)
7. [Functions and regulation of DNMTs](https://invisiblenetwork.ai/learn/nptel/102106001/25fb7ed71a86) (YouTube)
8. [Erasure of DNA methylation](https://invisiblenetwork.ai/learn/nptel/102106001/20a9d8ddbd1f) (YouTube)
9. [Epitranscriptome](https://invisiblenetwork.ai/learn/nptel/102106001/9740eda70dbf) (YouTube)
10. [Regulators of Epitrasncriptome](https://invisiblenetwork.ai/learn/nptel/102106001/98f6247bea7b) (YouTube)
11. [Epigenetic methods Part I](https://invisiblenetwork.ai/learn/nptel/102106001/230e6f9fc3cd) (YouTube)
12. [Epigenetic methods Part II and Epigenome Editing](https://invisiblenetwork.ai/learn/nptel/102106001/0f5944f6e6db) (YouTube)
13. [Introduction to chromatin epigenetics](https://invisiblenetwork.ai/learn/nptel/102106001/b6695e642402) (YouTube)
14. [Nucleosome assembly & histone inheritance](https://invisiblenetwork.ai/learn/nptel/102106001/853389f9f066) (YouTube)
15. [Chromatin remodelling](https://invisiblenetwork.ai/learn/nptel/102106001/a40dabc0c5ab) (YouTube)
16. [comprehensive check Week 3&4](https://invisiblenetwork.ai/learn/nptel/102106001/9153d44d8906) (YouTube)
17. [Histone code: Acetylation](https://invisiblenetwork.ai/learn/nptel/102106001/4c3e81253e62) (YouTube)
18. [Chromatin Epigenetics Methods](https://invisiblenetwork.ai/learn/nptel/102106001/2d09168efe2b) (YouTube)
19. [Histone code: HAT & HDAC](https://invisiblenetwork.ai/learn/nptel/102106001/30fde78d6468) (YouTube)
20. [Basics of Histone lysine methylation](https://invisiblenetwork.ai/learn/nptel/102106001/cd99516a2811) (YouTube)
21. [Histone code: H3K4 methylation](https://invisiblenetwork.ai/learn/nptel/102106001/8918c9b8d7b3) (YouTube)
22. [Histone code: H3K9 methylation](https://invisiblenetwork.ai/learn/nptel/102106001/afbaf6cb02d0) (YouTube)
23. [Histone code: H3K27 methylation](https://invisiblenetwork.ai/learn/nptel/102106001/c214644d9970) (YouTube)
24. [Histone code: H3K36 and H4K20](https://invisiblenetwork.ai/learn/nptel/102106001/dc3f3ca2eeef) (YouTube)
25. [Comprehensive check Week 5 & 6](https://invisiblenetwork.ai/learn/nptel/102106001/a4527bfc102a) (YouTube)
26. [Histone core modifications and its fucntions](https://invisiblenetwork.ai/learn/nptel/102106001/233a07f29f96) (YouTube)
27. [Epigenetic Readers - Part 1](https://invisiblenetwork.ai/learn/nptel/102106001/3cd11d99fe72) (YouTube)
28. [Epigenetic Readers - Part 2](https://invisiblenetwork.ai/learn/nptel/102106001/634befe165e3) (YouTube)
29. [Epigenetic erasers](https://invisiblenetwork.ai/learn/nptel/102106001/74fed876269b) (YouTube)
30. [lncRNA epigenetics](https://invisiblenetwork.ai/learn/nptel/102106001/0d6e9e51210f) (YouTube)
31. [Small RNAs and Epigenetics](https://invisiblenetwork.ai/learn/nptel/102106001/b45ee955bbf3) (YouTube)
32. [miRNA and piRNA Epigenetics](https://invisiblenetwork.ai/learn/nptel/102106001/2e787fb0b599) (YouTube)
33. [Stem Cell Epigenetics](https://invisiblenetwork.ai/learn/nptel/102106001/4ad8cc137e2d) (YouTube)
34. [Stem cell reprogramming](https://invisiblenetwork.ai/learn/nptel/102106001/6e9db44f3c36) (YouTube)
35. [Genomic imprinting](https://invisiblenetwork.ai/learn/nptel/102106001/e75a5fe94fab) (YouTube)
36. [Plant Epigenetics](https://invisiblenetwork.ai/learn/nptel/102106001/9d93a0154d51) (YouTube)
37. [Model organisms for Epigenetic research - Part 1](https://invisiblenetwork.ai/learn/nptel/102106001/72c3d7319587) (YouTube)
38. [Model organisms for Epigenetic research - Part 2](https://invisiblenetwork.ai/learn/nptel/102106001/110a1be027cb) (YouTube)
39. [Model organisms for Epigenetic research - Part 3](https://invisiblenetwork.ai/learn/nptel/102106001/4300558c3c7f) (YouTube)
40. [Epigenetics of Chronic Diseases - Part 1](https://invisiblenetwork.ai/learn/nptel/102106001/14c077a4d949) (YouTube)
41. [Epigenetics of Chronic Diseases - Part 2](https://invisiblenetwork.ai/learn/nptel/102106001/d73a92365e49) (YouTube)
42. [Epigenome Projects](https://invisiblenetwork.ai/learn/nptel/102106001/28c9048704ef) (YouTube)